STRINGSTRING
sup-37 sup-37 pyr-1 pyr-1 mig-5 mig-5 nas-6 nas-6 ensh-1 ensh-1 umps-1 umps-1 mab-9.2 mab-9.2 aph-1 aph-1 CBG25505 CBG25505 CBG25832 CBG25832 CBG23879 CBG23879 CBG23773 CBG23773 sqv-8 sqv-8 lin-53 lin-53 cdc-42 cdc-42 farl-11 farl-11 nas-7 nas-7 rsa-2 rsa-2 pen-2 pen-2 swsn-7 swsn-7 CBG13640 CBG13640 eps-8 eps-8 peb-1 peb-1 exc-6 exc-6 CBG15416 CBG15416 toca-1 toca-1 CBG16381 CBG16381 CBG16347 CBG16347 ubc-18 ubc-18 lin-37 lin-37 CBG16516 CBG16516 sma-3 sma-3 ten-1 ten-1 apy-1 apy-1 CBG16744 CBG16744 egl-15 egl-15 act-5 act-5 toca-2 toca-2 rib-2 rib-2 sqv-1 sqv-1 efl-1 efl-1 wve-1 wve-1 mrck-1 mrck-1 gck-1 gck-1 hlh-10 hlh-10 CBG19636 CBG19636 CBG19815 CBG19815 CBG20127 CBG20127 rig-6 rig-6 tig-3 tig-3 mig-14 mig-14 CBG20736 CBG20736 tbx-2 tbx-2 aph-2 aph-2 src-1 src-1 mks-1 mks-1 sup-36 sup-36 erm-1 erm-1 lin-36 lin-36 srj-4 srj-4 CBG23395 CBG23395 sma-1 sma-1 cec-7 cec-7 tnt-4 tnt-4 lin-59 lin-59 CBG11789 CBG11789 hil-1 hil-1 str-28.1 str-28.1 mom-2 mom-2 unc-52 unc-52 CBG10974 CBG10974 CBG10973 CBG10973 str-27 str-27 cash-1 cash-1 ceh-22 ceh-22 lin-48 lin-48 hmg-4 hmg-4 wrm-1 wrm-1 CBG09063 CBG09063 src-2 src-2 let-413 let-413 Cbr-abu-6 Cbr-abu-6 Cbr-abu-7 Cbr-abu-7 CBG08691 CBG08691 Cbr-abu-8 Cbr-abu-8 pha-2 pha-2 CBG07973 CBG07973 CBG07669 CBG07669 CBG07744 CBG07744 mab-9.1 mab-9.1 sma-2 sma-2 glp-1 glp-1 hlh-6 hlh-6 CBG06569 CBG06569 rib-1 rib-1 let-653 let-653 gck-3 gck-3 pha-4 pha-4 CBG05575 CBG05575 CBG05231 CBG05231 ceh-28 ceh-28 lpr-1 lpr-1 hda-1 hda-1 CBG04337 CBG04337 CBG12570 CBG12570 nas-5 nas-5 mom-5 mom-5 sys-1 sys-1 pop-1 pop-1 hmg-3 hmg-3 lin-35 lin-35 lim-7 lim-7 pxd-1 pxd-1 CBG03621 CBG03621 ndnf-1 ndnf-1 gex-3 gex-3 dsh-2 dsh-2 CBG02351 CBG02351 CBG02722 CBG02722 ccm-3 ccm-3 CBG03052 CBG03052 vang-1 vang-1 wsp-1 wsp-1 CBG01565 CBG01565 ubc-9 ubc-9 abu-14 abu-14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sup-37Protein CBG00762. (987 aa)
pyr-1Protein CBR-PYR-1. (2090 aa)
mig-5Protein CBR-MIG-5. (657 aa)
nas-6Metalloendopeptidase. (341 aa)
ensh-1Protein CBG00249. (497 aa)
umps-1Protein CBR-UMPS-1. (498 aa)
mab-9.2Protein CBR-MAB-9.2. (342 aa)
aph-1Protein CBR-APH-1. (330 aa)
CBG25505Protein CBG25505. (207 aa)
CBG25832Protein CBG25832. (61 aa)
CBG23879Protein CBG23879. (272 aa)
CBG23773Protein CBG23773. (514 aa)
sqv-8Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (356 aa)
lin-53Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. (416 aa)
cdc-42Protein CBR-CDC-42. (191 aa)
farl-11Protein CBG13065. (976 aa)
nas-7Metalloendopeptidase. (389 aa)
rsa-2Protein CBR-RSA-2. (1045 aa)
pen-2Protein CBR-PEN-2. (101 aa)
swsn-7Protein CBR-SWSN-7. (1221 aa)
CBG13640Protein CBG13640. (1232 aa)
eps-8Protein CBR-EPS-8. (918 aa)
peb-1Protein CBR-PEB-1. (432 aa)
exc-6Protein CBR-INFT-1. (901 aa)
CBG15416Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (470 aa)
toca-1Protein CBR-TOCA-1. (588 aa)
CBG16381Protein CBG16381. (516 aa)
CBG16347Protein CBG16347. (191 aa)
ubc-18Protein CBR-UBC-18. (153 aa)
lin-37Protein CBR-LIN-37. (274 aa)
CBG16516Protein CBG16516. (225 aa)
sma-3Dwarfin sma. (365 aa)
ten-1Protein CBR-TEN-1. (2909 aa)
apy-1Protein CBG16731. (354 aa)
CBG16744Protein CBG16744. (663 aa)
egl-15Receptor protein-tyrosine kinase. (1192 aa)
act-5Protein CBR-ACT-5. (375 aa)
toca-2Protein CBR-TOCA-2. (677 aa)
rib-2Protein CBR-RIB-2; Belongs to the glycosyltransferase 47 family. (877 aa)
sqv-1Protein CBR-SQV-1. (456 aa)
efl-1Protein CBR-EFL-1. (303 aa)
wve-1Protein CBR-WVE-1. (475 aa)
