(61 nodes) Membrane raft network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cav-2	Protein CBR-CAV-2. (275 aa)
	tre-2	Trehalase. (600 aa)
	ctsa-2	Carboxypeptidase; Belongs to the peptidase S10 family. (2261 aa)
	CBG04326	Protein CBG04326. (862 aa)
	vps-32.1	Protein CBR-VPS-32.1. (222 aa)
	ctsa-1.1	Carboxypeptidase; Belongs to the peptidase S10 family. (467 aa)
	pho-12	Protein CBG02310; Belongs to the histidine acid phosphatase family. (492 aa)
	pho-1	Protein CBR-PHO-1; Belongs to the histidine acid phosphatase family. (447 aa)
	pho-4	Protein CBR-PHO-4; Belongs to the histidine acid phosphatase family. (448 aa)
	lec-5	Galectin. (314 aa)
	ctsa-4.1	Carboxypeptidase; Belongs to the peptidase S10 family. (471 aa)
	lec-1	Galectin. (279 aa)
	pho-13	Protein CBG03178; Belongs to the histidine acid phosphatase family. (449 aa)
	CBG02162	Protein CBG02162. (372 aa)
	CBG00997	Protein CBG00997; Belongs to the histidine acid phosphatase family. (723 aa)
	pho-11	Protein CBG01002; Belongs to the histidine acid phosphatase family. (433 aa)
	nep-22	Protein CBG00200. (859 aa)
	stl-1	Protein CBR-STL-1. (323 aa)
	CBG24445	Protein CBG24445. (368 aa)
	CBG24443	Protein CBG24443. (93 aa)
	CBG23668	Protein CBG23668. (439 aa)
	CBG29119	Protein CBG29119. (274 aa)
	spe-4	Protein CBR-SPE-4. (483 aa)
	CBG11495	Protein CBG11495. (465 aa)
	lmtr-5	Protein CBG25826. (95 aa)
	CBG27002	Protein CBG27002. (99 aa)
	act-4	Protein CBG23090. (376 aa)
	lmtr-3	Protein CBG23109. (147 aa)
	tre-3	Trehalase. (608 aa)
	Cbr-tag-10	Protein CBR-TAG-10. (451 aa)
	unc-5	Protein CBR-UNC-5. (922 aa)
	Cbr-gfi-1	Protein CBR-GFI-1. (2435 aa)
	ctsa-4.2	Carboxypeptidase; Belongs to the peptidase S10 family. (665 aa)
	cav-1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
	CBG14660	Protein CBG14660. (511 aa)
	pcp-3	Protein CBR-PCP-3. (1114 aa)
	CBG21794	Protein CBG21794. (1094 aa)
	vha-19	Protein CBR-VHA-19. (453 aa)
	nep-17	Protein CBG20766. (1613 aa)
	CBG14574	Protein CBG14574. (324 aa)
	hpo-6	Protein CBR-HPO-6. (456 aa)
	CBG13527	Protein CBG13527. (212 aa)
	lec-2	Galectin. (322 aa)
	CBG13378	Protein CBG13378. (500 aa)
	ctsa-3.1	Carboxypeptidase; Belongs to the peptidase S10 family. (573 aa)
	CBG12171	Protein CBG12171. (424 aa)
	CBG12168	Protein CBG12168. (393 aa)
	hop-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
	lmtr-2	Protein CBG11395. (124 aa)
	CBG11487	Protein CBG11487. (454 aa)
	CBG11490	Protein CBG11490. (488 aa)
	dct-17	Protein CBR-DCT-17. (657 aa)
	vha-1	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (166 aa)
	CBG09578	Protein CBG09578. (387 aa)
	lec-4	Galectin. (283 aa)
	sli-1	Protein CBR-SLI-1. (546 aa)
	CBG08099	Protein CBG08099. (560 aa)
	sel-12	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
	CBG07404	Protein CBG07404. (214 aa)
	CBG07588	Carboxypeptidase; Belongs to the peptidase S10 family. (2203 aa)
	tre-5	Trehalase. (687 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG04326	CBG11487	A8WX95	A8XCW3	Protein CBG04326.	Protein CBG11487.	0.668
CBG04326	CBG11490	A8WX95	A8XCW0	Protein CBG04326.	Protein CBG11490.	0.710
CBG07588	ctsa-2	A8X4H8	A8WZ31	Carboxypeptidase; Belongs to the peptidase S10 family.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.418
CBG07588	nep-17	A8X4H8	A8XYK3	Carboxypeptidase; Belongs to the peptidase S10 family.	Protein CBG20766.	0.773
CBG07588	nep-22	A8X4H8	A8WMG5	Carboxypeptidase; Belongs to the peptidase S10 family.	Protein CBG00200.	0.591
CBG08099	CBG14660	A8X5T4	A8XKE1	Protein CBG08099.	Protein CBG14660.	0.462
CBG08099	ctsa-2	A8X5T4	A8WZ31	Protein CBG08099.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.697
CBG08099	ctsa-4.1	A8X5T4	A8WTU9	Protein CBG08099.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.650
CBG08099	ctsa-4.2	A8X5T4	A8XLQ2	Protein CBG08099.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.669
CBG11487	CBG04326	A8XCW3	A8WX95	Protein CBG11487.	Protein CBG04326.	0.668
CBG11490	CBG04326	A8XCW0	A8WX95	Protein CBG11490.	Protein CBG04326.	0.710
CBG12168	Cbr-gfi-1	A8XEX0	A8XUD1	Protein CBG12168.	Protein CBR-GFI-1.	0.625
CBG13527	vha-19	A8XI37	A8XZB4	Protein CBG13527.	Protein CBR-VHA-19.	0.461
CBG14660	CBG08099	A8XKE1	A8X5T4	Protein CBG14660.	Protein CBG08099.	0.462
CBG14660	ctsa-2	A8XKE1	A8WZ31	Protein CBG14660.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.774
CBG14660	ctsa-4.1	A8XKE1	A8WTU9	Protein CBG14660.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.670
CBG14660	ctsa-4.2	A8XKE1	A8XLQ2	Protein CBG14660.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.685
CBG14660	nep-22	A8XKE1	A8WMG5	Protein CBG14660.	Protein CBG00200.	0.424
CBG24443	CBG29119	A8WKQ4	H8WHC9	Protein CBG24443.	Protein CBG29119.	0.921
CBG29119	CBG24443	H8WHC9	A8WKQ4	Protein CBG29119.	Protein CBG24443.	0.921