STRINGSTRING
mab-9.2 mab-9.2 umps-1 umps-1 nas-6 nas-6 mig-5 mig-5 pyr-1 pyr-1 sup-37 sup-37 abu-14 abu-14 ubc-9 ubc-9 CBG01565 CBG01565 wsp-1 wsp-1 vang-1 vang-1 CBG02722 CBG02722 dsh-2 dsh-2 gex-3 gex-3 lim-7 lim-7 lin-35 lin-35 hmg-3 hmg-3 pop-1 pop-1 sys-1 sys-1 mom-5 mom-5 nas-5 nas-5 hda-1 hda-1 ceh-28 ceh-28 CBG05231 CBG05231 CBG05575 CBG05575 pha-4 pha-4 let-653 let-653 rib-1 rib-1 CBG06569 CBG06569 hlh-6 hlh-6 glp-1 glp-1 sma-2 sma-2 mab-9.1 mab-9.1 pha-2 pha-2 Cbr-abu-8 Cbr-abu-8 CBG08691 CBG08691 Cbr-abu-7 Cbr-abu-7 Cbr-abu-6 Cbr-abu-6 let-413 let-413 src-2 src-2 CBG09063 CBG09063 wrm-1 wrm-1 hmg-4 hmg-4 lin-48 lin-48 ceh-22 ceh-22 CBG10973 CBG10973 CBG10974 CBG10974 unc-52 unc-52 mom-2 mom-2 hil-1 hil-1 CBG11789 CBG11789 lin-59 lin-59 tnt-4 tnt-4 nas-7 nas-7 rsa-2 rsa-2 pen-2 pen-2 eps-8 eps-8 peb-1 peb-1 CBG15416 CBG15416 toca-1 toca-1 ubc-18 ubc-18 lin-37 lin-37 CBG16516 CBG16516 sma-3 sma-3 ten-1 ten-1 apy-1 apy-1 CBG16744 CBG16744 egl-15 egl-15 toca-2 toca-2 rib-2 rib-2 sqv-1 sqv-1 efl-1 efl-1 wve-1 wve-1 mig-14 mig-14 tbx-2 tbx-2 aph-2 aph-2 src-1 src-1 sup-36 sup-36 lin-36 lin-36 sma-1 sma-1 aph-1 aph-1 CBG25505 CBG25505 CBG23879 CBG23879 CBG23773 CBG23773 sqv-8 sqv-8 lin-53 lin-53
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mab-9.2Protein CBR-MAB-9.2. (342 aa)
umps-1Protein CBR-UMPS-1. (498 aa)
nas-6Metalloendopeptidase. (341 aa)
mig-5Protein CBR-MIG-5. (657 aa)
pyr-1Protein CBR-PYR-1. (2090 aa)
sup-37Protein CBG00762. (987 aa)
abu-14Protein CBR-ABU-14. (383 aa)
ubc-9Protein CBR-UBC-9; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
CBG01565Protein CBG01565. (188 aa)
wsp-1Protein CBR-WSP-1. (785 aa)
vang-1Vang-like protein. (532 aa)
CBG02722Protein CBG02722. (311 aa)
dsh-2Protein CBR-DSH-2. (784 aa)
gex-3Protein CBR-GEX-3. (1140 aa)
lim-7Protein CBR-LIM-7. (458 aa)
lin-35Protein CBR-LIN-35. (956 aa)
hmg-3FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (689 aa)
pop-1Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage- derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. Belongs t [...] (439 aa)
sys-1Protein CBR-SYS-1. (839 aa)
mom-5Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
nas-5Metalloendopeptidase. (372 aa)
hda-1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
ceh-28Protein CBR-CEH-28. (100 aa)
CBG05231Protein CBG05231; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
CBG05575Protein CBG05575. (166 aa)
pha-4Protein CBR-PHA-4. (477 aa)
let-653Protein CBR-LET-653. (736 aa)
rib-1Protein CBR-RIB-1; Belongs to the glycosyltransferase 47 family. (343 aa)
CBG06569Protein CBG06569. (347 aa)
hlh-6Protein CBR-HLH-6. (144 aa)
glp-1Protein CBR-GLP-1. (1326 aa)
sma-2Dwarfin sma. (399 aa)
mab-9.1Protein CBR-MAB-9.1. (331 aa)
pha-2Protein CBR-PHA-2. (211 aa)
Cbr-abu-8Protein CBR-ABU-8. (443 aa)
CBG08691Protein CBG08691. (326 aa)
Cbr-abu-7Protein CBR-ABU-7. (432 aa)
Cbr-abu-6Protein CBR-ABU-6. (383 aa)
let-413Protein CBR-LET-413. (702 aa)
src-2Tyrosine-protein kinase. (512 aa)
CBG09063Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
wrm-1Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa)
hmg-4FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (695 aa)
lin-48Protein CBR-LIN-48. (290 aa)
ceh-22Protein CBR-CEH-22. (356 aa)
CBG10973Protein CBG10973. (372 aa)
CBG10974Protein CBG10974. (318 aa)
unc-52Protein CBR-UNC-52. (2481 aa)
mom-2Protein CBR-MOM-2. (358 aa)
hil-1Protein CBR-HIL-1. (233 aa)
CBG11789Protein CBG11789. (244 aa)
lin-59Protein CBR-LIN-59. (1320 aa)
tnt-4Protein CBR-TNT-4. (308 aa)
nas-7Metalloendopeptidase. (389 aa)
rsa-2Protein CBR-RSA-2. (1045 aa)
pen-2Protein CBR-PEN-2. (101 aa)
eps-8Protein CBR-EPS-8. (918 aa)
peb-1Protein CBR-PEB-1. (432 aa)
CBG15416Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (470 aa)
toca-1Protein CBR-TOCA-1. (588 aa)
ubc-18Protein CBR-UBC-18. (153 aa)
lin-37Protein CBR-LIN-37. (274 aa)
CBG16516Protein CBG16516. (225 aa)
sma-3Dwarfin sma. (365 aa)
ten-1Protein CBR-TEN-1. (2909 aa)
apy-1Protein CBG16731. (354 aa)
CBG16744Protein CBG16744. (663 aa)
egl-15Receptor protein-tyrosine kinase. (1192 aa)
toca-2Protein CBR-TOCA-2. (677 aa)
rib-2Protein CBR-RIB-2; Belongs to the glycosyltransferase 47 family. (877 aa)
sqv-1Protein CBR-SQV-1. (456 aa)
efl-1Protein CBR-EFL-1. (303 aa)
wve-1Protein CBR-WVE-1. (475 aa)
mig-14Protein CBR-MIG-14. (548 aa)
tbx-2Protein CBR-TBX-2. (426 aa)
aph-2Protein CBR-APH-2. (721 aa)
src-1Tyrosine-protein kinase. (544 aa)
sup-36Protein CBG23027. (169 aa)
lin-36Protein CBR-LIN-36. (1111 aa)
sma-1Protein CBR-SMA-1. (4156 aa)
aph-1Protein CBR-APH-1. (330 aa)
CBG25505Protein CBG25505. (207 aa)
CBG23879Protein CBG23879. (272 aa)
CBG23773Protein CBG23773. (514 aa)
sqv-8Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (356 aa)
lin-53Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. (416 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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