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CBG12840 CBG12840 puf-5 puf-5 nmy-1 nmy-1 dbt-1 dbt-1 xpf-1 xpf-1 tsp-12 tsp-12 hmg-3 hmg-3 vbh-1 vbh-1 epg-8 epg-8 cutl-20 cutl-20 imp-2 imp-2 cutl-1 cutl-1 nmy-2 nmy-2 wrm-1 wrm-1 hmg-4 hmg-4 laf-1 laf-1 pdi-3 pdi-3 sem-2 sem-2 sig-7 sig-7 cdk-11.1 cdk-11.1 ubh-4 ubh-4 tsp-14 tsp-14 cdk-11.2 cdk-11.2 CBG17236 CBG17236 pac-1 pac-1 oma-2 oma-2 uggt-2 uggt-2 src-1 src-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG12840Protein CBG12840. (273 aa)
puf-5Protein CBR-PUF-5. (453 aa)
nmy-1Protein CBR-NMY-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
dbt-1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
xpf-1Protein CBG03141. (927 aa)
tsp-12Tetraspanin. (308 aa)
hmg-3FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (689 aa)
vbh-1Protein CBR-VBH-1; Belongs to the DEAD box helicase family. (692 aa)
epg-8Protein CBR-EPG-8. (431 aa)
cutl-20Protein CBG05129. (310 aa)
imp-2Protein CBR-IMP-2. (465 aa)
cutl-1Protein CBG06722. (365 aa)
nmy-2Protein CBR-NMY-2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2051 aa)
wrm-1Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa)
hmg-4FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (695 aa)
laf-1Protein CBR-LAF-1; Belongs to the DEAD box helicase family. (653 aa)
pdi-3Protein disulfide-isomerase. (488 aa)
sem-2Protein CBR-SEM-2. (401 aa)
sig-7Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (434 aa)
cdk-11.1Protein CBG12984. (711 aa)
ubh-4Ubiquitin carboxyl-terminal hydrolase. (326 aa)
tsp-14Tetraspanin. (440 aa)
cdk-11.2Protein CBG17235. (680 aa)
CBG17236Protein CBG17236. (304 aa)
pac-1Protein CBG18119. (1623 aa)
oma-2Protein CBR-OMA-2. (379 aa)
uggt-2Protein CBG22023. (1280 aa)
src-1Tyrosine-protein kinase. (544 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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