STRINGSTRING
gras-1 gras-1 Cbr-ppw-2 Cbr-ppw-2 srf-3 srf-3 CBG24491 CBG24491 CBG24571 CBG24571 sut-2 sut-2 unc-69 unc-69 nos-2 nos-2 CBG24774 CBG24774 CBG25098 CBG25098 odr-7 odr-7 znfx-1 znfx-1 CBG01440 CBG01440 pid-5 pid-5 ced-3 ced-3 dcap-2 dcap-2 rsd-2 rsd-2 CBG01667 CBG01667 cup-2 cup-2 dyrb-1 dyrb-1 ooc-5 ooc-5 cdc-48.1 cdc-48.1 Cbr-hpo-40 Cbr-hpo-40 ubxn-1 ubxn-1 tyr-4 tyr-4 mut-16 mut-16 pid-2 pid-2 tyr-6 tyr-6 enpl-1 enpl-1 rde-8 rde-8 ife-3 ife-3 pde-2 pde-2 pdhk-2 pdhk-2 ubxn-3 ubxn-3 cat-2 cat-2 CBG07786 CBG07786 egrh-1 egrh-1 cytb-5.1 cytb-5.1 dgk-1 dgk-1 sel-12 sel-12 rund-1 rund-1 sedl-1 sedl-1 haf-6 haf-6 syx-4 syx-4 erh-1 erh-1 cni-1 cni-1 CBG09416 CBG09416 mut-14 mut-14 gly-14 gly-14 cyld-1 cyld-1 vps-53 vps-53 cnx-1 cnx-1 CBG10002 CBG10002 unc-16 unc-16 mut-7 mut-7 CBG10060 CBG10060 CBG10440 CBG10440 osm-3 osm-3 rde-12 rde-12 Cbr-tag-65 Cbr-tag-65 unc-76 unc-76 mut-15 mut-15 Cbr-cccp-1 Cbr-cccp-1 unc-108 unc-108 hop-1 hop-1 anc-1 anc-1 CBG12189 CBG12189 ran-2 ran-2 gld-4 gld-4 spe-11 spe-11 mut-2 mut-2 lbp-5 lbp-5 cdc-42 cdc-42 pde-4 pde-4 pid-1 pid-1 gld-3 gld-3 obr-1 obr-1 CBG13513 CBG13513 pkd-2 pkd-2 ubxn-2 ubxn-2 egrh-3 egrh-3 CBG14206 CBG14206 tsp-17 tsp-17 sft-4 sft-4 daf-9 daf-9 pid-3 pid-3 cav-1 cav-1 osm-9 osm-9 CBG15303 CBG15303 CBG15628 CBG15628 toca-1 toca-1 gly-13 gly-13 henn-1 henn-1 mob-4 mob-4 ogt-1 ogt-1 gly-12 gly-12 vps-52 vps-52 CBG17314 CBG17314 ntp-1 ntp-1 tyr-2 tyr-2 tost-1 tost-1 erh-2 erh-2 glr-1 glr-1 rme-1 rme-1 CBG19180 CBG19180 spas-1 spas-1 CBG19371 CBG19371 amph-1 amph-1 CBG20160 CBG20160 pid-4 pid-4 CBG20872 CBG20872 nos-1 nos-1 cua-1 cua-1 tor-2 tor-2 CBG21319 CBG21319 cid-1 cid-1 CBG21499 CBG21499 tyr-3 tyr-3 rde-2 rde-2 spe-4 spe-4 CBG23936 CBG23936 CBG26117 CBG26117 sir-2.1 sir-2.1 CBG23170 CBG23170 ced-4 ced-4 rsef-1 rsef-1 odr-8 odr-8 daf-21 daf-21 tofu-6 tofu-6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gras-1Protein CBG23728. (245 aa)
Cbr-ppw-2Protein CBR-PPW-2; Belongs to the argonaute family. (993 aa)
srf-3Protein CBR-SRF-3. (345 aa)
CBG24491Protein CBG24491. (402 aa)
CBG24571Protein CBG24571. (223 aa)
sut-2Protein CBR-SUT-2. (722 aa)
unc-69Protein CBR-UNC-69. (108 aa)
nos-2Protein CBR-NOS-2; Belongs to the nanos family. (262 aa)
CBG24774Protein CBG24774. (120 aa)
CBG25098Protein CBG25098. (203 aa)
odr-7Protein CBR-ODR-7. (446 aa)
znfx-1Protein CBG00906. (2047 aa)
CBG01440Protein CBG01440; Belongs to the peptidase M24B family. (942 aa)
pid-5Protein CBG01441. (137 aa)
ced-3Protein CBR-CED-3; Belongs to the peptidase C14A family. (508 aa)
dcap-2Protein CBR-DCAP-2. (762 aa)
rsd-2Protein CBR-RSD-2. (1197 aa)
CBG01667Protein CBG01667. (823 aa)
cup-2Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (245 aa)
dyrb-1Dynein light chain roadblock. (95 aa)
ooc-5Torsin. (346 aa)
cdc-48.1Protein CBG03070; Belongs to the AAA ATPase family. (865 aa)
