STRINGSTRING
CBG11069 CBG11069 CBG11124 CBG11124 CBG11130 CBG11130 eor-1 eor-1 rpt-6 rpt-6 daf-16 daf-16 rpt-5 rpt-5 chn-1 chn-1 zyg-11 zyg-11 ufd-2 ufd-2 ubxn-2 ubxn-2 CBG14615 CBG14615 sft-4 sft-4 zer-1 zer-1 CBG16148 CBG16148 CBG16793 CBG16793 CBG16929 CBG16929 CBG16930 CBG16930 CBG17760 CBG17760 pdr-1 pdr-1 CBG18064 CBG18064 prde-1 prde-1 pry-1 pry-1 CBG19675 CBG19675 ari-2 ari-2 ivd-1 ivd-1 kin-19 kin-19 oaz-1 oaz-1 ari-1.1 ari-1.1 CBG20695 CBG20695 mpk-1 mpk-1 CBG21263 CBG21263 CBG21463 CBG21463 CBG22557 CBG22557 CBG22694 CBG22694 CBG22695 CBG22695 CBG26705 CBG26705 CBG22697 CBG22697 CBG22707 CBG22707 rpt-1 rpt-1 CBG23632 CBG23632 CBG25469 CBG25469 CBG26587 CBG26587 CBG26997 CBG26997 CBG26170 CBG26170 CBG20339 CBG20339 CBG23920 CBG23920 Cbr-gadr-3 Cbr-gadr-3 fzr-1 fzr-1 CBG00082 CBG00082 CBG00534 CBG00534 CBG00506 CBG00506 let-23 let-23 CBG00902 CBG00902 cdc-48.1 cdc-48.1 sma-6 sma-6 fzy-1 fzy-1 acs-19 acs-19 CBG03663 CBG03663 ubxn-1 ubxn-1 CBG04772 CBG04772 hecd-1 hecd-1 CBG06887 CBG06887 CBG07183 CBG07183 CBG07145 CBG07145 CBG07143 CBG07143 CBG07133 CBG07133 ubxn-3 ubxn-3 rpt-4 rpt-4 nipi-3 nipi-3 CBG07264 CBG07264 gsk-3 gsk-3 aex-6 aex-6 CBG08098 CBG08098 swah-1 swah-1 apr-1 apr-1 rpt-3 rpt-3 sma-4 sma-4 CBG08978 CBG08978 cni-1 cni-1 rpt-2 rpt-2 CBG10274 CBG10274 CBG10273 CBG10273
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG11069Protein CBG11069; Belongs to the AAA ATPase family. (438 aa)
CBG11124Protein CBG11124. (812 aa)
CBG11130Protein CBG11130. (295 aa)
eor-1Protein CBR-EOR-1. (909 aa)
rpt-6Protein CBR-RPT-6; Belongs to the AAA ATPase family. (417 aa)
daf-16Protein CBR-DAF-16. (497 aa)
rpt-5Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa)
chn-1Protein CBR-CHN-1. (266 aa)
zyg-11Protein CBR-ZYG-11. (807 aa)
ufd-2Protein CBR-UFD-2. (1035 aa)
ubxn-2Protein CBR-UBXN-2. (702 aa)
CBG14615Protein CBG14615. (689 aa)
sft-4Protein CBR-SFT-4. (277 aa)
zer-1Protein CBR-ZER-1. (909 aa)
CBG16148Protein CBG16148. (505 aa)
CBG16793Protein CBG16793. (773 aa)
CBG16929Protein CBG16929. (126 aa)
CBG16930Protein CBG16930. (204 aa)
CBG17760RBR-type E3 ubiquitin transferase. (441 aa)
pdr-1E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (385 aa)
CBG18064Protein CBG18064. (987 aa)
prde-1Protein CBG18603. (553 aa)
pry-1Axin-like protein pry-1; Works in parallel with axl-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Inhibits Wnt signaling, which affects tissue specific expression of Hox genes, egl- 5, lin-39 and mab-5. This in turn affects QR (postembryonic neuroblast) cell migration, vulval cell fate specification, and the development of sensory structures by the seam cell lineage. Has a role in alae V cell patterning, ray formation in the male tail and axon guidance. Does not affect B cell polarity (By similarity). (625 aa)
