STRINGSTRING
CBG23907 CBG23907 CBG23920 CBG23920 rpn-11 rpn-11 rpn-2 rpn-2 srh-186 srh-186 CBG24312 CBG24312 Cbr-gadr-3 Cbr-gadr-3 ubc-1 ubc-1 CBG24536 CBG24536 CBG24537 CBG24537 CBG24538 CBG24538 fzr-1 fzr-1 CBG00481 CBG00481 Cbr-skr-10 Cbr-skr-10 CBG00496 CBG00496 CBG00499 CBG00499 cdc-48.2 cdc-48.2 emb-27 emb-27 CBG00586 CBG00586 usp-14 usp-14 ufd-3 ufd-3 CBG00897 CBG00897 CBG01819 CBG01819 CBG01952 CBG01952 CBG02109 CBG02109 CBG02202 CBG02202 cup-2 cup-2 cdc-48.1 cdc-48.1 mat-2 mat-2 rpn-12 rpn-12 CBG02791 CBG02791 fzy-1 fzy-1 CBG02414 CBG02414 CBG02386 CBG02386 pbs-3 pbs-3 sgt-1 sgt-1 ufd-1 ufd-1 eel-1 eel-1 CBG03437 CBG03437 CBG03913 CBG03913 CBG04230 CBG04230 skr-1 skr-1 CBG04254 CBG04254 CBG04283 CBG04283 CBG04287 CBG04287 rpn-5 rpn-5 CBG04755 CBG04755 CBG04772 CBG04772 CBG04780 CBG04780 wwp-1 wwp-1 skpt-1 skpt-1 CBG05191 CBG05191 skr-20 skr-20 skr-19 skr-19 skr-21 skr-21 ddb-1 ddb-1 dnj-1 dnj-1 enpl-1 enpl-1 skr-16 skr-16 CBG05790 CBG05790 hecd-1 hecd-1 rpn-1 rpn-1 CBG06331 CBG06331 Cbr-tag-304 Cbr-tag-304 CBG06669 CBG06669 nhl-1 nhl-1 CBG06886 CBG06886 CBG07183 CBG07183 ubxn-3 ubxn-3 rpt-4 rpt-4 CBG07636 CBG07636 gfi-3 gfi-3 ubc-14 ubc-14 grd-15 grd-15 siah-1 siah-1 CBG08535 CBG08535 CBG08732 CBG08732 CBG08741 CBG08741 CBG08898 CBG08898 rpt-3 rpt-3 CBG09040 CBG09040 madf-11 madf-11 CBG09125 CBG09125 CBG09126 CBG09126 CBG09205 CBG09205 apc-10 apc-10 cul-5 cul-5 rpt-2 rpt-2 Cbr-jamp-1 Cbr-jamp-1 CBG09804 CBG09804 hecw-1 hecw-1 CBG09885 CBG09885 bath-43 bath-43 cnx-1 cnx-1 ubc-7 ubc-7 ubql-1 ubql-1 mat-1 mat-1 CBG10989 CBG10989 CBG10845 CBG10845 CBG11069 CBG11069 aip-1 aip-1 cdt-2 cdt-2 CBG11722 CBG11722 rpt-6 rpt-6 ubr-1 ubr-1 rpn-8 rpn-8 CBG11949 CBG11949 wdr-23 wdr-23 marc-6 marc-6 CBG12265 CBG12265 mel-26 mel-26 rpn-10 rpn-10 rpt-5 rpt-5 chn-1 chn-1 mat-3 mat-3 skr-17 skr-17 CBG12958 CBG12958 ubc-6 ubc-6 CBG13119 CBG13119 cul-4 cul-4 hsp-4 hsp-4 bath-44 bath-44 such-1 such-1 zyg-11 zyg-11 ufd-2 ufd-2 CBG13581 CBG13581 pbs-1 pbs-1 maea-1 maea-1 ubxn-2 ubxn-2 CBG14039 CBG14039 CBG14070 CBG14070 mans-3 mans-3 CBG14875 CBG14875 CBG14876 CBG14876 CBG15203 CBG15203 CBG15156 CBG15156 par-2 par-2 ubc-21 ubc-21 ubc-22 ubc-22 CBG15626 CBG15626 CBG15682 CBG15682 CBG15717 CBG15717 ubc-20 ubc-20 CBG15775 CBG15775 CBG15796 CBG15796 CBG16425 CBG16425 CBG16422 CBG16422 fbxl-1 fbxl-1 bath-42 bath-42 bath-41 bath-41 CBG16572 CBG16572 CBG16582 CBG16582 CBG16929 CBG16929 CBG16930 CBG16930 CBG17039 CBG17039 CBG17038 CBG17038 rle-1 rle-1 cul-2 cul-2 cul-1 cul-1 CBG18387 CBG18387 CBG17987 CBG17987 CBG17991 CBG17991 apc-11 apc-11 ubxn-4 ubxn-4 fsn-1 fsn-1 ubc-12 ubc-12 ubxn-5 ubxn-5 bath-40 bath-40 ubc-16 ubc-16 fem-1 fem-1 CBG20167 CBG20167 rnf-121 rnf-121 csa-1 csa-1 CBG20927 CBG20927 CBG21481 CBG21481 mans-4 mans-4 rpn-7 rpn-7 CBG21953 CBG21953 CBG22256 CBG22256 Cbr-grd-16 Cbr-grd-16 CBG22694 CBG22694 CBG22716 CBG22716 vms-1 vms-1 CBG22962 CBG22962 sel-1 sel-1 CBG23361 CBG23361 rpt-1 rpt-1 sel-11 sel-11 CBG25770 CBG25770 CBG26735 CBG26735 CBG26965 CBG26965 CBG25600 CBG25600 CBG25469 CBG25469 CBG25264 CBG25264 CBG27741 CBG27741 CBG27680 CBG27680 CBG27979 CBG27979 Cbr-spsb-2 Cbr-spsb-2 CBG20339 CBG20339 hsp-3 hsp-3 crt-1 crt-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG23907Protein CBG23907. (101 aa)
CBG23920Protein CBG23920; Belongs to the AAA ATPase family. (268 aa)