Cbr-hpo-40Protein CBR-HPO-40. (608 aa)
ubxn-1Protein CBR-UBXN-1. (305 aa)
tyr-4Protein CBR-TYR-4. (775 aa)
mut-16Protein CBR-MUT-16. (1038 aa)
pid-2Protein CBG04282. (587 aa)
tyr-6Protein CBR-TYR-6. (761 aa)
enpl-1Protein CBG06014. (776 aa)
rde-8Protein CBG05767. (341 aa)
ife-3Protein CBR-IFE-3; Belongs to the eukaryotic initiation factor 4E family. (242 aa)
pde-2Phosphodiesterase. (959 aa)
pdhk-2Protein-serine/threonine kinase. (486 aa)
ubxn-3Protein CBR-UBXN-3. (592 aa)
cat-2Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior (By similarity). Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. (517 aa)
CBG07786Protein CBG07786. (174 aa)
egrh-1Protein CBR-EGRH-1. (480 aa)
cytb-5.1Protein CBR-CYTB-5.1; Belongs to the cytochrome b5 family. (134 aa)
dgk-1Diacylglycerol kinase. (953 aa)
sel-12Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
rund-1Protein CBG08133. (564 aa)
sedl-1Protein CBR-SEDL-1. (141 aa)
haf-6Protein CBR-HAF-6. (605 aa)
syx-4Protein CBR-SYX-4; Belongs to the syntaxin family. (293 aa)
erh-1Enhancer of rudimentary homolog; May have a role in the cell cycle. (103 aa)
cni-1Protein CBR-CNIH-2. (145 aa)
CBG09416Protein CBG09416; Belongs to the argonaute family. (939 aa)
mut-14Protein CBR-MUT-14; Belongs to the DEAD box helicase family. (527 aa)
gly-14Protein CBR-GLY-14. (441 aa)
cyld-1Protein CBR-CYLD-1. (1175 aa)
vps-53Protein CBG09978. (796 aa)
cnx-1Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death (By similarity). (623 aa)
CBG10002Protein CBG10002. (768 aa)
unc-16Protein CBR-UNC-16. (1158 aa)
mut-7Protein CBR-MUT-7. (927 aa)
CBG10060Protein CBG10060. (816 aa)
CBG10440Protein CBG10440; Belongs to the cytochrome P450 family. (556 aa)
osm-3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (706 aa)
rde-12Protein CBG11510. (1248 aa)
Cbr-tag-65Protein CBR-TAG-65. (667 aa)
unc-76Protein CBR-UNC-76. (232 aa)
mut-15Protein CBR-MUT-15. (689 aa)
Cbr-cccp-1Protein CBR-CCCP-1. (1065 aa)
unc-108Protein CBR-UNC-108. (214 aa)
hop-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
anc-1Protein CBR-ANC-1. (3414 aa)
CBG12189Protein CBG12189. (215 aa)
ran-2Protein CBR-RAN-2. (975 aa)
gld-4Protein CBR-GLD-4. (893 aa)
spe-11Protein CBR-SPE-11. (289 aa)
mut-2Protein CBR-MUT-2. (446 aa)
lbp-5Protein CBR-LBP-5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (136 aa)
cdc-42Protein CBR-CDC-42. (191 aa)
pde-4Phosphodiesterase. (785 aa)
pid-1Protein CBG13034. (167 aa)
gld-3Protein CBR-GLD-3. (956 aa)
obr-1Oxysterol-binding protein; Belongs to the OSBP family. (762 aa)
CBG13513Protein CBG13513. (505 aa)
pkd-2Protein CBR-PKD-2. (716 aa)
ubxn-2Protein CBR-UBXN-2. (702 aa)
egrh-3Protein CBR-EGRH-3. (299 aa)
CBG14206Protein CBG14206. (297 aa)
tsp-17Tetraspanin. (277 aa)
sft-4Protein CBR-SFT-4. (277 aa)
daf-9Protein CBR-DAF-9; Belongs to the cytochrome P450 family. (614 aa)
pid-3Protein CBG14989. (304 aa)
