STRINGSTRING
emre-1 emre-1 zipt-7.2 zipt-7.2 ftn-2 ftn-2 CBG12308 CBG12308 cln-3.2 cln-3.2 nhx-2 nhx-2 kcc-3 kcc-3 CBG13067 CBG13067 CBG13453 CBG13453 CBG13537 CBG13537 CBG13538 CBG13538 CBG13771 CBG13771 zipt-15 zipt-15 smf-3 smf-3 CBG14120 CBG14120 cnnm-3 cnnm-3 amt-1 amt-1 cav-1 cav-1 trp-2 trp-2 CBG15341 CBG15341 pgrn-1 pgrn-1 cnnm-2 cnnm-2 CBG15451 CBG15451 rig-1 rig-1 CBG15669 CBG15669 stim-1 stim-1 ttm-1 ttm-1 unc-68 unc-68 Cbr-nkcc-1 Cbr-nkcc-1 cutc-1 cutc-1 trp-1 trp-1 CBG19651 CBG19651 mca-1 mca-1 CBG20077 CBG20077 CBG20078 CBG20078 CBG20079 CBG20079 CBG20975 CBG20975 vha-19 vha-19 CBG21176 CBG21176 cua-1 cua-1 CBG21257 CBG21257 wnk-1 wnk-1 CBG21734 CBG21734 glrx-3 glrx-3 ccdc-47 ccdc-47 vha-7 vha-7 catp-6 catp-6 mca-3 mca-3 frh-1 frh-1 abts-3 abts-3 vha-6 vha-6 mgl-2 mgl-2 CBG01948 CBG01948 vha-5 vha-5 CBG01593 CBG01593 catp-4 catp-4 cnnm-4 cnnm-4 CBG22300 CBG22300 CBG22375 CBG22375 mca-2 mca-2 nhr-14 nhr-14 CBG23048 CBG23048 zipt-16 zipt-16 cln-3.1 cln-3.1 CBG23102 CBG23102 CBG25583 CBG25583 CBG26382 CBG26382 CBG26357 CBG26357 CBG25193 CBG25193 vha-2 vha-2 vha-3 vha-3 sco-1 sco-1 abtm-1 abtm-1 abts-1 abts-1 nkb-1 nkb-1 calm-1 calm-1 ncx-4 ncx-4 nkb-2 nkb-2 nhx-5 nhx-5 CBG04646 CBG04646 pept-1 pept-1 cdf-1 cdf-1 amt-4.1 amt-4.1 vha-12 vha-12 vha-13 vha-13 mfn-1 mfn-1 rhr-1 rhr-1 rhr-2 rhr-2 catp-5 catp-5 zipt-13 zipt-13 abts-2 abts-2 aco-1 aco-1 pbo-4 pbo-4 haly-1 haly-1 sca-1 sca-1 kcc-2 kcc-2 hif-1 hif-1 unc-80 unc-80 nhx-9 nhx-9 catp-8 catp-8 kcc-1 kcc-1 CBG06677 CBG06677 unc-32 unc-32 CBG07084 CBG07084 rab-14 rab-14 micu-1 micu-1 cox-11 cox-11 cln-3.3 cln-3.3 CBG15848 CBG15848 nhx-1 nhx-1 CBG16370 CBG16370 vha-20 vha-20 CBG16448 CBG16448 pdfr-1 pdfr-1 CBG11156 CBG11156 letm-1 letm-1 Cbr-tag-65 Cbr-tag-65 catp-3 catp-3 unc-108 unc-108 mcu-1 mcu-1 ncx-5 ncx-5 CBG09737 CBG09737 catp-1 catp-1 CBG08742 CBG08742 atp-1 atp-1 ncx-10 ncx-10 ncx-9 ncx-9 CBG08638 CBG08638 CBG08664 CBG08664 cnnm-5 cnnm-5 nhx-8 nhx-8 vha-9 vha-9 ftn-1 ftn-1 nhx-3 nhx-3 CBG00821 CBG00821 CBG00622 CBG00622 amt-3 amt-3 zipt-17 zipt-17 zipt-7.1 zipt-7.1 cnnm-1 cnnm-1 cdf-2 cdf-2 CBG24897 CBG24897 CBG24663 CBG24663 catp-7 catp-7 amt-2 amt-2 CBG23828 CBG23828 CBG09449 CBG09449 eat-6 eat-6 spe-41 spe-41 vha-1 vha-1 ncx-7 ncx-7 ncx-6 ncx-6 CBG10069 CBG10069 CBG10764 CBG10764 Cbr-vha-16 Cbr-vha-16 Cbr-tag-300 Cbr-tag-300 smf-2 smf-2 smf-1 smf-1 abts-4 abts-4 nhx-4 nhx-4 pmr-1 pmr-1 CBG07249 CBG07249 nkb-3 nkb-3 rbc-1 rbc-1 csq-1 csq-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
emre-1Protein CBR-TAG-299. (91 aa)
zipt-7.2Zinc transporter zipt-7.2; Zinc transporter; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (476 aa)
ftn-2Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (170 aa)
CBG12308Protein CBG12308. (257 aa)
cln-3.2Battenin. (445 aa)
nhx-2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (668 aa)
kcc-3Protein CBR-KCC-2. (1100 aa)
CBG13067Protein CBG13067. (625 aa)
CBG13453Protein CBG13453. (146 aa)
CBG13537Protein CBG13537. (82 aa)
CBG13538Protein CBG13538. (57 aa)
CBG13771Protein CBG13771. (126 aa)
zipt-15Protein CBG13990. (421 aa)
smf-3Protein CBR-SMF-3. (560 aa)
CBG14120Protein CBG14120. (248 aa)
cnnm-3Protein CBG14121. (417 aa)
amt-1Ammonium transporter. (534 aa)
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
trp-2Protein CBR-TRP-2; Belongs to the transient receptor (TC 1.A.4) family. (965 aa)
CBG15341Protein CBG15341. (937 aa)
pgrn-1Protein CBR-PGRN-1. (291 aa)
cnnm-2Protein CBG15463. (773 aa)
CBG15451Protein CBG15451. (183 aa)
rig-1Protein CBR-RIG-1. (1170 aa)
CBG15669GDT1 family protein. (293 aa)
stim-1Protein CBR-STIM-1. (550 aa)
ttm-1Protein CBR-TTM-1. (388 aa)
unc-68Protein CBR-LIPL-6. (6513 aa)
Cbr-nkcc-1Protein CBR-NKCC-1. (1191 aa)
cutc-1Protein CBR-CUTC-1. (250 aa)
trp-1Protein CBR-TRP-1; Belongs to the transient receptor (TC 1.A.4) family. (1055 aa)
