STRINGSTRING
cdk-5 cdk-5 emb-1 emb-1 CBG21334 CBG21334 CBG21788 CBG21788 CBG21964 CBG21964 plep-1 plep-1 CBG21913 CBG21913 CBG22081 CBG22081 ppfr-1 ppfr-1 emr-1 emr-1 CBG22322 CBG22322 puf-6.4 puf-6.4 CBG22453 CBG22453 CBG22502 CBG22502 apc-2 apc-2 CBG23414 CBG23414 bir-1 bir-1 ndc-80 ndc-80 act-2 act-2 act-4 act-4 CBG26435 CBG26435 CBG26360 CBG26360 CBG27374 CBG27374 CBG27110 CBG27110 CBG25886 CBG25886 kbp-3 kbp-3 CBG25360 CBG25360 CBG25215 CBG25215 CBG26279 CBG26279 dpy-28 dpy-28 CBG22319 CBG22319 CBG27040 CBG27040 CBG23879 CBG23879 alx-1 alx-1 CBG29119 CBG29119 zwl-1 zwl-1 figl-1 figl-1 gpa-16 gpa-16 sgo-1 sgo-1 mett-10 mett-10 cls-2 cls-2 gsp-1 gsp-1 air-2 air-2 tipn-1 tipn-1 CBG03556 CBG03556 gpb-1 gpb-1 tofu-6 tofu-6 evl-20.1 evl-20.1 gsp-2 gsp-2 cyd-1 cyd-1 cdk-4 cdk-4 cye-1 cye-1 CBG23575 CBG23575 CBG23609 CBG23609 CBG23700 CBG23700 hcp-6 hcp-6 CBG23873 CBG23873 mlc-3 mlc-3 CBG24443 CBG24443 CBG24444 CBG24444 CBG24445 CBG24445 knl-1 knl-1 CBG24625 CBG24625 goa-1 goa-1 CBG24829 CBG24829 CBG24830 CBG24830 CBG00040 CBG00040 CBG00165 CBG00165 emb-27 emb-27 ran-3 ran-3 puf-5 puf-5 CBG00631 CBG00631 zyg-9 zyg-9 mop-25.2 mop-25.2 cdc-25.4 cdc-25.4 fbxa-137 fbxa-137 CBG01362 CBG01362 CBG01364 CBG01364 CBG01365 CBG01365 CBG01375 CBG01375 atg-18 atg-18 CBG01467 CBG01467 cyp-31a2 cyp-31a2 Cbr-csn-3 Cbr-csn-3 tcl-2 tcl-2 pig-1 pig-1 CBG02011 CBG02011 CBG02130 CBG02130 CBG02137 CBG02137 CBG02150 CBG02150 CBG02161 CBG02161 CBG02162 CBG02162 CBG02167 CBG02167 CBG02169 CBG02169 CBG02222 CBG02222 ska-1 ska-1 ptc-1 ptc-1 szy-20 szy-20 Cbr-rha-1 Cbr-rha-1 ebp-2 ebp-2 npp-19 npp-19 ect-2 ect-2 mix-1 mix-1 mat-2 mat-2 npp-5 npp-5 top-2 top-2 atg-16.2 atg-16.2 lin-23 lin-23 ani-2 ani-2 egl-44 egl-44 ify-1 ify-1 cdc-14.2 cdc-14.2 cdc-14.1 cdc-14.1 fzy-1 fzy-1 dsh-2 dsh-2 kca-1 kca-1 dpy-26 dpy-26 rack-1 rack-1 egl-20 egl-20 CBG03557 CBG03557 CBG03559 CBG03559 tim-1 tim-1 CBG03913 CBG03913 cpg-1 cpg-1 let-502 let-502 Cbr-rmd-6 Cbr-rmd-6 rnt-1 rnt-1 uri-1 uri-1 mei-1 mei-1 lin-17 lin-17 pop-1 pop-1 lem-3 lem-3 ensa-1 ensa-1 cdk-7 cdk-7 icp-1 icp-1 tac-1 tac-1 scc-1 scc-1 vps-33.2 vps-33.2 CBG04461 CBG04461 unc-61 unc-61 szy-2 szy-2 CBG05204 CBG05204 CBG05213 CBG05213 CBG05455 CBG05455 zen-4 zen-4 lag-1 lag-1 cyb-3 cyb-3 maph-9 maph-9 lip-1 lip-1 puf-6.3 puf-6.3 cdc-25.2 cdc-25.2 CBG06875 CBG06875 cya-1 cya-1 CBG07665 CBG07665 CBG07602 CBG07602 gfi-3 gfi-3 ztf-6 ztf-6 rei-2 rei-2 cdc-25.3 cdc-25.3 cdc-48.3 cdc-48.3 apr-1 apr-1 nmy-2 nmy-2 CBG08365 CBG08365 cpg-2.1 cpg-2.1 scc-3 scc-3 par-6 par-6 CBG08925 CBG08925 him-10 him-10 CBG09061 CBG09061 nop-1 nop-1 npp-10 npp-10 cyk-3 cyk-3 par-3 par-3 plk-1 plk-1 lig-1 lig-1 apc-10 apc-10 klc-1 klc-1 CBG09367 CBG09367 klc-2 klc-2 CBG09790 CBG09790 mlc-4 mlc-4 bub-1 bub-1 rmd-1 rmd-1 