CBG19675RBR-type E3 ubiquitin transferase. (460 aa)
ari-2RBR-type E3 ubiquitin transferase. (415 aa)
ivd-1Protein CBR-IVD-1. (417 aa)
kin-19Protein CBR-KIN-19; Belongs to the protein kinase superfamily. (342 aa)
oaz-1Protein CBG20259. (80 aa)
ari-1.1RBR-type E3 ubiquitin transferase. (494 aa)
CBG20695Protein CBG20695. (93 aa)
mpk-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
CBG21263RBR-type E3 ubiquitin transferase. (541 aa)
CBG21463Protein CBG21463. (562 aa)
CBG22557Protein CBG22557. (679 aa)
CBG22694Protein CBG22694. (552 aa)
CBG22695Protein CBG22695. (712 aa)
CBG26705Protein CBG26705. (108 aa)
CBG22697Protein CBG22697. (601 aa)
CBG22707RBR-type E3 ubiquitin transferase. (877 aa)
rpt-1Protein CBR-RPT-1; Belongs to the AAA ATPase family. (435 aa)
CBG23632Protein CBG23632. (169 aa)
CBG25469Protein CBG25469. (244 aa)
CBG26587Protein CBG26587. (599 aa)
CBG26997Protein CBG26997. (149 aa)
CBG26170Protein CBG26170. (87 aa)
CBG20339Protein CBG20339; Belongs to the AAA ATPase family. (415 aa)
CBG23920Protein CBG23920; Belongs to the AAA ATPase family. (268 aa)
Cbr-gadr-3Protein CBR-GADR-3. (662 aa)
fzr-1Protein CBR-FZR-1. (708 aa)
CBG00082Protein CBG00082. (740 aa)
CBG00534Protein CBG00534. (504 aa)
CBG00506Protein CBG00506. (343 aa)
let-23Receptor protein-tyrosine kinase. (1379 aa)
CBG00902Protein CBG00902. (599 aa)
cdc-48.1Protein CBG03070; Belongs to the AAA ATPase family. (865 aa)
sma-6Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (629 aa)
fzy-1Protein CBR-FZY-1. (521 aa)
acs-19Acetyl-coenzyme A synthetase. (680 aa)
CBG03663Protein CBG03663. (723 aa)
ubxn-1Protein CBR-UBXN-1. (305 aa)
CBG04772Protein CBG04772; Belongs to the AAA ATPase family. (426 aa)
hecd-1Protein CBR-HECD-1. (2727 aa)
CBG06887Protein CBG06887. (480 aa)
CBG07183Protein CBG07183. (780 aa)
CBG07145RBR-type E3 ubiquitin transferase. (474 aa)
CBG07143RBR-type E3 ubiquitin transferase. (557 aa)
CBG07133RBR-type E3 ubiquitin transferase. (403 aa)
ubxn-3Protein CBR-UBXN-3. (592 aa)
rpt-4Protein CBR-RPT-4; Belongs to the AAA ATPase family. (398 aa)
nipi-3Protein CBR-NIPI-3. (650 aa)
CBG07264Protein CBG07264. (300 aa)
gsk-3Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa)
aex-6Protein CBR-AEX-6. (215 aa)
CBG08098Protein CBG08098. (395 aa)
swah-1Protein CBG08199. (204 aa)
apr-1APC-related protein 1; Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing the polarity of the mother cel [...] (1171 aa)
rpt-3Protein CBR-RPT-3; Belongs to the AAA ATPase family. (417 aa)
sma-4Dwarfin sma. (603 aa)
CBG08978RBR-type E3 ubiquitin transferase. (498 aa)
cni-1Protein CBR-CNIH-2. (145 aa)
rpt-2Protein CBR-RPT-2; Belongs to the AAA ATPase family. (443 aa)
CBG10274Protein CBG10274. (86 aa)
CBG10273Protein CBG10273. (443 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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