STRINGSTRING
Cbr-gadr-3 Cbr-gadr-3 him-14 him-14 zhp-4 zhp-4 CBG00341 CBG00341 msh-5 msh-5 CBG01590 CBG01590 him-3 him-3 rmh-1 rmh-1 szy-20 szy-20 xpf-1 xpf-1 CBG02957 CBG02957 top-2 top-2 ify-1 ify-1 syp-1 syp-1 dpy-26 dpy-26 CBG03418 CBG03418 tim-1 tim-1 cep-1 cep-1 htp-3 htp-3 lem-3 lem-3 lab-1 lab-1 scc-1 scc-1 eme-1 eme-1 spd-3 spd-3 cyb-3 cyb-3 CBG07183 CBG07183 pqn-85 pqn-85 scc-3 scc-3 him-10 him-10 gcna-1 gcna-1 plk-1 plk-1 syp-2 syp-2 CBG09703 CBG09703 him-17 him-17 bub-1 bub-1 CBG11554 CBG11554 pph-4.1 pph-4.1 Cbr-coh-4 Cbr-coh-4 capg-1 capg-1 CBG12030 CBG12030 rec-8 rec-8 CBG12075 CBG12075 gei-17 gei-17 zhp-1 zhp-1 zhp-3 zhp-3 zhp-2 zhp-2 mut-2 mut-2 san-1 san-1 Cbr-zim-1 Cbr-zim-1 CBG12897 CBG12897 him-8 him-8 spe-6 spe-6 zyg-11 zyg-11 eri-1 eri-1 fcd-2 fcd-2 CBG14893 CBG14893 sep-1 sep-1 helq-1 helq-1 CBG15297 CBG15297 rfs-1 rfs-1 CBG16929 CBG16929 CBG16930 CBG16930 cul-2 cul-2 apc-11 apc-11 evl-14 evl-14 CBG18156 CBG18156 CBG19180 CBG19180 atl-1 atl-1 rbx-1 rbx-1 rmh-2 rmh-2 csc-1 csc-1 CBG20864 CBG20864 Cbr-gsp-4 Cbr-gsp-4 him-6 him-6 CBG21913 CBG21913 rde-2 rde-2 syp-3 syp-3 CBG22694 CBG22694 CBG25469 CBG25469 CBG27313 CBG27313 dpy-28 dpy-28 sgo-1 sgo-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cbr-gadr-3Protein CBR-GADR-3. (662 aa)
him-14Protein CBR-HIM-14. (771 aa)
zhp-4Protein CBG24873. (246 aa)
CBG00341Protein CBG00341. (291 aa)
msh-5Protein CBR-MSH-5. (1332 aa)
CBG01590Protein CBG01590. (79 aa)
him-3Protein CBR-HIM-3. (235 aa)
rmh-1Protein CBG02237. (944 aa)
szy-20Protein CBR-SZY-20. (514 aa)
xpf-1Protein CBG03141. (927 aa)
CBG02957Protein CBG02957. (364 aa)
top-2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1482 aa)
ify-1Protein CBR-IFY-1. (281 aa)
syp-1Protein CBR-SYP-1. (494 aa)
dpy-26Protein CBR-DPY-26. (1261 aa)
CBG03418Protein CBG03418. (276 aa)
tim-1Protein CBR-TIM-1. (1404 aa)
cep-1Transcription factor cep-1; Transcriptional activator that binds the same DNA consensus sequence as p53. Has a role in normal development to ensure proper meiotic chromosome segregation. Promotes apoptosis under conditions of cellular and genotoxic stress in response to DNA damage, hypoxia, or starvation. However, not required for DNA repair in response to UV-C or to regulate cell-cycle progression. Regulates germline apoptosis in response to DNA damage. Required for induction of ced-13 in response to DNA damage. Its pro-apoptotic activity is inhibited when bound to ape-1 in vitro (By [...] (658 aa)
htp-3Protein CBR-HTP-3. (624 aa)
lem-3Protein CBR-LEM-3. (698 aa)
lab-1Protein CBR-LAB-1. (153 aa)
scc-1Protein CBR-SCC-1. (633 aa)
eme-1Protein CBG05147. (430 aa)