cdk-1 cdk-1 let-99 let-99 Cbr-gpr-2 Cbr-gpr-2 Cbr-tag-300 Cbr-tag-300 mat-1 mat-1 CBG10973 CBG10973 CBG10974 CBG10974 mes-2 mes-2 unc-104 unc-104 CBG11385 CBG11385 CBG11284 CBG11284 CBG11256 CBG11256 ani-1 ani-1 pph-4.1 pph-4.1 CBG11789 CBG11789 puf-6.2 puf-6.2 mau-2 mau-2 capg-1 capg-1 ptr-2 ptr-2 egg-4 egg-4 lin-44 lin-44 CBG12075 CBG12075 CBG12081 CBG12081 prg-1 prg-1 csnk-1 csnk-1 cdc-6 cdc-6 tyr-1.2 tyr-1.2 tyr-1.1 tyr-1.1 ran-2 ran-2 kle-2 kle-2 CBG12411 CBG12411 cdc-26 cdc-26 cdc-5l cdc-5l mat-3 mat-3 knl-2 knl-2 cdc-25.1 cdc-25.1 spg-20 spg-20 mei-2 mei-2 cdc-42 cdc-42 gld-3 gld-3 CBG13129 CBG13129 insc-1 insc-1 puf-6.1 puf-6.1 smc-3 smc-3 CBG13261 CBG13261 such-1 such-1 ham-1 ham-1 CBG13581 CBG13581 rho-1 rho-1 CBG13699 CBG13699 lem-4 lem-4 jtr-1 jtr-1 mdf-2 mdf-2 mltn-13 mltn-13 CBG14574 CBG14574 egl-13 egl-13 cdk-2 cdk-2 pid-3 pid-3 CBG15077 CBG15077 CBG15203 CBG15203 par-2 par-2 cks-1 cks-1 CBG15976 CBG15976 CBG16219 CBG16219 rod-1 rod-1 CBG16744 CBG16744 efhc-1 efhc-1 czw-1 czw-1 CBG17703 CBG17703 mlc-5 mlc-5 cyk-4 cyk-4 strd-1 strd-1 cul-2 cul-2 ran-1 ran-1 cnt-2 cnt-2 CBG18353 CBG18353 atx-2 atx-2 tost-1 tost-1 mel-28 mel-28 apc-11 apc-11 erh-2 erh-2 smc-4 smc-4 cyy-1 cyy-1 unc-116 unc-116 CBG18556 CBG18556 CBG18766 CBG18766 egl-46 egl-46 spdl-1 spdl-1 rbx-1 rbx-1 CBG19457 CBG19457 dlc-1 dlc-1 unc-59 unc-59 bec-1 bec-1 cpg-2 cpg-2 rei-1 rei-1 pelo-1 pelo-1 cam-1 cam-1 CBG20268 CBG20268 CBG20238 CBG20238 cyp-42a1 cyp-42a1 CBG20324 CBG20324 CBG20333 CBG20333 sptf-3 sptf-3 him-1 him-1 CBG20515 CBG20515 egg-3 egg-3 Cbr-tag-10 Cbr-tag-10 csc-1 csc-1 bub-3 bub-3 CBG20697 CBG20697 spat-1 spat-1 lis-1 lis-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdk-5Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa)
emb-1Protein CBR-EMB-1. (82 aa)
CBG21334Protein CBG21334. (102 aa)
CBG21788Protein CBG21788. (870 aa)
CBG21964Protein CBG21964. (465 aa)
plep-1Protein CBG21963. (508 aa)
CBG21913Protein CBG21913. (618 aa)
CBG22081Protein CBG22081. (146 aa)
ppfr-1Protein CBR-PPFR-1. (1472 aa)
emr-1Protein CBR-EMR-1. (190 aa)
CBG22322Protein CBG22322. (372 aa)
puf-6.4Protein CBG22348. (395 aa)
CBG22453Protein CBG22453. (463 aa)
CBG22502Protein CBG22502. (675 aa)
apc-2Protein CBR-APC-2; Belongs to the cullin family. (700 aa)
CBG23414Protein CBG23414. (1631 aa)
bir-1Protein CBR-BIR-1. (158 aa)
ndc-80Protein CBR-NDC-80. (599 aa)
act-2Protein CBR-ACT-2. (376 aa)
act-4Protein CBG23090. (376 aa)
CBG26435Protein CBG26435. (290 aa)
CBG26360Protein CBG26360. (119 aa)
CBG27374Protein CBG27374. (172 aa)
CBG27110Protein CBG27110. (104 aa)
CBG25886Protein CBG25886. (111 aa)
kbp-3Protein CBG26140. (140 aa)
CBG25360Protein CBG25360. (135 aa)
CBG25215Protein CBG25215. (112 aa)
CBG26279Protein CBG26279. (303 aa)
