STRINGSTRING
CBG00490 CBG00490 ctns-1 ctns-1 atg-18 atg-18 CBG01467 CBG01467 lgg-1 lgg-1 snx-1 snx-1 ocrl-1 ocrl-1 lmp-1 lmp-1 ina-1 ina-1 rab-14 rab-14 dyn-1 dyn-1 piki-1 piki-1 epn-1 epn-1 CBG07900 CBG07900 ced-6 ced-6 ccz-1 ccz-1 CBG11259 CBG11259 unc-108 unc-108 ced-1 ced-1 lst-4 lst-4 CBG19476 CBG19476 CBG20134 CBG20134 rab-7 rab-7 CBG22562 CBG22562 cpl-1 cpl-1 snx-6 snx-6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG00490Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (271 aa)
ctns-1Cystinosin homolog; Thought to transport cystine out of lysosomes. May play a role in the degradation of engulfed apoptotic cells (By similarity). Belongs to the cystinosin family. (403 aa)
atg-18Protein CBR-ATG-18. (406 aa)
CBG01467Protein CBG01467. (383 aa)
lgg-1Protein lgg. (123 aa)
snx-1Protein CBR-SNX-1. (472 aa)
ocrl-1Protein CBR-OCRL-1. (711 aa)
lmp-1Protein CBR-LMP-1. (252 aa)
ina-1Protein CBR-INA-1; Belongs to the integrin alpha chain family. (1147 aa)
rab-14Protein CBR-RAB-14. (210 aa)
dyn-1Protein CBR-DYN-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1440 aa)
piki-1Protein CBR-PIKI-1; Belongs to the PI3/PI4-kinase family. (1680 aa)
epn-1Protein CBR-EPN-1. (456 aa)
CBG07900Protein CBG07900. (409 aa)
ced-6Protein CBR-CED-6. (490 aa)
ccz-1Protein CBR-CCZ-1. (530 aa)
CBG11259Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (169 aa)
unc-108Protein CBR-UNC-108. (214 aa)
ced-1Cell death abnormality protein 1; Involved in programmed cell death/apoptosis. Acts by recruiting ced-6 to phagosomes which enables actin-dependent cytoskeletal reorganization and subsequent engulfment of the apoptotic cell corpse. Has a role in the association of ppk-3 and rab-7 with the phagosomal surface which is necessary for the incorporation of lysosomes to phagosomes during phagosome maturation. Activates the expression of unfolded protein response genes, which are involved in the immune response to live bacteria (By similarity). (1134 aa)
lst-4Sorting nexin; Belongs to the sorting nexin family. (595 aa)
CBG19476Protein CBG19476. (106 aa)
CBG20134Protein CBG20134; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (824 aa)
rab-7Protein CBR-RAB-7. (209 aa)
CBG22562Protein CBG22562. (355 aa)
cpl-1Protein CBR-CPL-1; Belongs to the peptidase C1 family. (336 aa)
snx-6Protein CBR-SNX-6. (838 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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