spd-3Protein CBG05380. (499 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
CBG07183Protein CBG07183. (780 aa)
pqn-85Nipped-B protein. (2140 aa)
scc-3Protein CBR-SCC-3. (1122 aa)
him-10Protein CBR-HIM-10. (637 aa)
gcna-1Protein CBG09024. (492 aa)
plk-1Serine/threonine-protein kinase PLK. (661 aa)
syp-2Protein CBR-SYP-2. (190 aa)
CBG09703Protein CBG09703. (277 aa)
him-17Protein CBR-HIM-17. (929 aa)
bub-1Protein CBR-BUB-1. (971 aa)
CBG11554Protein CBG11554. (266 aa)
pph-4.1Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] (333 aa)
Cbr-coh-4Protein CBR-COH-4. (667 aa)
capg-1Protein CBR-CAPG-1. (1270 aa)
CBG12030Protein CBG12030. (233 aa)
rec-8Protein CBR-REC-8. (844 aa)
CBG12075Protein CBG12075. (611 aa)
gei-17Protein CBR-GEI-17. (675 aa)
zhp-1Protein CBG12322. (69 aa)
zhp-3Protein CBR-ZHP-3. (394 aa)
zhp-2Protein CBG12534. (239 aa)
mut-2Protein CBR-MUT-2. (446 aa)
san-1Protein CBR-SAN-1. (390 aa)
Cbr-zim-1Protein CBR-ZIM-1. (579 aa)
CBG12897Protein CBG12897. (750 aa)
him-8Protein CBG12898. (487 aa)
spe-6Protein CBR-SPE-6. (796 aa)
zyg-11Protein CBR-ZYG-11. (807 aa)
eri-1Protein CBR-ERI-1. (578 aa)
fcd-2Protein CBR-FCD-2. (1431 aa)
CBG14893Protein CBG14893. (521 aa)
sep-1Protein CBR-SEP-1. (1265 aa)
helq-1Protein CBG15258. (913 aa)
CBG15297Protein CBG15297. (314 aa)
rfs-1RAD51-like protein 1; Has a role in the homologous recombination repair (HRR) of genomic DNA during meiosis. Required for rad-51 recruitment onto ssDNA gaps generated at stalled replication fork barriers (By similarity). (244 aa)
CBG16929Protein CBG16929. (126 aa)
CBG16930Protein CBG16930. (204 aa)
cul-2Protein CBR-CUL-2; Belongs to the cullin family. (850 aa)
apc-11Protein CBR-APC-11. (134 aa)
evl-14Protein CBR-EVL-14. (1690 aa)
CBG18156DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1207 aa)
CBG19180Protein CBG19180. (387 aa)
atl-1Protein CBR-ATL-1; Belongs to the PI3/PI4-kinase family. (2556 aa)
rbx-1Protein CBR-RBX-1. (110 aa)
rmh-2Protein CBG19410. (602 aa)
csc-1Protein CBR-CSC-1. (204 aa)
CBG20864Protein CBG20864. (355 aa)
Cbr-gsp-4Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (242 aa)
him-6Protein CBR-HIM-6. (1005 aa)
CBG21913Protein CBG21913. (618 aa)
rde-2Protein CBR-RDE-2. (709 aa)
syp-3Protein CBR-SYP-3. (216 aa)
CBG22694Protein CBG22694. (552 aa)
CBG25469Protein CBG25469. (244 aa)
CBG27313Protein CBG27313. (449 aa)
dpy-28Protein CBG25999. (1510 aa)
sgo-1Shugoshin; Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms; Belongs to the shugoshin family. (306 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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