dpy-28Protein CBG25999. (1510 aa)
CBG22319Protein CBG22319. (306 aa)
CBG27040Protein CBG27040. (268 aa)
CBG23879Protein CBG23879. (272 aa)
alx-1Protein CBR-ALX-1, isoform a. (893 aa)
CBG29119Protein CBG29119. (274 aa)
zwl-1Protein zwilch homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of [...] (639 aa)
figl-1Fidgetin-like protein 1; Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility (By similarity). (591 aa)
gpa-16Guanine nucleotide-binding protein alpha-16 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle; Belongs to the G-alpha family. (354 aa)
sgo-1Shugoshin; Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms; Belongs to the shugoshin family. (306 aa)
mett-10U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Involved in mRNA splicing. Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (481 aa)
cls-2Protein CLASP-2; Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming (By similarity). (791 aa)
gsp-1Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation (By similarity); Belongs to the PPP phosphatase family. PP-1 subfamily. (329 aa)
air-2Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 and zen-4 (By similarity). (302 aa)
tipn-1Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. Belongs to the CSM3 family. (239 aa)
CBG03556Leishmanolysin-like peptidase; Metalloprotease. (663 aa)
gpb-1Guanine nucleotide-binding protein subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces. (340 aa)
tofu-6Embryonic developmental protein tofu-6; Required maternally for early embryonic cell divisions. May have a role in DNA replication. (365 aa)
evl-20.1ADP-ribosylation factor-like protein 2; GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics; Belongs to the small GTPase superfamily. Arf family. (184 aa)
gsp-2Serine/threonine-protein phosphatase PP1-beta; Serine/threonine-protein phosphatase essential for chromosomal dynamics during meiosis and mitosis. Antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Essential for embryogenesis (By similarity). (333 aa)
cyd-1Protein CBR-CYD-1; Belongs to the cyclin family. (427 aa)
cdk-4Cyclin-dependent kinase CDK-4/6; Belongs to the protein kinase superfamily. (345 aa)
cye-1G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] (518 aa)
CBG23575Protein CBG23575. (162 aa)
CBG23609Protein CBG23609. (413 aa)
CBG23700Protein CBG23700. (246 aa)
hcp-6Condensin-2 complex subunit. (1739 aa)
CBG23873Protein CBG23873; Belongs to the CDC50/LEM3 family. (361 aa)
mlc-3Protein CBR-MLC-3. (153 aa)
CBG24443Protein CBG24443. (93 aa)
CBG24444Protein CBG24444. (376 aa)
CBG24445Protein CBG24445. (368 aa)