rpn-11Protein CBR-RPN-11. (312 aa)
rpn-226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa)
srh-186Protein CBR-SRH-186. (330 aa)
CBG24312Protein CBG24312. (284 aa)
Cbr-gadr-3Protein CBR-GADR-3. (662 aa)
ubc-1Protein CBR-UBC-1; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
CBG24536Protein CBG24536. (118 aa)
CBG24537Protein CBG24537. (266 aa)
CBG24538Protein CBG24538. (438 aa)
fzr-1Protein CBR-FZR-1. (708 aa)
CBG00481Protein CBG00481. (126 aa)
Cbr-skr-10Protein CBR-SKR-10; Belongs to the SKP1 family. (196 aa)
CBG00496Protein CBG00496; Belongs to the SKP1 family. (198 aa)
CBG00499Protein CBG00499. (483 aa)
cdc-48.2Protein CBG00746; Belongs to the AAA ATPase family. (811 aa)
emb-27Protein CBR-EMB-27. (669 aa)
CBG00586Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (161 aa)
usp-14Ubiquitin carboxyl-terminal hydrolase. (489 aa)
ufd-3Protein CBR-UFD-3. (896 aa)
CBG00897Protein CBG00897. (589 aa)
CBG01819Protein CBG01819. (418 aa)
CBG01952alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (954 aa)
CBG02109Protein CBG02109. (482 aa)
CBG02202Protein CBG02202; Belongs to the SKP1 family. (174 aa)
cup-2Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (245 aa)
cdc-48.1Protein CBG03070; Belongs to the AAA ATPase family. (865 aa)
mat-2Protein CBR-MAT-2. (1853 aa)
rpn-12Protein CBR-RPN-12. (250 aa)
CBG02791Protein CBG02791. (267 aa)
fzy-1Protein CBR-FZY-1. (521 aa)
CBG02414Protein CBG02414; Belongs to the SKP1 family. (284 aa)
CBG02386Protein CBG02386. (738 aa)
pbs-3Proteasome subunit beta. (204 aa)
sgt-1Protein CBR-SGT-1. (339 aa)
ufd-1Protein CBR-UFD-1. (341 aa)
eel-1Protein CBR-EEL-1. (4188 aa)
CBG03437alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (568 aa)
CBG03913Protein CBG03913. (215 aa)
CBG04230Protein CBG04230. (186 aa)
skr-1Protein CBR-SKR-1; Belongs to the SKP1 family. (172 aa)
CBG04254Protein CBG04254. (80 aa)
CBG04283E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1903 aa)
CBG04287E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (187 aa)
rpn-5Protein CBR-RPN-5. (491 aa)
CBG04755Protein CBG04755. (154 aa)
CBG04772Protein CBG04772; Belongs to the AAA ATPase family. (426 aa)
CBG04780Protein CBG04780. (428 aa)
wwp-1E3 ubiquitin-protein ligase. (794 aa)
skpt-1Protein CBR-SKPT-1. (418 aa)
CBG05191Protein CBG05191. (903 aa)
skr-20Protein CBR-SKR-20; Belongs to the SKP1 family. (165 aa)
skr-19Protein CBR-SKR-19; Belongs to the SKP1 family. (162 aa)
skr-21Protein CBR-SKR-21; Belongs to the SKP1 family. (166 aa)
ddb-1Protein CBR-DDB-1. (1134 aa)
dnj-1Protein CBR-DNJ-1. (398 aa)
enpl-1Protein CBG06014. (776 aa)
skr-16Protein CBR-SKR-16; Belongs to the SKP1 family. (181 aa)
CBG05790Protein CBG05790. (183 aa)
hecd-1Protein CBR-HECD-1. (2727 aa)
rpn-126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (992 aa)
CBG06331Protein CBG06331. (813 aa)
Cbr-tag-304Protein CBR-TAG-304. (397 aa)
CBG06669Protein CBG06669. (677 aa)
nhl-1Protein CBR-NHL-1. (979 aa)
CBG06886Protein CBG06886. (583 aa)
CBG07183Protein CBG07183. (780 aa)
ubxn-3Protein CBR-UBXN-3. (592 aa)
rpt-4Protein CBR-RPT-4; Belongs to the AAA ATPase family. (398 aa)
CBG07636Protein CBG07636. (460 aa)
gfi-3Protein CBR-GFI-3. (794 aa)
ubc-14Protein CBR-UBC-14; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
grd-15Protein CBR-GRD-15. (265 aa)
