(51 nodes) Regulation of mRNA splicing, via spliceosome network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gld-1	Protein CBR-GLD-1. (467 aa)
	sfa-1	Protein CBR-SFA-1. (664 aa)
	exc-7	Protein CBR-EXC-7. (676 aa)
	grld-1	Protein CBR-GRLD-1. (516 aa)
	CBG01584	Protein CBG01584. (835 aa)
	CBG01583	Protein CBG01583. (176 aa)
	fox-1	Protein CBR-FOX-1. (433 aa)
	rsp-1	Protein CBR-RSP-1. (304 aa)
	rsp-4	Protein CBR-RSP-4. (125 aa)
	Cbr-rnp-8.2	Protein CBR-RNP-8.2. (644 aa)
	nova-1	Protein CBG05583. (404 aa)
	CBG06045	Protein CBG06045. (289 aa)
	CBG07137	Protein CBG07137. (272 aa)
	etr-1	Protein CBR-ETR-1. (643 aa)
	smu-1	Protein CBR-SMU-1. (510 aa)
	rsr-1	Protein CBR-RSR-1. (581 aa)
	CBG08345	Protein CBG08345. (208 aa)
	fubl-1	Protein CBG09562. (568 aa)
	CBG10243	Protein CBG10243. (387 aa)
	CBG10565	Protein CBG10565. (453 aa)
	CBG12024	Protein CBG12024. (806 aa)
	mfap-1	Protein CBR-MFAP-1. (467 aa)
	hrpk-1	Protein CBG12588. (398 aa)
	asd-2	Protein CBR-ASD-2. (397 aa)
	CBG12765	Protein CBG12765. (713 aa)
	CBG13298	Protein CBG13298. (178 aa)
	rsp-8	Protein CBR-RSP-8. (298 aa)
	CBG13679	Protein CBG13679. (380 aa)
	CBG13807	Protein CBG13807. (414 aa)
	sup-12	Protein CBR-SUP-12. (252 aa)
	rnp-6	Protein CBR-RNP-6. (791 aa)
	unc-75	Protein CBR-UNC-75. (515 aa)
	CBG15687	Protein CBG15687. (321 aa)
	rbm-7	Protein CBG15757. (296 aa)
	mbl-1	Muscleblind-like protein; Binds to RNA with repeat sequences CUG and CCUG. Belongs to the muscleblind family. (299 aa)
	fubl-3	Protein CBG15931. (816 aa)
	CBG16603	Protein CBG16603. (240 aa)
	sex-1	Protein CBR-SEX-1. (549 aa)
	smu-2	Protein CBR-SMU-2. (530 aa)
	spn-4	Protein CBR-SPN-4. (360 aa)
	CBG19535	Protein CBG19535. (464 aa)
	CBG19536	Protein CBG19536. (384 aa)
	asd-1	Protein CBR-ASD-1. (393 aa)
	ccdc-55	Nuclear speckle splicing regulatory protein 1 homolog; Belongs to the NSRP1 family. (393 aa)
	CBG21522	Protein CBG21522. (408 aa)
	rnp-8	Protein CBR-RNP-8.1. (617 aa)
	rbm-25	Protein CBG23510. (703 aa)
	CBG26224	Protein CBG26224. (230 aa)
	CBG25779	Protein CBG25779. (821 aa)
	CBG16520	Protein CBG16520. (620 aa)
	rpl-12	60S ribosomal protein L12; Binds directly to 26S ribosomal RNA. (165 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG01583	CBG12765	A8WRB5	A8XGI8	Protein CBG01583.	Protein CBG12765.	0.664
CBG01583	fubl-3	A8WRB5	A8XNG2	Protein CBG01583.	Protein CBG15931.	0.713
CBG01583	hrpk-1	A8WRB5	A8XG41	Protein CBG01583.	Protein CBG12588.	0.424
CBG01584	CBG13298	A8WRB4	A8XHI3	Protein CBG01584.	Protein CBG13298.	0.433
CBG01584	hrpk-1	A8WRB4	A8XG41	Protein CBG01584.	Protein CBG12588.	0.769
CBG01584	rsp-8	A8WRB4	A8XHI4	Protein CBG01584.	Protein CBR-RSP-8.	0.433
CBG06045	CBG16520	A8X113	E3CU55	Protein CBG06045.	Protein CBG16520.	0.459
CBG06045	CBG26224	A8X113	B6IEN2	Protein CBG06045.	Protein CBG26224.	0.459
CBG06045	fubl-1	A8X113	A8X8T3	Protein CBG06045.	Protein CBG09562.	0.459
CBG06045	fubl-3	A8X113	A8XNG2	Protein CBG06045.	Protein CBG15931.	0.715
CBG06045	hrpk-1	A8X113	A8XG41	Protein CBG06045.	Protein CBG12588.	0.417
CBG07137	exc-7	A8X3M4	A8WP94	Protein CBG07137.	Protein CBR-EXC-7.	0.550
CBG07137	grld-1	A8X3M4	A8WR62	Protein CBG07137.	Protein CBR-GRLD-1.	0.529
CBG07137	unc-75	A8X3M4	A8XM12	Protein CBG07137.	Protein CBR-UNC-75.	0.487
CBG08345	sup-12	A8X6C7	A8XJQ8	Protein CBG08345.	Protein CBR-SUP-12.	0.534
CBG10243	CBG13298	A8XAS1	A8XHI3	Protein CBG10243.	Protein CBG13298.	0.658
CBG10243	hrpk-1	A8XAS1	A8XG41	Protein CBG10243.	Protein CBG12588.	0.701
CBG10243	mfap-1	A8XAS1	A8XFW6	Protein CBG10243.	Protein CBR-MFAP-1.	0.418
CBG10243	rbm-25	A8XAS1	A8Y3R3	Protein CBG10243.	Protein CBG23510.	0.442
CBG10243	rnp-6	A8XAS1	A8XL16	Protein CBG10243.	Protein CBR-RNP-6.	0.404