STRINGSTRING
Cbr-unc-79.1 Cbr-unc-79.1 bro-1 bro-1 unc-63 unc-63 CBG24089 CBG24089 adr-2 adr-2 lam-3 lam-3 Cbr-hlh-12 Cbr-hlh-12 stn-1 stn-1 ilc-17.1 ilc-17.1 CBG00206 CBG00206 dab-1 dab-1 fat-1 fat-1 osm-5 osm-5 ilcr-2 ilcr-2 mca-3 mca-3 cwn-2 cwn-2 egl-20 egl-20 pat-3 pat-3 vps-51 vps-51 rnt-1 rnt-1 lin-17 lin-17 mom-5 mom-5 ebax-1 ebax-1 epi-1 epi-1 unc-112 unc-112 unc-39 unc-39 mig-1 mig-1 unc-9 unc-9 unc-77 unc-77 unc-80 unc-80 calf-1 calf-1 unc-22 unc-22 egl-19 egl-19 egl-8 egl-8 eat-4 eat-4 CBG06794 CBG06794 ina-1 ina-1 pat-2 pat-2 cwn-1 cwn-1 CBG07774 CBG07774 atrn-1 atrn-1 hlb-1 hlb-1 dyc-1 dyc-1 gsk-3 gsk-3 rund-1 rund-1 egl-21 egl-21 ced-5 ced-5 CBG09064 CBG09064 hpo-28 hpo-28 ced-6 ced-6 snf-10 snf-10 egl-3 egl-3 wdr-20 wdr-20 zmp-2 zmp-2 usp-46 usp-46 vps-53 vps-53 CBG10002 CBG10002 ced-7 ced-7 dat-1 dat-1 lam-2 lam-2 unc-6 unc-6 unc-52 unc-52 mom-2 mom-2 snf-6 snf-6 lrp-1 lrp-1 ccb-1 ccb-1 smp-2 smp-2 lin-44 lin-44 unc-89 unc-89 unc-29 unc-29 che-1 che-1 CBG12999 CBG12999 daf-18 daf-18 ced-2 ced-2 che-2 che-2 rho-1 rho-1 CBG13699 CBG13699 lin-18 lin-18 mig-13 mig-13 unc-97 unc-97 unc-40 unc-40 ced-10 ced-10 lec-6 lec-6 grk-2 grk-2 CBG15339 CBG15339 pgrn-1 pgrn-1 dys-1 dys-1 Cbr-dys-1 Cbr-dys-1 Cbr-pat-4 Cbr-pat-4 vav-1 vav-1 cil-1 cil-1 rbf-1 rbf-1 vps-52 vps-52 dgn-1 dgn-1 inpp-1 inpp-1 unc-34 unc-34 vps-50 vps-50 acy-1 acy-1 glr-1 glr-1 hlh-12.1 hlh-12.1 CBG18500 CBG18500 plc-3 plc-3 ilcr-1 ilcr-1 CBG18780 CBG18780 CBG19078 CBG19078 dop-2 dop-2 unc-41 unc-41 eipr-1 eipr-1 aex-5 aex-5 smp-1 smp-1 unc-5 unc-5 sand-1 sand-1 fbl-1 fbl-1 CBG20127 CBG20127 Cbr-unc-79 Cbr-unc-79 unc-79 unc-79 unc-38 unc-38 CBG20569 CBG20569 rig-6 rig-6 CBG20664 CBG20664 cacn-1 cacn-1 CBG21241 CBG21241 CBG21771 CBG21771 hlh-2 hlh-2 spd-1 spd-1 egl-30 egl-30 src-1 src-1 dyb-1 dyb-1 cfz-2 cfz-2 CBG22464 CBG22464 pat-6 pat-6 egl-10 egl-10 CBG23464 CBG23464 pkc-1 pkc-1 deg-3 deg-3 CBG11409 CBG11409 CBG26388 CBG26388 CBG26587 CBG26587 CBG26190 CBG26190 CBG26191 CBG26191 CBG18730 CBG18730 lin-10 lin-10 CBG25156 CBG25156 unc-53 unc-53 mab-20 mab-20 CBG09753 CBG09753 odr-8 odr-8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Cbr-unc-79.1Protein CBR-UNC-79.1. (237 aa)
bro-1Protein CBR-BRO-1. (155 aa)
unc-63Protein CBR-UNC-63. (502 aa)
CBG24089Protein CBG24089; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (247 aa)
adr-2Protein CBR-ADR-2. (497 aa)
lam-3Protein CBR-LAM-3. (3141 aa)
Cbr-hlh-12Protein CBR-HLH-12. (193 aa)
stn-1Protein CBR-STN-1. (422 aa)
ilc-17.1Protein CBG00075. (222 aa)
CBG00206Protein CBG00206; Belongs to the protein kinase superfamily. (350 aa)
dab-1Protein CBR-DAB-1. (483 aa)
fat-1Protein CBR-FAT-1. (399 aa)
osm-5Protein CBR-OSM-5. (863 aa)
ilcr-2Protein CBG02408. (730 aa)
mca-3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1159 aa)
cwn-2Protein CBR-CWN-2. (360 aa)
egl-20Protein CBR-EGL-20. (398 aa)
pat-3Integrin beta; Belongs to the integrin beta chain family. (818 aa)
vps-51Protein CBR-VPS-51. (695 aa)
rnt-1Protein CBR-RNT-1. (312 aa)
lin-17Protein CBR-LIN-17; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
mom-5Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