siah-1E3 ubiquitin-protein ligase siah-1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates; Belongs to the SINA (Seven in absentia) family. (434 aa)
CBG08535Protein CBG08535. (576 aa)
CBG08732Protein CBG08732. (351 aa)
CBG08741Protein CBG08741. (519 aa)
CBG08898Protein CBG08898; Belongs to the SKP1 family. (161 aa)
rpt-3Protein CBR-RPT-3; Belongs to the AAA ATPase family. (417 aa)
CBG09040Protein CBG09040; Belongs to the SKP1 family. (186 aa)
madf-11Protein CBR-MADF-11. (531 aa)
CBG09125Protein CBG09125; Belongs to the SKP1 family. (197 aa)
CBG09126Protein CBG09126; Belongs to the SKP1 family. (203 aa)
CBG09205Protein CBG09205. (370 aa)
apc-10Protein CBR-APC-10. (144 aa)
cul-5Protein CBR-CUL-5; Belongs to the cullin family. (766 aa)
rpt-2Protein CBR-RPT-2; Belongs to the AAA ATPase family. (443 aa)
Cbr-jamp-1Protein CBR-JAMP-1. (541 aa)
CBG09804Protein CBG09804. (232 aa)
hecw-1Protein CBR-HECW-1. (920 aa)
CBG09885Protein CBG09885. (68 aa)
bath-43Protein CBR-BATH-43. (459 aa)
cnx-1Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death (By similarity). (623 aa)
ubc-7Protein CBR-UBC-7; Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
ubql-1Protein CBG10788. (525 aa)
mat-1Protein CBR-MAT-1. (746 aa)
CBG10989Protein CBG10989; Belongs to the SKP1 family. (208 aa)
CBG10845Protein CBG10845. (624 aa)
CBG11069Protein CBG11069; Belongs to the AAA ATPase family. (438 aa)
aip-1Protein CBR-AIP-1. (204 aa)
cdt-2Protein CBR-CDT-2. (699 aa)
CBG11722Protein CBG11722. (919 aa)
rpt-6Protein CBR-RPT-6; Belongs to the AAA ATPase family. (417 aa)
ubr-1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2072 aa)
rpn-8Protein CBR-RPN-8. (382 aa)
CBG11949Protein CBG11949; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
wdr-23DDB1- and CUL4-associated factor 11 homolog; Involved in regulation of lifespan. Required for dopaminergic CEP neuron degeneration in response to Mn(2+). (554 aa)
marc-6Protein CBR-MARC-6. (1097 aa)
CBG12265Protein CBG12265. (1901 aa)
mel-26Protein CBR-MEL-26. (394 aa)
rpn-10Protein CBR-RPN-10. (347 aa)
rpt-5Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa)
chn-1Protein CBR-CHN-1. (266 aa)
mat-3Protein CBR-MAT-3. (667 aa)
skr-17Protein CBR-SKR-17; Belongs to the SKP1 family. (177 aa)
CBG12958Protein CBG12958; Belongs to the SKP1 family. (161 aa)
ubc-6Protein CBR-UBC-6. (317 aa)
CBG13119Protein CBG13119. (151 aa)
cul-4Protein CBR-CUL-4; Belongs to the cullin family. (867 aa)
hsp-4Protein CBR-HSP-4; Belongs to the heat shock protein 70 family. (655 aa)
bath-44Protein CBR-BATH-44. (389 aa)
such-1Protein CBR-SUCH-1. (769 aa)
zyg-11Protein CBR-ZYG-11. (807 aa)
ufd-2Protein CBR-UFD-2. (1035 aa)
CBG13581Protein CBG13581. (651 aa)
pbs-1Proteasome subunit beta. (239 aa)
maea-1Protein CBR-MAEA-1. (424 aa)
ubxn-2Protein CBR-UBXN-2. (702 aa)
CBG14039Protein CBG14039. (1159 aa)
CBG14070Protein CBG14070. (283 aa)
mans-3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (589 aa)
CBG14875Protein CBG14875; Belongs to the SKP1 family. (154 aa)
CBG14876Protein CBG14876; Belongs to the SKP1 family. (149 aa)
CBG15203Protein CBG15203. (648 aa)
CBG15156Protein CBG15156; Belongs to the SKP1 family. (335 aa)
par-2Protein CBR-PAR-2. (647 aa)
ubc-21Protein CBR-UBC-21; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