knl-1Kinetochore null protein 1; Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division. Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy. Has a role in the correct localization of spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1. Required for the recruitment of spindle-assembly checkpoint components bub-1 and mdf-1/2 to unattached ki [...] (957 aa)
CBG24625Protein CBG24625. (94 aa)
goa-1Protein CBR-GOA-1. (323 aa)
CBG24829Protein CBG24829. (235 aa)
CBG24830Protein CBG24830. (451 aa)
CBG00040Protein CBG00040. (1622 aa)
CBG00165Protein CBG00165. (652 aa)
emb-27Protein CBR-EMB-27. (669 aa)
ran-3Protein CBR-RAN-3. (572 aa)
puf-5Protein CBR-PUF-5. (453 aa)
CBG00631Protein CBG00631. (127 aa)
zyg-9Protein CBR-ZYG-9. (1427 aa)
mop-25.2Protein CBR-MOP-25.2. (338 aa)
cdc-25.4Protein CBR-CDC-25.4. (252 aa)
fbxa-137Protein CBR-FBXA-137. (321 aa)
CBG01362Protein CBG01362. (461 aa)
CBG01364Protein CBG01364. (468 aa)
CBG01365Protein CBG01365. (484 aa)
CBG01375Protein CBG01375. (504 aa)
atg-18Protein CBR-ATG-18. (406 aa)
CBG01467Protein CBG01467. (383 aa)
cyp-31a2Protein CBR-CYP-31A3; Belongs to the cytochrome P450 family. (495 aa)
Cbr-csn-3Protein CBR-CSN-3. (750 aa)
tcl-2Protein CBR-TCL-2. (441 aa)
pig-1Non-specific serine/threonine protein kinase. (704 aa)
CBG02011Protein CBG02011. (556 aa)
CBG02130Protein CBG02130. (188 aa)
CBG02137Protein CBG02137. (97 aa)
CBG02150Protein CBG02150. (727 aa)
CBG02161Protein CBG02161. (372 aa)
CBG02162Protein CBG02162. (372 aa)
CBG02167Protein CBG02167. (372 aa)
CBG02169Protein CBG02169; Belongs to the actin family. (353 aa)
CBG02222Protein CBG02222. (436 aa)
ska-1Spindle and kinetochore-associated protein 1 homolog; Component of the ska-1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The ska-1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtu [...] (239 aa)
ptc-1Protein CBG03294. (1434 aa)
szy-20Protein CBR-SZY-20. (514 aa)
Cbr-rha-1Protein CBR-RHA-1. (1402 aa)
ebp-2Protein CBR-EBP-2. (306 aa)
npp-19Protein CBR-NPP-19. (372 aa)
ect-2Protein CBR-ECT-2. (958 aa)
mix-1Protein CBR-MIX-1. (1296 aa)
mat-2Protein CBR-MAT-2. (1853 aa)
npp-5Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (827 aa)
top-2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1482 aa)
atg-16.2Protein CBR-ATG-16.2. (552 aa)
lin-23Protein CBR-LIN-23. (682 aa)
ani-2Protein CBR-ANI-2. (1038 aa)
egl-44Protein CBR-EGL-44. (472 aa)
ify-1Protein CBR-IFY-1. (281 aa)
cdc-14.2Protein CBR-CDC-14. (1044 aa)
cdc-14.1Protein CBG02450. (698 aa)
fzy-1Protein CBR-FZY-1. (521 aa)
dsh-2Protein CBR-DSH-2. (784 aa)
kca-1Protein CBR-KCA-1. (423 aa)
dpy-26Protein CBR-DPY-26. (1261 aa)
rack-1Protein CBR-RACK-1. (325 aa)
egl-20Protein CBR-EGL-20. (398 aa)
CBG03557Leishmanolysin-like peptidase. (505 aa)
CBG03559Protein CBG03559. (277 aa)
tim-1Protein CBR-TIM-1. (1404 aa)
CBG03913Protein CBG03913. (215 aa)
cpg-1Chondroitin proteoglycan 1; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin (By similarity). (686 aa)