ebax-1Protein CBR-PQN-55. (1703 aa)
epi-1Protein CBR-EPI-1. (3820 aa)
unc-112Protein CBR-UNC-112. (720 aa)
unc-39Protein CBR-UNC-39. (315 aa)
mig-1Protein CBR-MIG-1; Belongs to the G-protein coupled receptor Fz/Smo family. (518 aa)
unc-9Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (449 aa)
unc-77Protein CBR-NCA-1. (1883 aa)
unc-80Protein CBR-UNC-80. (3520 aa)
calf-1Protein CBR-CALF-1. (150 aa)
unc-22Protein CBR-UNC-22. (7455 aa)
egl-19Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1780 aa)
egl-8Phosphoinositide phospholipase C. (1528 aa)
eat-4Protein CBR-EAT-4. (582 aa)
CBG06794Protein CBG06794. (204 aa)
ina-1Protein CBR-INA-1; Belongs to the integrin alpha chain family. (1147 aa)
pat-2Integrin alpha pat-2; Required for muscle development probably through the regulation of the actin-myosin cytoskeleton. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52. Required for distal tip cell migration and dorsal pathfinding. Required for egg-laying. May play a role in cell motility and cell-cell interactions. (1224 aa)
cwn-1Protein CBR-CWN-1. (372 aa)
CBG07774Protein CBG07774. (612 aa)
atrn-1Protein CBR-TAG-53. (1337 aa)
hlb-1Protein CBR-HLB-1. (912 aa)
dyc-1Protein CBR-DYC-1. (985 aa)
gsk-3Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa)
rund-1Protein CBG08133. (564 aa)
egl-21Protein CBR-EGL-21. (473 aa)
ced-5Protein CBR-CED-5; Belongs to the DOCK family. (1820 aa)
CBG09064Protein CBG09064. (404 aa)
hpo-28Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (569 aa)
ced-6Protein CBR-CED-6. (490 aa)
snf-10Protein CBR-SNF-10. (673 aa)
egl-3Protein CBR-EGL-3; Belongs to the peptidase S8 family. (662 aa)
wdr-20Protein CBR-HPO-22. (763 aa)
zmp-2Protein CBG09830. (489 aa)
usp-46Ubiquitin carboxyl-terminal hydrolase. (415 aa)
vps-53Protein CBG09978. (796 aa)
CBG10002Protein CBG10002. (768 aa)
ced-7Protein CBR-CED-7. (1784 aa)
dat-1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (622 aa)
lam-2Protein CBR-LAM-2. (1646 aa)
unc-6Protein CBR-UNC-6. (621 aa)
unc-52Protein CBR-UNC-52. (2481 aa)
mom-2Protein CBR-MOM-2. (358 aa)
snf-6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (709 aa)
lrp-1Protein CBR-LRP-1. (4829 aa)
ccb-1Protein CBR-CCB-1. (523 aa)
smp-2Protein CBR-SMP-2; Belongs to the semaphorin family. (689 aa)
lin-44Abnormal cell lineage protein 44; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Affects male tail development, vulval precursor cell specification and egg laying. Involved in morphogenesis by influencing polarity of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites. Controls spindle orientation in B-gamma cell division during male copulatory spicule development. Involved in specification of the P7.p lineage during vulval development. Has a role in providing polarity and default lin-17 [...] (341 aa)
unc-89Protein CBR-UNC-89. (6561 aa)
unc-29Protein CBR-UNC-29. (491 aa)
che-1Protein CBR-CHE-1. (281 aa)
CBG12999Protein CBG12999. (256 aa)
daf-18Protein CBR-DAF-18. (992 aa)
ced-2Cell death abnormality protein 2; Required for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis. Also has a role in the migration of the 2 gonadal distal tip cells (DTCs) (By similarity). Belongs to the CRK family. (277 aa)