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
osm-9Protein CBR-OSM-9; Belongs to the transient receptor (TC 1.A.4) family. (940 aa)
CBG15303Protein CBG15303. (494 aa)
CBG15628Protein CBG15628. (121 aa)
toca-1Protein CBR-TOCA-1. (588 aa)
gly-13Protein CBR-GLY-13. (450 aa)
henn-1Protein CBG16658. (445 aa)
mob-4Protein CBG16661. (223 aa)
ogt-1Protein CBR-OGT-1. (1184 aa)
gly-12Protein CBR-GLY-12. (467 aa)
vps-52Protein CBR-VPS-52. (702 aa)
CBG17314Protein CBG17314. (1151 aa)
ntp-1Protein CBR-NTP-1; Belongs to the GDA1/CD39 NTPase family. (511 aa)
tyr-2Protein CBR-TYR-2. (679 aa)
tost-1Protein CBG17949. (137 aa)
erh-2Protein CBG18033. (111 aa)
glr-1Protein CBR-GLR-1. (978 aa)
rme-1Protein CBR-RME-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (611 aa)
CBG19180Protein CBG19180. (387 aa)
spas-1Probable spastin homolog spas-1; Severs microtubules, probably in an ATP-dependent fashion. Belongs to the AAA ATPase family. Spastin subfamily. (542 aa)
CBG19371Protein CBG19371. (462 aa)
amph-1Protein CBR-AMPH-1. (482 aa)
CBG20160Protein CBG20160. (174 aa)
pid-4Protein CBG20484. (673 aa)
CBG20872Protein CBG20872. (125 aa)
nos-1Protein CBR-NOS-1; Belongs to the nanos family. (246 aa)
cua-1Protein CBR-CUA-1. (1271 aa)
tor-2Protein CBG21284. (343 aa)
CBG21319Protein CBG21319. (137 aa)
cid-1Protein CBR-CID-1. (1070 aa)
CBG21499Protein CBG21499. (446 aa)
tyr-3Protein CBR-TYR-3. (693 aa)
rde-2Protein CBR-RDE-2. (709 aa)
spe-4Protein CBR-SPE-4. (483 aa)
CBG23936Protein CBG23936. (1003 aa)
CBG26117Protein CBG26117. (82 aa)
sir-2.1NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase. Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased life-span. May also regulate life-span independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticulum (ER). Acts upstream of the nicotinic acid metabolism pathway, which may be linked to the r [...] (602 aa)
CBG23170Probable RING finger protein 207 homolog. (836 aa)
ced-4Cell death protein 4; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to induce caspase ced-3 autoproteolytic cleavage and activation. Also forms an holoenzyme with processed ced-3 enhancing ced-3 activity. Component of the egl-1, ced-9, ced-4 and ced- 3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During [...] (569 aa)
rsef-1Ras and EF-hand domain-containing protein homolog; Binds GTP and GDP. Plays a role in uterine seam cell development. (634 aa)
odr-8Ufm1-specific protease; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins. Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels. (588 aa)
daf-21Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] (706 aa)
tofu-6Embryonic developmental protein tofu-6; Required maternally for early embryonic cell divisions. May have a role in DNA replication. (365 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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