let-502Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization (By similarity). (1194 aa)
Cbr-rmd-6Protein CBR-RMD-6. (255 aa)
rnt-1Protein CBR-RNT-1. (312 aa)
uri-1Protein CBR-URI-1. (447 aa)
mei-1Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. This activity may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. (484 aa)
lin-17Protein CBR-LIN-17; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
pop-1Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage- derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. Belongs t [...] (439 aa)
lem-3Protein CBR-LEM-3. (698 aa)
ensa-1Protein CBR-ENSA-1; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (174 aa)
cdk-7Protein CBR-CDK-7; Belongs to the protein kinase superfamily. (343 aa)
icp-1Protein CBR-ICP-1. (516 aa)
tac-1Protein CBR-TAC-1. (262 aa)
scc-1Protein CBR-SCC-1. (633 aa)
vps-33.2Protein CBR-VPS-33.2; Belongs to the STXBP/unc-18/SEC1 family. (670 aa)
CBG04461Protein CBG04461. (433 aa)
unc-61Protein CBR-UNC-61; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (532 aa)
szy-2Protein CBG05166. (184 aa)
CBG05204Protein CBG05204. (505 aa)
CBG05213Protein CBG05213. (160 aa)
CBG05455Protein CBG05455. (705 aa)
zen-4Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (779 aa)
lag-1Protein CBR-LAG-1. (681 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
maph-9Protein CBG05783. (502 aa)
lip-1Protein CBR-LIP-1. (376 aa)
puf-6.3Protein CBG06390. (340 aa)
cdc-25.2Protein CBG06594. (540 aa)
CBG06875Protein CBG06875. (310 aa)
cya-1Protein CBG06936; Belongs to the cyclin family. (467 aa)
CBG07665Protein CBG07665. (296 aa)
CBG07602Protein CBG07602. (452 aa)
gfi-3Protein CBR-GFI-3. (794 aa)
ztf-6Protein CBR-ZTF-6. (464 aa)
rei-2Protein CBG08062. (432 aa)
cdc-25.3Protein CBR-CDC-25.3. (302 aa)
cdc-48.3Protein CBR-CDC-48.3. (736 aa)
apr-1APC-related protein 1; Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing the polarity of the mother cel [...] (1171 aa)
nmy-2Protein CBR-NMY-2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2051 aa)
CBG08365Protein CBG08365. (208 aa)
cpg-2.1Protein CBG08448. (487 aa)
scc-3Protein CBR-SCC-3. (1122 aa)
par-6Protein CBR-PAR-6. (305 aa)
CBG08925Protein CBG08925; Belongs to the actin family. (389 aa)
him-10Protein CBR-HIM-10. (637 aa)
CBG09061Protein CBG09061. (248 aa)
nop-1Protein CBG09033. (752 aa)
npp-10Protein CBR-NPP-10. (1684 aa)
cyk-3Protein CBR-CYK-3. (1190 aa)
par-3Protein CBR-PAR-3. (1332 aa)
plk-1Serine/threonine-protein kinase PLK. (661 aa)
lig-1DNA ligase. (797 aa)
apc-10Protein CBR-APC-10. (144 aa)
klc-1Protein CBG09436. (530 aa)
CBG09367Protein CBG09367. (471 aa)
klc-2Protein CBR-KLC-2. (522 aa)
CBG09790Protein CBG09790. (516 aa)
mlc-4Protein CBR-MLC-4. (172 aa)