che-2Protein CBR-CHE-2. (761 aa)
rho-1Protein CBR-RHO-1. (192 aa)
CBG13699Protein CBG13699. (277 aa)
lin-18Protein CBR-LIN-18. (599 aa)
mig-13Protein CBR-MIG-13. (360 aa)
unc-97LIM domain-containing protein. (353 aa)
unc-40Protein CBR-UNC-40. (1407 aa)
ced-10Protein CBG15031. (191 aa)
lec-6Galectin. (146 aa)
grk-2Protein CBR-GRK-2. (377 aa)
CBG15339Protein CBG15339. (331 aa)
pgrn-1Protein CBR-PGRN-1. (291 aa)
dys-1Protein CBG15371. (1276 aa)
Cbr-dys-1Protein CBR-DYS-1. (2353 aa)
Cbr-pat-4Protein CBR-PAT-4. (278 aa)
vav-1Protein CBR-VAV-1. (971 aa)
cil-1Protein CBR-CIL-1. (398 aa)
rbf-1Protein CBR-RBF-1. (1021 aa)
vps-52Protein CBR-VPS-52. (702 aa)
dgn-1Protein CBR-DGN-1. (594 aa)
inpp-1Protein CBG17633. (417 aa)
unc-34Protein CBR-UNC-34. (459 aa)
vps-50Protein CBG18297. (930 aa)
acy-1Protein CBR-ACY-1. (1287 aa)
glr-1Protein CBR-GLR-1. (978 aa)
hlh-12.1Protein CBG18498. (159 aa)
CBG18500Protein CBG18500. (61 aa)
plc-31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1308 aa)
ilcr-1Protein CBG18736. (836 aa)
CBG18780Protein CBG18780. (263 aa)
CBG19078Protein CBG19078. (606 aa)
dop-2Protein CBR-DOP-2; Belongs to the G-protein coupled receptor 1 family. (852 aa)
unc-41Protein CBR-UNC-41. (1661 aa)
eipr-1Protein CBG19781. (353 aa)
aex-5Protein CBR-AEX-5. (541 aa)
smp-1Protein CBR-SMP-1; Belongs to the semaphorin family. (714 aa)
unc-5Protein CBR-UNC-5. (922 aa)
sand-1Protein CBR-SAND-1. (460 aa)
fbl-1Protein CBR-FBL-1. (925 aa)
CBG20127Protein CBG20127. (413 aa)
Cbr-unc-79Protein CBR-UNC-79. (858 aa)
unc-79Protein CBR-UNC-79.2. (1163 aa)
unc-38Protein CBR-UNC-38. (510 aa)
CBG20569Protein CBG20569. (299 aa)
rig-6Protein CBR-RIG-6. (1297 aa)
CBG20664Protein CBG20664. (209 aa)
cacn-1Protein CBR-CACN-1. (690 aa)
CBG21241Protein CBG21241. (192 aa)
CBG21771Protein CBG21771. (246 aa)
hlh-2Protein CBR-HLH-2. (426 aa)
spd-1Protein CBR-SPD-1. (523 aa)
egl-30Protein CBR-EGL-30. (388 aa)
src-1Tyrosine-protein kinase. (544 aa)
dyb-1Dystrobrevin. (622 aa)
cfz-2Protein CBR-CFZ-2; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
CBG22464Protein CBG22464. (603 aa)
pat-6Protein CBR-PAT-6. (379 aa)
egl-10Protein CBR-EGL-10. (549 aa)
CBG23464Protein CBG23464. (800 aa)
pkc-1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
deg-3Protein CBR-DEG-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (522 aa)
CBG11409Protein CBG11409. (685 aa)
CBG26388Protein CBG26388. (223 aa)
CBG26587Protein CBG26587. (599 aa)
CBG26190Protein CBG26190. (209 aa)
CBG26191Protein CBG26191. (237 aa)
CBG18730Protein CBG18730. (1378 aa)
lin-10Protein CBR-LIN-10, isoform a. (1120 aa)
CBG25156Protein CBG25156. (183 aa)
unc-53Protein CBR-UNC-53, isoform a. (1778 aa)
mab-20Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (656 aa)
CBG09753Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility; Belongs to the CFAP20 family. (203 aa)
odr-8Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins. Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels. (588 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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