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| | fem-3 | Sex-determination protein fem-3; Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite animals), it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. (409 aa) |
| | stl-1 | Protein CBR-STL-1. (323 aa) |
| | kars-1 | Lysine--tRNA ligase. (598 aa) |
| | daf-7 | Protein CBR-DAF-7. (376 aa) |
| | arf-6 | Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | CBG00445 | Protein CBG00445; Belongs to the protein kinase superfamily. Tyr protein kinase family. (440 aa) |
| | mop-25.2 | Protein CBR-MOP-25.2. (338 aa) |
| | let-23 | Receptor protein-tyrosine kinase. (1379 aa) |
| | CBG01733 | Protein CBG01733. (299 aa) |
| | CBG01732 | Protein CBG01732. (549 aa) |
| | tpa-1 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa) |
| | isp-1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa) |
| | CBG02222 | Protein CBG02222. (436 aa) |
| | CBG03052 | Protein CBG03052. (74 aa) |
| | ccm-3 | Protein CBG03050. (215 aa) |
| | rsf-1 | Protein CBG02930. (606 aa) |
| | gcn-2 | Protein CBG02792. (1692 aa) |
| | CBG02786 | Protein CBG02786. (805 aa) |
| | rict-1 | Protein CBG02784. (830 aa) |
| | CBG02319 | Protein CBG02319. (412 aa) |
| | nsy-1 | Protein CBR-NSY-1. (1577 aa) |
| | btbd-10 | Protein CBG02271. (568 aa) |
| | rack-1 | Protein CBR-RACK-1. (325 aa) |
| | CBG03606 | Protein CBG03606. (414 aa) |
| | CBG03609 | Protein CBG03609. (174 aa) |
| | tir-1 | Protein CBR-TIR-1. (585 aa) |
| | CBG03616 | Protein CBG03616. (379 aa) |
| | nepr-1 | Protein CBR-SPO-7. (138 aa) |
| | epg-8 | Protein CBR-EPG-8. (431 aa) |
| | icp-1 | Protein CBR-ICP-1. (516 aa) |
| | CBG04490 | Protein CBG04490. (696 aa) |
| | ccnk-1 | Protein CBG04574; Belongs to the cyclin family. (260 aa) |
| | CBG04848 | Protein CBG04848. (366 aa) |
| | CBG04906 | Protein CBG04906; Belongs to the protein kinase superfamily. Tyr protein kinase family. (458 aa) |
| | CBG04907 | Protein CBG04907. (385 aa) |
| | CBG04908 | Protein CBG04908. (372 aa) |
| | CBG04912 | Protein CBG04912. (283 aa) |
| | CBG04913 | Protein CBG04913. (401 aa) |
| | shc-1 | Protein CBR-SHC-1. (317 aa) |
| | CBG05171 | Protein CBG05171. (994 aa) |
| | nekl-4 | Protein CBR-NEKL-4. (1572 aa) |
| | CBG05239 | Protein CBG05239. (876 aa) |
| | mob-2 | Protein CBG05247. (357 aa) |
| | cyb-3 | Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa) |
| | par-4 | Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. Phosphorylates and regulates aak-2 in response to oxidative stress. May also play a role in motility, behavioral response, regulation of lifespan and dauer formation through this pathway (By similarity). (649 aa) |
| | mob-1 | Protein CBG06180. (193 aa) |
| | mob-3 | Protein CBG05852. (292 aa) |
| | CBG07665 | Protein CBG07665. (296 aa) |
| | tap-1 | Protein CBR-TAP-1. (389 aa) |
| | ncs-3 | Protein CBR-NCS-3. (174 aa) |
| | ncs-1 | Protein CBR-NCS-1. (191 aa) |
| | egl-17 | Protein CBR-EGL-17; Belongs to the heparin-binding growth factors family. (214 aa) |
| | vacl-14 | Protein CBG08220. (694 aa) |
| | mop-25.3 | MO25-like protein 3; Belongs to the Mo25 family. (492 aa) |
| | mlk-1 | Protein CBR-MLK-1. (1091 aa) |
| | tig-2 | Protein CBR-TIG-2. (364 aa) |
| | wrm-1 | Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa) |
| | ckk-1 | Protein CBR-CKK-1. (538 aa) |
| | hir-1 | Protein CBG09377. (1082 aa) |
| | tlk-1 | Protein CBR-TLK-1. (981 aa) |
| | CBG10068 | Protein CBG10068. (363 aa) |
| | CBG10300 | Protein CBG10300. (675 aa) |
| | hen-1 | Protein CBR-HEN-1. (118 aa) |
| | epg-7 | Protein CBR-ATG-11. (1313 aa) |
| | CBG10838 | Protein CBG10838. (249 aa) |
| | svh-2 | Protein CBG10839; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1120 aa) |
| | CBG11187 | Protein CBG11187. (719 aa) |
| | CBG11385 | Protein CBG11385. (307 aa) |
| | CBG12081 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (105 aa) |