bub-1Protein CBR-BUB-1. (971 aa)
rmd-1Protein CBR-RMD-1. (226 aa)
cdk-1Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). (326 aa)
let-99Protein CBR-LET-99. (710 aa)
Cbr-gpr-2Protein CBR-GPR-2. (532 aa)
Cbr-tag-300Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (501 aa)
mat-1Protein CBR-MAT-1. (746 aa)
CBG10973Protein CBG10973. (372 aa)
CBG10974Protein CBG10974. (318 aa)
mes-2Protein CBR-MES-2. (930 aa)
unc-104Protein CBR-UNC-104; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1699 aa)
CBG11385Protein CBG11385. (307 aa)
CBG11284Protein CBG11284. (426 aa)
CBG11256Protein CBG11256. (254 aa)
ani-1Protein CBR-ANI-1. (1199 aa)
pph-4.1Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] (333 aa)
CBG11789Protein CBG11789. (244 aa)
puf-6.2Protein CBG11800. (437 aa)
mau-2Protein CBR-MAU-2. (427 aa)
capg-1Protein CBR-CAPG-1. (1270 aa)
ptr-2Protein CBR-PTR-2. (948 aa)
egg-4Protein CBR-EGG-4. (752 aa)
lin-44Abnormal cell lineage protein 44; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Affects male tail development, vulval precursor cell specification and egg laying. Involved in morphogenesis by influencing polarity of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites. Controls spindle orientation in B-gamma cell division during male copulatory spicule development. Involved in specification of the P7.p lineage during vulval development. Has a role in providing polarity and default lin-17 [...] (341 aa)
CBG12075Protein CBG12075. (611 aa)
CBG12081Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (105 aa)
prg-1Protein CBR-PRG-1; Belongs to the argonaute family. (826 aa)
csnk-1Protein CBR-CSNK-1; Belongs to the protein kinase superfamily. (460 aa)
cdc-6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (531 aa)
tyr-1.2Protein CBR-TYR-1. (618 aa)
tyr-1.1Protein CBG12272. (594 aa)
ran-2Protein CBR-RAN-2. (975 aa)
kle-2Protein CBR-KLE-2. (958 aa)
CBG12411Protein CBG12411. (518 aa)
cdc-26Protein CBR-CDC-26. (186 aa)
cdc-5lProtein CBG12532. (790 aa)
mat-3Protein CBR-MAT-3. (667 aa)
knl-2Protein CBR-KNL-2. (810 aa)
cdc-25.1Protein CBR-CDC-25.1. (615 aa)
spg-20Protein CBG12661. (476 aa)
mei-2Protein CBG12676. (274 aa)
cdc-42Protein CBR-CDC-42. (191 aa)
gld-3Protein CBR-GLD-3. (956 aa)
CBG13129Protein CBG13129. (1142 aa)
insc-1Protein CBR-INSC-1. (639 aa)
puf-6.1Protein CBG13175. (394 aa)
smc-3Protein CBR-SMC-3. (1241 aa)
CBG13261Protein CBG13261. (173 aa)
such-1Protein CBR-SUCH-1. (769 aa)
ham-1Protein CBR-HAM-1. (376 aa)
CBG13581Protein CBG13581. (651 aa)
rho-1Protein CBR-RHO-1. (192 aa)
CBG13699Protein CBG13699. (277 aa)
lem-4Protein CBG13985. (563 aa)
jtr-1Protein CBR-JTR-1. (133 aa)
mdf-2Protein CBR-MDF-2. (203 aa)
mltn-13Protein CBR-MLTN-13. (752 aa)
CBG14574Protein CBG14574. (324 aa)