CBG19651Protein CBG19651; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1166 aa)
mca-1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
CBG20077Protein CBG20077. (165 aa)
CBG20078Protein CBG20078. (137 aa)
CBG20079Protein CBG20079. (361 aa)
CBG20975Protein CBG20975. (270 aa)
vha-19Protein CBR-VHA-19. (453 aa)
CBG21176Protein CBG21176. (174 aa)
cua-1Protein CBR-CUA-1. (1271 aa)
CBG21257Protein CBG21257; Belongs to the BolA/IbaG family. (108 aa)
wnk-1Protein CBR-WNK-1. (1770 aa)
CBG21734Protein CBG21734. (1339 aa)
glrx-3Protein CBR-GLRX-3. (345 aa)
ccdc-47Protein CBR-CCDC-47. (455 aa)
vha-7Protein CBR-VHA-7. (1396 aa)
catp-6Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1172 aa)
mca-3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1159 aa)
frh-1Protein CBR-FRH-1. (136 aa)
abts-3Protein CBR-ABTS-3. (1016 aa)
vha-6V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (867 aa)
mgl-2Protein CBR-MGL-2. (1083 aa)
CBG01948Protein CBG01948. (249 aa)
vha-5V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (888 aa)
CBG01593Protein CBG01593; Belongs to the G-protein coupled receptor 3 family. (1395 aa)
catp-4Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
cnnm-4Protein CBG21926. (508 aa)
CBG22300Protein CBG22300. (289 aa)
CBG22375Protein CBG22375; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (153 aa)
mca-2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1165 aa)
nhr-14Protein CBR-NHR-14. (440 aa)
CBG23048Protein CBG23048. (467 aa)
zipt-16Protein CBR-TAG-140. (511 aa)
cln-3.1Battenin. (423 aa)
CBG23102V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
CBG25583Protein CBG25583. (85 aa)
CBG26382Protein CBG26382. (95 aa)
CBG26357Protein CBG26357. (148 aa)
CBG25193Protein CBG25193. (141 aa)
vha-2V-type proton ATPase 16 kDa proteolipid subunit 2; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The in [...] (161 aa)
vha-3V-type proton ATPase 16 kDa proteolipid subunit 3; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The in [...] (161 aa)
sco-1Protein CBR-SCO-1. (318 aa)
abtm-1Protein CBR-ABTM-1. (878 aa)
abts-1Anion exchange protein. (1178 aa)
nkb-1Protein CBR-NKB-1. (319 aa)
calm-1Protein CBR-CALM-1. (143 aa)
ncx-4Protein CBR-NCX-4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (604 aa)
nkb-2Protein CBR-NKB-2. (378 aa)
nhx-5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (632 aa)
CBG04646Protein CBG04646. (178 aa)
pept-1Protein CBR-PEPT-1. (838 aa)
cdf-1Protein CBR-CDF-1. (545 aa)
amt-4.1Ammonium transporter. (582 aa)
vha-12Probable V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Required for necrotic cell death and epidermal cell fusion (By similarity). Belongs to the ATPase alpha/beta chains family. (491 aa)
vha-13V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (Probable). V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (Probable). Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad (By similarity). This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization (By similarity). The in [...] (606 aa)
mfn-1Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
rhr-1Protein CBR-RHR-1; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (463 aa)
rhr-2Protein CBR-RHR-2; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (457 aa)
catp-5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1227 aa)
zipt-13Protein CBG17194. (353 aa)
abts-2Protein CBR-ABTS-2. (754 aa)
aco-1Protein CBR-ACO-1; Belongs to the aconitase/IPM isomerase family. (909 aa)
pbo-4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
haly-1Histidine ammonia-lyase; Belongs to the PAL/histidase family. (747 aa)
sca-1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1081 aa)
kcc-2Protein CBR-KCC-3. (973 aa)
hif-1Protein CBR-HIF-1. (843 aa)
unc-80Protein CBR-UNC-80. (3520 aa)
nhx-9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (666 aa)
catp-8Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1219 aa)
