(60 nodes) Basal part of cell network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdh-3	Protein CBR-CDH-3. (3207 aa)
	nid-1	Protein CBR-NID-1. (1590 aa)
	mics-1	Protein CBR-MICS-1. (292 aa)
	par-3	Protein CBR-PAR-3. (1332 aa)
	let-413	Protein CBR-LET-413. (702 aa)
	lgl-1	Protein CBR-LGL-1. (969 aa)
	mrp-5	Protein CBR-MRP-5. (1439 aa)
	fgt-1	Protein CBR-FGT-1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (537 aa)
	aqp-3	Protein CBR-AQP-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (419 aa)
	gtl-2	Protein CBR-GTL-2. (1443 aa)
	num-1	Protein CBR-NUM-1. (636 aa)
	cdf-1	Protein CBR-CDF-1. (545 aa)
	slcf-1	Protein CBR-SLCF-1. (450 aa)
	itx-1	Protein CBR-ITX-1. (1634 aa)
	pat-3	Integrin beta; Belongs to the integrin beta chain family. (818 aa)
	unc-64	Syntaxin-1A; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent s [...] (293 aa)
	abts-3	Protein CBR-ABTS-3. (1016 aa)
	myrf-1	Protein CBR-PQN-47. (925 aa)
	vang-1	Vang-like protein. (532 aa)
	tsp-21	Tetraspanin. (298 aa)
	let-23	Receptor protein-tyrosine kinase. (1379 aa)
	aqp-2	Protein CBR-AQP-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (289 aa)
	cnnm-1	Protein CBG00360. (801 aa)
	arf-6	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	CBG10300	Protein CBG10300. (675 aa)
	alp-1	Protein CBR-ALP-1. (2170 aa)
	cls-3	Protein CLASP-3; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules; Belongs to the CLASP family. (970 aa)
	CBG09173	Protein CLASP-1; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules; Belongs to the CLASP family. (1333 aa)
	cls-2	Protein CLASP-2; Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming (By similarity). (791 aa)
	alx-1	Protein CBR-ALX-1, isoform a. (893 aa)
	CBG25885	Protein CBG25885. (307 aa)
	pat-6	Protein CBR-PAT-6. (379 aa)
	cpna-1	Protein CBR-CPNA-1. (1075 aa)
	cnt-1	Protein CBR-CNT-1. (824 aa)
	aqp-12	Protein CBR-AQP-12; Belongs to the MIP/aquaporin (TC 1.A.8) family. (211 aa)
	mig-14	Protein CBR-MIG-14. (548 aa)
	sulp-8	Protein CBR-SULP-8. (614 aa)
	dgn-1	Protein CBR-DGN-1. (594 aa)
	pbo-4	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
	abts-2	Protein CBR-ABTS-2. (754 aa)
	unc-115	Protein CBR-UNC-115. (623 aa)
	toca-1	Protein CBR-TOCA-1. (588 aa)
	CBG15811	Protein CBG15811. (3870 aa)
	Cbr-pat-4	Protein CBR-PAT-4. (278 aa)
	pat-12	Protein CBR-PAT-12. (708 aa)
	sulp-2	Protein CBR-SULP-2. (810 aa)
	unc-97	LIM domain-containing protein. (353 aa)
	dlg-1	Protein CBR-DLG-1; Belongs to the MAGUK family. (1015 aa)
	aqp-8	Protein CBR-AQP-8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
	lin-18	Protein CBR-LIN-18. (599 aa)
	cnnm-3	Protein CBG14121. (417 aa)
	aqp-7	Protein CBR-AQP-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (302 aa)
	dsc-4	Protein CBR-DSC-4. (914 aa)
	maa-1	Protein CBR-MAA-1. (280 aa)
	aqp-1	Protein CBR-AQP-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (300 aa)
	hmit-1.2	Protein CBR-HMIT-1.2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (615 aa)
	sup-17	Protein CBR-SUP-17. (920 aa)
	tat-1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1218 aa)
	lin-7	Protein CBR-LIN-7. (316 aa)
	abts-4	Protein CBR-ABTS-4. (1013 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG10300	arf-6	A8XAN5	A8WMU9	Protein CBG10300.	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	0.402
CBG10300	dlg-1	A8XAN5	A8XKG7	Protein CBG10300.	Protein CBR-DLG-1; Belongs to the MAGUK family.	0.444
CBG10300	lin-7	A8XAN5	A8XCE8	Protein CBG10300.	Protein CBR-LIN-7.	0.493
CBG15811	dlg-1	A8XMZ0	A8XKG7	Protein CBG15811.	Protein CBR-DLG-1; Belongs to the MAGUK family.	0.478
CBG15811	pat-3	A8XMZ0	A8WVF5	Protein CBG15811.	Integrin beta; Belongs to the integrin beta chain family.	0.681
Cbr-pat-4	pat-3	A8XMT5	A8WVF5	Protein CBR-PAT-4.	Integrin beta; Belongs to the integrin beta chain family.	0.995
Cbr-pat-4	pat-6	A8XMT5	A8Y2J2	Protein CBR-PAT-4.	Protein CBR-PAT-6.	0.999
Cbr-pat-4	unc-97	A8XMT5	A8XKH8	Protein CBR-PAT-4.	LIM domain-containing protein.	0.999
abts-4	lin-7	A8XC73	A8XCE8	Protein CBR-ABTS-4.	Protein CBR-LIN-7.	0.633
abts-4	par-3	A8XC73	A8X828	Protein CBR-ABTS-4.	Protein CBR-PAR-3.	0.523
alp-1	pat-3	A8WKA2	A8WVF5	Protein CBR-ALP-1.	Integrin beta; Belongs to the integrin beta chain family.	0.709
alp-1	pat-6	A8WKA2	A8Y2J2	Protein CBR-ALP-1.	Protein CBR-PAT-6.	0.622
alx-1	arf-6	H8WHA2	A8WMU9	Protein CBR-ALX-1, isoform a.	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	0.492
arf-6	CBG10300	A8WMU9	A8XAN5	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Protein CBG10300.	0.402
arf-6	alx-1	A8WMU9	H8WHA2	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Protein CBR-ALX-1, isoform a.	0.492
arf-6	cnt-1	A8WMU9	A8XZ59	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Protein CBR-CNT-1.	0.610
arf-6	let-23	A8WMU9	A8WPC3	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Receptor protein-tyrosine kinase.	0.402
arf-6	let-413	A8WMU9	A8X6Z6	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Protein CBR-LET-413.	0.432
arf-6	num-1	A8WMU9	A8X063	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	Protein CBR-NUM-1.	0.573
cnt-1	arf-6	A8XZ59	A8WMU9	Protein CBR-CNT-1.	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family.	0.610