egl-13Protein CBR-EGL-13. (482 aa)
cdk-2Protein CBR-CDK-2; Belongs to the protein kinase superfamily. (340 aa)
pid-3Protein CBG14989. (304 aa)
CBG15077Protein CBG15077. (454 aa)
CBG15203Protein CBG15203. (648 aa)
par-2Protein CBR-PAR-2. (647 aa)
cks-1Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Has a role in the exit from M phase during early mitotic cell division. More specifically, thought to act by the degrading B-type cyclins that causes breakdown of nuclear envelope and exit mitosis (By similarity). (94 aa)
CBG15976Protein CBG15976. (609 aa)
CBG16219Protein CBG16219. (458 aa)
rod-1Protein CBR-ROD-1. (2213 aa)
CBG16744Protein CBG16744. (663 aa)
efhc-1Protein CBG17221. (461 aa)
czw-1Protein CBR-CZW-1. (778 aa)
CBG17703Protein CBG17703. (296 aa)
mlc-5Protein CBR-MLC-5. (142 aa)
cyk-4Protein CBR-CYK-4. (676 aa)
strd-1Protein CBR-STRD-1. (385 aa)
cul-2Protein CBR-CUL-2; Belongs to the cullin family. (850 aa)
ran-1GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
cnt-2Protein CBR-CNT-2. (1161 aa)
CBG18353Protein CBG18353. (186 aa)
atx-2Protein CBR-ATX-2. (1051 aa)
tost-1Protein CBG17949. (137 aa)
mel-28Protein CBR-MEL-28. (1559 aa)
apc-11Protein CBR-APC-11. (134 aa)
erh-2Protein CBG18033. (111 aa)
smc-4Protein CBR-SMC-4. (1572 aa)
cyy-1Protein CBR-CYY-1; Belongs to the cyclin family. (357 aa)
unc-116Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (843 aa)
CBG18556Protein CBG18556. (224 aa)
CBG18766Protein CBG18766. (102 aa)
egl-46Protein CBR-EGL-46. (283 aa)
spdl-1Protein CBR-SPDL-1. (501 aa)
rbx-1Protein CBR-RBX-1. (110 aa)
CBG19457Protein CBG19457. (152 aa)
dlc-1Dynein light chain. (89 aa)
unc-59Protein CBR-UNC-59; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (455 aa)
bec-1Protein CBR-BEC-1. (375 aa)
cpg-2Chondroitin proteoglycan 2; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin (By similarity). (491 aa)
rei-1Protein CBG20214. (245 aa)
pelo-1Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (382 aa)
cam-1Protein CBR-CAM-1. (916 aa)
CBG20268Protein CBG20268; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (448 aa)
CBG20238Protein CBG20238. (157 aa)
cyp-42a1Protein CBR-CYP-42A1; Belongs to the cytochrome P450 family. (512 aa)
CBG20324Protein CBG20324. (353 aa)
CBG20333Protein CBG20333. (211 aa)
sptf-3Protein CBR-SPTF-3. (374 aa)
him-1Protein CBR-HIM-1. (1289 aa)
CBG20515Protein CBG20515. (374 aa)
egg-3Protein CBR-EGG-3. (419 aa)
Cbr-tag-10Protein CBR-TAG-10. (451 aa)
csc-1Protein CBR-CSC-1. (204 aa)
bub-3Protein CBR-BUB-3. (342 aa)
CBG20697Protein CBG20697. (173 aa)
spat-1Protein CBR-SPAT-1. (542 aa)
lis-1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (390 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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