kcc-1Protein CBR-KCC-1. (1109 aa)
CBG06677Protein CBG06677. (456 aa)
unc-32V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (953 aa)
CBG07084Protein CBG07084. (959 aa)
rab-14Protein CBR-RAB-14. (210 aa)
micu-1Calcium uptake protein 1 homolog, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU). Belongs to the MICU1 family. MICU1 subfamily. (533 aa)
cox-11Protein CBG01804. (426 aa)
cln-3.3Battenin. (416 aa)
CBG15848Protein CBG15848. (438 aa)
nhx-1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (511 aa)
CBG16370Protein CBG16370. (284 aa)
vha-20Protein CBG16307. (329 aa)
CBG16448Protein CBG16448. (739 aa)
pdfr-1Protein CBG16586; Belongs to the G-protein coupled receptor 2 family. (549 aa)
CBG11156Protein CBG11156. (162 aa)
letm-1Protein CBR-LETM-1. (777 aa)
Cbr-tag-65Protein CBR-TAG-65. (667 aa)
catp-3Protein CBG11371; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1063 aa)
unc-108Protein CBR-UNC-108. (214 aa)
mcu-1Protein CBR-MCU-1. (333 aa)
ncx-5Protein CBR-NCX-5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (660 aa)
CBG09737Protein CBG09737. (395 aa)
catp-1Protein CBR-CATP-1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1130 aa)
CBG08742Protein CBG08742. (746 aa)
atp-1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (579 aa)
ncx-10Protein CBR-NCX-10; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (655 aa)
ncx-9Protein CBR-NCX-9; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (701 aa)
CBG08638Protein CBG08638; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (739 aa)
CBG08664Protein CBG08664. (130 aa)
cnnm-5Protein CBG08227. (745 aa)
nhx-8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (665 aa)
vha-9V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (121 aa)
ftn-1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (170 aa)
nhx-3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (686 aa)
CBG00821Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (587 aa)
CBG00622Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (186 aa)
amt-3Ammonium transporter. (704 aa)
zipt-17Protein CBR-TAG-141. (347 aa)
zipt-7.1Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels (By similarity). Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (By similarity). Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (By similarity). The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable [...] (392 aa)
cnnm-1Protein CBG00360. (801 aa)
cdf-2Protein CBR-CDF-2. (360 aa)
CBG24897Protein CBG24897. (98 aa)
CBG24663Protein CBG24663. (265 aa)
catp-7Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1111 aa)
amt-2Ammonium transporter. (507 aa)
CBG23828Protein CBG23828. (269 aa)
CBG09449Protein CBG09449. (351 aa)
eat-6Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
spe-41Protein CBR-SPE-41. (807 aa)
vha-1V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (166 aa)
ncx-7Protein CBR-NCX-7; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (687 aa)
ncx-6Protein CBR-NCX-6; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (592 aa)
CBG10069Protein CBG10069. (266 aa)
CBG10764Protein CBG10764. (266 aa)
Cbr-vha-16Protein CBR-VHA-16. (292 aa)
Cbr-tag-300Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (501 aa)
smf-2Protein CBR-SMF-2. (545 aa)
smf-1Protein CBR-SMF-1. (577 aa)
abts-4Protein CBR-ABTS-4. (1013 aa)
nhx-4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (781 aa)
pmr-1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (978 aa)
CBG07249Protein CBG07249. (460 aa)
nkb-3Probable sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Implicated in genomic response to various soil bacteria that affects fitness, lifespan and brood size (By similarity). (326 aa)
rbc-1Protein CBR-RBC-1. (3107 aa)
csq-1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (417 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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