STRINGSTRING
age-1 age-1 CBG24914 CBG24914 CBG03566 CBG03566 plc-4 plc-4 egl-8 egl-8 piki-1 piki-1 pifk-1 pifk-1 daf-18 daf-18 pll-1 pll-1 CBG15798 CBG15798 CBG17582 CBG17582 CBG17584 CBG17584 Cbr-frm-9 Cbr-frm-9 plc-1 plc-1 plc-2 plc-2 vps-34 vps-34
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
age-1Phosphatidylinositol 3-kinase age-1; Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the [...] (1159 aa)
CBG24914Protein CBG24914. (195 aa)
CBG03566Protein CBG03566; Belongs to the PI3/PI4-kinase family. (2096 aa)
plc-4Phosphoinositide phospholipase C. (752 aa)
egl-8Phosphoinositide phospholipase C. (1528 aa)
piki-1Protein CBR-PIKI-1; Belongs to the PI3/PI4-kinase family. (1680 aa)
pifk-1Protein CBG08090; Belongs to the PI3/PI4-kinase family. (682 aa)
daf-18Protein CBR-DAF-18. (992 aa)
pll-1Phosphoinositide phospholipase C. (1083 aa)
CBG15798Protein CBG15798. (197 aa)
CBG17582Protein CBG17582. (396 aa)
CBG17584Protein CBG17584. (1313 aa)
Cbr-frm-9Protein CBR-FRM-9. (455 aa)
plc-1Phosphoinositide phospholipase C. (1917 aa)
plc-2Phosphoinositide phospholipase C. (933 aa)
vps-34Phosphatidylinositol 3-kinase catalytic subunit type 3. (895 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (28%) [HD]