| | rsa-1 | Protein CBR-RSA-1. (236 aa) |
| | CBG12411 | Protein CBG12411. (518 aa) |
| | tlf-1 | Protein CBR-TLF-1. (512 aa) |
| | sig-7 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (434 aa) |
| | CBG12570 | Protein CBG12570. (1945 aa) |
| | CBG12962 | Protein CBG12962. (351 aa) |
| | vab-1 | Protein CBR-VAB-1. (1118 aa) |
| | kin-15 | Protein CBR-KIN-15; Belongs to the protein kinase superfamily. Tyr protein kinase family. (506 aa) |
| | kin-16 | Protein CBR-KIN-16; Belongs to the protein kinase superfamily. Tyr protein kinase family. (501 aa) |
| | lem-4 | Protein CBG13985. (563 aa) |
| | CBG13871 | Protein CBG13871. (1063 aa) |
| | ddr-2 | Protein CBR-DDR-2. (898 aa) |
| | lin-18 | Protein CBR-LIN-18. (599 aa) |
| | CBG14320 | Protein CBG14320. (483 aa) |
| | mop-25.1 | Protein CBR-MOP-25.1. (615 aa) |
| | ddr-1 | Protein CBR-DDR-1. (821 aa) |
| | CBG14707 | Protein CBG14707. (591 aa) |
| | CBG15268 | Protein CBG15268. (765 aa) |
| | pvf-1 | Protein CBR-PVF-1. (300 aa) |
| | CBG15501 | Protein CBG15501. (583 aa) |
| | cks-1 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Has a role in the exit from M phase during early mitotic cell division. More specifically, thought to act by the degrading B-type cyclins that causes breakdown of nuclear envelope and exit mitosis (By similarity). (94 aa) |
| | CBG15645 | Protein CBG15645. (840 aa) |
| | daf-2 | Protein CBR-DAF-2. (1840 aa) |
| | CBG16626 | Protein CBG16626. (261 aa) |
| | cil-1 | Protein CBR-CIL-1. (398 aa) |
| | sek-1 | Protein CBR-SEK-1; Belongs to the protein kinase superfamily. (352 aa) |
| | clsp-1 | Protein CBG16944. (676 aa) |
| | pek-1 | Protein CBR-PEK-1. (1115 aa) |
| | CBG17534 | Protein CBG17534. (573 aa) |
| | CBG17535 | Receptor protein-tyrosine kinase. (1447 aa) |
| | ver-3 | Protein CBR-VER-3. (1313 aa) |
| | egl-15 | Receptor protein-tyrosine kinase. (1192 aa) |
| | strd-1 | Protein CBR-STRD-1. (385 aa) |
| | cdka-1 | Cyclin-dependent kinase 5 activator. (366 aa) |
| | cyy-1 | Protein CBR-CYY-1; Belongs to the cyclin family. (357 aa) |
| | pry-1 | Axin-like protein pry-1; Works in parallel with axl-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Inhibits Wnt signaling, which affects tissue specific expression of Hox genes, egl- 5, lin-39 and mab-5. This in turn affects QR (postembryonic neuroblast) cell migration, vulval cell fate specification, and the development of sensory structures by the seam cell lineage. Has a role in alae V cell patterning, ray formation in the male tail and axon guidance. Does not affect B cell polarity (By similarity). (625 aa) |
| | dbl-1 | Protein CBR-DBL-1. (373 aa) |
| | CBG19102 | Protein CBG19102. (1014 aa) |
| | CBG19566 | Protein CBG19566. (337 aa) |
| | let-756 | Protein CBR-LET-756; Belongs to the heparin-binding growth factors family. (473 aa) |
| | lars-1 | Protein CBR-LARS-1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1186 aa) |
| | cam-1 | Protein CBR-CAM-1. (916 aa) |
| | mnat-1 | Protein CBR-MNAT-1. (343 aa) |
| | tig-3 | Protein CBR-TIG-3. (225 aa) |
| | spat-1 | Protein CBR-SPAT-1. (542 aa) |
| | abcf-3 | Protein CBR-ABCF-3. (712 aa) |
| | clk-1 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa) |
| | unc-129 | Protein CBR-UNC-129. (404 aa) |
| | oma-2 | Protein CBR-OMA-2. (379 aa) |
| | daf-15 | Protein CBR-DAF-15. (1795 aa) |
| | rla-1 | Protein CBR-RLA-1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (111 aa) |
| | src-1 | Tyrosine-protein kinase. (544 aa) |
| | kin-9 | Protein CBR-KIN-9. (618 aa) |
| | CBG22965 | Protein CBG22965. (281 aa) |
| | cit-1.1 | Protein CBR-CIT-1.1. (161 aa) |
| | cit-1.2 | Protein CBR-CIT-1.2. (792 aa) |
| | CBG26435 | Protein CBG26435. (290 aa) |
| | CBG27553 | Protein CBG27553. (89 aa) |
| | gcn-1 | Protein CBG15647. (906 aa) |
| | daf-21 | Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] (706 aa) |
