STRINGSTRING
ceh-18 ceh-18 ego-1 ego-1 tut-1 tut-1 atz-1 atz-1 sir-2.4 sir-2.4 rsd-6 rsd-6 rme-2 rme-2 lag-1 lag-1 cyb-3 cyb-3 CBG05915 CBG05915 lip-1 lip-1 glp-1 glp-1 drh-3 drh-3 npp-10 npp-10 acy-4 acy-4 elpc-1 elpc-1 inx-14 inx-14 inx-22 inx-22 Cbr-tag-250 Cbr-tag-250 vab-1 vab-1 mek-1 mek-1 eri-5 eri-5 csr-1 csr-1 cyb-1 cyb-1 atx-2 atx-2 CBG20325 CBG20325 ekl-1 ekl-1 rab-7 rab-7 mpk-1 mpk-1 oma-2 oma-2 gsa-1 gsa-1 pptr-1 pptr-1 pptr-2 pptr-2 aph-1 aph-1 CBG26743 CBG26743 emo-1 emo-1 itr-1 itr-1 elpc-3 elpc-3 arf-1.2 arf-1.2 mep-1 mep-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ceh-18POU domain protein. (545 aa)
ego-1Protein CBR-EGO-1. (1631 aa)
tut-1Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (372 aa)
atz-1Protein CBG03320. (369 aa)
sir-2.4Protein CBR-SIR-2.4. (324 aa)
rsd-6Protein CBR-RSD-6. (813 aa)
rme-2Protein CBR-RME-2. (929 aa)
lag-1Protein CBR-LAG-1. (681 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
CBG05915Protein CBG05915. (546 aa)
lip-1Protein CBR-LIP-1. (376 aa)
glp-1Protein CBR-GLP-1. (1326 aa)
drh-3Protein CBR-DRH-3. (846 aa)
npp-10Protein CBR-NPP-10. (1684 aa)
acy-4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1000 aa)
elpc-1Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1214 aa)
inx-14Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (563 aa)
inx-22Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (454 aa)
Cbr-tag-250Protein CBR-TAG-250. (620 aa)
vab-1Protein CBR-VAB-1. (1118 aa)
mek-1Protein CBR-MEK-1. (463 aa)
eri-5Protein CBR-ERI-5. (564 aa)
csr-1Protein CBR-CSR-1. (1003 aa)
cyb-1Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa)
atx-2Protein CBR-ATX-2. (1051 aa)
CBG20325Protein CBG20325. (303 aa)
ekl-1Protein CBR-EKL-1. (644 aa)
rab-7Protein CBR-RAB-7. (209 aa)
mpk-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
oma-2Protein CBR-OMA-2. (379 aa)
gsa-1Protein CBR-GSA-1. (326 aa)
pptr-1Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (531 aa)
pptr-2Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (556 aa)
aph-1Protein CBR-APH-1. (330 aa)
CBG26743Protein CBG26743. (197 aa)
emo-1Protein CBR-EMO-1. (68 aa)
itr-1Protein CBR-ITR-1, isoform a. (2921 aa)
elpc-3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5- carbamoylmethyl uridine) (By similarity). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at po [...] (548 aa)
arf-1.2ADP-ribosylation factor 1-like 2; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Involved in endoplasmic reticulum dynamics during embryogenesis. Also required for adult germline function (By similarity); Belongs to the small GTPase superfamily. Arf family. (181 aa)
mep-1MOG interacting and ectopic P-granules protein 1; Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate. Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch. Acts by regulating the translation of fem-3 mRNA, by binding to its 3'-UTR (By similarity). (880 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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