STRINGSTRING
egl-3 egl-3 unc-104 unc-104 daf-16 daf-16 bli-4 bli-4 daf-2 daf-2 kpc-1 kpc-1 egl-21 egl-21 fsn-1 fsn-1 aex-5 aex-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
egl-3Protein CBR-EGL-3; Belongs to the peptidase S8 family. (662 aa)
unc-104Protein CBR-UNC-104; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1699 aa)
daf-16Protein CBR-DAF-16. (497 aa)
bli-4Protein CBR-BLI-4; Belongs to the peptidase S8 family. (730 aa)
daf-2Protein CBR-DAF-2. (1840 aa)
kpc-1Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
egl-21Protein CBR-EGL-21. (473 aa)
fsn-1F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
aex-5Protein CBR-AEX-5. (541 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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