ubc-22Protein CBR-UBC-22. (200 aa)
CBG15626Protein CBG15626; Belongs to the SKP1 family. (208 aa)
CBG15682Protein CBG15682. (462 aa)
CBG15717Protein CBG15717. (539 aa)
ubc-20Protein CBR-UBC-20; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
CBG15775Protein CBG15775. (224 aa)
CBG15796Protein CBG15796. (881 aa)
CBG16425Protein CBG16425. (528 aa)
CBG16422Protein CBG16422. (1450 aa)
fbxl-1Protein CBG16659. (465 aa)
bath-42Protein CBR-BATH-42. (162 aa)
bath-41Protein CBR-BATH-41. (419 aa)
CBG16572Protein CBG16572. (324 aa)
CBG16582Protein CBG16582. (228 aa)
CBG16929Protein CBG16929. (126 aa)
CBG16930Protein CBG16930. (204 aa)
CBG17039Protein CBG17039; Belongs to the cullin family. (719 aa)
CBG17038Protein CBG17038; Belongs to the cullin family. (771 aa)
rle-1Protein CBR-RLE-1. (1001 aa)
cul-2Protein CBR-CUL-2; Belongs to the cullin family. (850 aa)
cul-1Protein CBR-CUL-1; Belongs to the cullin family. (768 aa)
CBG18387Protein CBG18387. (1807 aa)
CBG17987Protein CBG17987. (265 aa)
CBG17991Protein CBG17991. (622 aa)
apc-11Protein CBR-APC-11. (134 aa)
ubxn-4Protein CBR-UBXN-4. (456 aa)
fsn-1F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
ubc-12Protein CBR-UBC-12; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
ubxn-5Protein CBR-UBXN-5. (206 aa)
bath-40Protein CBR-BATH-40. (399 aa)
ubc-16Protein CBR-UBC-16. (148 aa)
fem-1Protein CBR-FEM-1. (660 aa)
CBG20167Protein CBG20167. (530 aa)
rnf-121Protein CBR-RNF-121. (332 aa)
csa-1Protein CBG20232. (348 aa)
CBG20927Protein CBG20927. (1176 aa)
CBG21481Protein CBG21481. (125 aa)
mans-4alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (527 aa)
rpn-7Protein CBR-RPN-7. (409 aa)
CBG21953Protein CBG21953. (1111 aa)
CBG22256E3 ubiquitin-protein ligase. (759 aa)
Cbr-grd-16Protein CBR-GRD-16. (433 aa)
CBG22694Protein CBG22694. (552 aa)
CBG22716Protein CBG22716. (460 aa)
vms-1Protein CBR-VMS-1. (648 aa)
CBG22962Protein CBG22962. (399 aa)
sel-1Protein CBR-SEL-1. (685 aa)
CBG23361alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (775 aa)
rpt-1Protein CBR-RPT-1; Belongs to the AAA ATPase family. (435 aa)
sel-11E3 ubiquitin-protein ligase hrd-1; Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated ubc-7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system, which is also called the ER-associated degradation (ERAD) system, involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins. Protects cells from ER stress-induced apoptosis. Thought to play [...] (622 aa)
CBG25770Protein CBG25770. (499 aa)
CBG26735Protein CBG26735. (328 aa)
CBG26965Protein CBG26965. (283 aa)
CBG25600Protein CBG25600. (155 aa)
CBG25469Protein CBG25469. (244 aa)
CBG25264E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to vcp/p97 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family. (1503 aa)
CBG27741Protein CBG27741; Belongs to the cullin family. (134 aa)
CBG27680Protein CBG27680. (239 aa)
CBG27979Protein CBG27979. (436 aa)
Cbr-spsb-2Protein CBR-SPSB-2. (493 aa)
CBG20339Protein CBG20339; Belongs to the AAA ATPase family. (415 aa)
hsp-3Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. (661 aa)
crt-1Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress- induced neurodegeneration (By similarity). (396 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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