STRINGSTRING
asna-1 asna-1 mig-14 mig-14 flp-2 flp-2 emb-9 emb-9 aex-4 aex-4 dpy-23 dpy-23 aak-2 aak-2 pdf-1 pdf-1 frpr-18 frpr-18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
asna-1ATPase asna-1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (345 aa)
mig-14Protein CBR-MIG-14. (548 aa)
flp-2Protein CBR-FLP-2. (73 aa)
emb-9Protein CBR-EMB-9. (1759 aa)
aex-4Protein CBR-AEX-4. (209 aa)
dpy-23Protein CBR-DPY-23; Belongs to the adaptor complexes medium subunit family. (435 aa)
aak-2Non-specific serine/threonine protein kinase. (641 aa)
pdf-1Protein CBG16474. (86 aa)
frpr-18Protein CBR-FRPR-18; Belongs to the G-protein coupled receptor 1 family. (432 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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