mrck-1Protein CBR-MRCK-1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1586 aa)
gck-1Protein CBR-GCK-1. (898 aa)
hlh-10Protein CBR-HLH-10. (271 aa)
CBG19636Protein CBG19636. (554 aa)
CBG19815Protein CBG19815. (290 aa)
CBG20127Protein CBG20127. (413 aa)
rig-6Protein CBR-RIG-6. (1297 aa)
tig-3Protein CBR-TIG-3. (225 aa)
mig-14Protein CBR-MIG-14. (548 aa)
CBG20736Protein CBG20736; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
tbx-2Protein CBR-TBX-2. (426 aa)
aph-2Protein CBR-APH-2. (721 aa)
src-1Tyrosine-protein kinase. (544 aa)
mks-1Protein CBR-MKS-1. (384 aa)
sup-36Protein CBG23027. (169 aa)
erm-1Protein CBR-ERM-1. (563 aa)
lin-36Protein CBR-LIN-36. (1111 aa)
srj-4Protein CBR-SRJ-4. (335 aa)
CBG23395Protein CBG23395. (359 aa)
sma-1Protein CBR-SMA-1. (4156 aa)
cec-7Protein CBG23260. (528 aa)
tnt-4Protein CBR-TNT-4. (308 aa)
lin-59Protein CBR-LIN-59. (1320 aa)
CBG11789Protein CBG11789. (244 aa)
hil-1Protein CBR-HIL-1. (233 aa)
str-28.1Protein CBR-STR-28. (316 aa)
mom-2Protein CBR-MOM-2. (358 aa)
unc-52Protein CBR-UNC-52. (2481 aa)
CBG10974Protein CBG10974. (318 aa)
CBG10973Protein CBG10973. (372 aa)
str-27Protein CBG09327. (235 aa)
cash-1Protein CBR-CASH-1. (681 aa)
ceh-22Protein CBR-CEH-22. (356 aa)
lin-48Protein CBR-LIN-48. (290 aa)
hmg-4FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (695 aa)
wrm-1Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa)
CBG09063Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
src-2Tyrosine-protein kinase. (512 aa)
let-413Protein CBR-LET-413. (702 aa)
Cbr-abu-6Protein CBR-ABU-6. (383 aa)
Cbr-abu-7Protein CBR-ABU-7. (432 aa)
CBG08691Protein CBG08691. (326 aa)
Cbr-abu-8Protein CBR-ABU-8. (443 aa)
pha-2Protein CBR-PHA-2. (211 aa)
CBG07973NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (235 aa)
CBG07669Protein CBG07669. (2178 aa)
CBG07744Protein CBG07744. (308 aa)
mab-9.1Protein CBR-MAB-9.1. (331 aa)
sma-2Dwarfin sma. (399 aa)
glp-1Protein CBR-GLP-1. (1326 aa)
hlh-6Protein CBR-HLH-6. (144 aa)
CBG06569Protein CBG06569. (347 aa)
rib-1Protein CBR-RIB-1; Belongs to the glycosyltransferase 47 family. (343 aa)
let-653Protein CBR-LET-653. (736 aa)
gck-3Protein CBR-GCK-3. (596 aa)
pha-4Protein CBR-PHA-4. (477 aa)
CBG05575Protein CBG05575. (166 aa)
CBG05231Protein CBG05231; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
ceh-28Protein CBR-CEH-28. (100 aa)
lpr-1Protein CBR-LPR-1. (232 aa)
hda-1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
CBG04337Protein CBG04337. (331 aa)
CBG12570Protein CBG12570. (1945 aa)
nas-5Metalloendopeptidase. (372 aa)
mom-5Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
sys-1Protein CBR-SYS-1. (839 aa)
pop-1Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage- derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. Belongs t [...] (439 aa)
hmg-3FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (689 aa)
lin-35Protein CBR-LIN-35. (956 aa)
lim-7Protein CBR-LIM-7. (458 aa)
pxd-1Protein CBR-PXD-1. (515 aa)
CBG03621Protein CBG03621. (549 aa)
ndnf-1Protein CBR-NDNF-1. (536 aa)
gex-3Protein CBR-GEX-3. (1140 aa)
dsh-2Protein CBR-DSH-2. (784 aa)
CBG02351Protein CBG02351. (91 aa)
CBG02722Protein CBG02722. (311 aa)
ccm-3Protein CBG03050. (215 aa)
CBG03052Protein CBG03052. (74 aa)
vang-1Vang-like protein. (532 aa)
wsp-1Protein CBR-WSP-1. (785 aa)
CBG01565Protein CBG01565. (188 aa)
ubc-9Protein CBR-UBC-9; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
abu-14Protein CBR-ABU-14. (383 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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