(28 nodes) Regulation of synapse assembly network (Caenorhabditis briggsae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	kpc-1	Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
	CBG00329	Protein CBG00329. (294 aa)
	rpm-1	Protein CBR-RPM-1. (3789 aa)
	CBG01371	Protein CBG01371; Belongs to the protein kinase superfamily. (372 aa)
	casy-1	Protein CBR-CASY-1. (983 aa)
	vps-35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (858 aa)
	clr-1	Protein CBR-CLR-1. (1471 aa)
	gon-1	Protein CBR-GON-1. (2153 aa)
	syd-2	Protein CBR-SYD-2. (1152 aa)
	CBG05428	Protein CBG05428. (819 aa)
	pdk-1	Protein CBR-PDK-1. (644 aa)
	egl-21	Protein CBR-EGL-21. (473 aa)
	akt-1	Non-specific serine/threonine protein kinase. (605 aa)
	egl-3	Protein CBR-EGL-3; Belongs to the peptidase S8 family. (662 aa)
	prk-2	Protein CBR-PRK-2; Belongs to the protein kinase superfamily. (450 aa)
	unc-6	Protein CBR-UNC-6. (621 aa)
	unc-104	Protein CBR-UNC-104; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1699 aa)
	daf-16	Protein CBR-DAF-16. (497 aa)
	bli-4	Protein CBR-BLI-4; Belongs to the peptidase S8 family. (730 aa)
	mak-2	Protein CBR-MAK-2; Belongs to the protein kinase superfamily. (366 aa)
	unc-40	Protein CBR-UNC-40. (1407 aa)
	CBG15618	Protein CBG15618. (460 aa)
	daf-2	Protein CBR-DAF-2. (1840 aa)
	ppm-2	Protein CBG18025. (352 aa)
	cyy-1	Protein CBR-CYY-1; Belongs to the cyclin family. (357 aa)
	fsn-1	F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
	aex-5	Protein CBR-AEX-5. (541 aa)
	cdk-5	Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG01371	akt-1	A8WQ92	A8X8T0	Protein CBG01371; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.451
CBG15618	akt-1	A8XME2	A8X8T0	Protein CBG15618.	Non-specific serine/threonine protein kinase.	0.844
CBG15618	daf-16	A8XME2	A8XFP9	Protein CBG15618.	Protein CBR-DAF-16.	0.641
aex-5	egl-21	A8XWH5	A8X6C1	Protein CBR-AEX-5.	Protein CBR-EGL-21.	0.510
akt-1	CBG01371	A8X8T0	A8WQ92	Non-specific serine/threonine protein kinase.	Protein CBG01371; Belongs to the protein kinase superfamily.	0.451
akt-1	CBG15618	A8X8T0	A8XME2	Non-specific serine/threonine protein kinase.	Protein CBG15618.	0.844
akt-1	daf-16	A8X8T0	A8XFP9	Non-specific serine/threonine protein kinase.	Protein CBR-DAF-16.	0.992
akt-1	daf-2	A8X8T0	A8XMN1	Non-specific serine/threonine protein kinase.	Protein CBR-DAF-2.	0.537
akt-1	mak-2	A8X8T0	A8XIW8	Non-specific serine/threonine protein kinase.	Protein CBR-MAK-2; Belongs to the protein kinase superfamily.	0.415
akt-1	pdk-1	A8X8T0	A8X5P7	Non-specific serine/threonine protein kinase.	Protein CBR-PDK-1.	0.889
akt-1	prk-2	A8X8T0	A8X9T8	Non-specific serine/threonine protein kinase.	Protein CBR-PRK-2; Belongs to the protein kinase superfamily.	0.451
cdk-5	cyy-1	A8XZM0	A8XT42	Protein CBR-CDK-5; Belongs to the protein kinase superfamily.	Protein CBR-CYY-1; Belongs to the cyclin family.	0.778
cdk-5	syd-2	A8XZM0	A8WXR6	Protein CBR-CDK-5; Belongs to the protein kinase superfamily.	Protein CBR-SYD-2.	0.633
clr-1	daf-2	A8WUE3	A8XMN1	Protein CBR-CLR-1.	Protein CBR-DAF-2.	0.506
clr-1	syd-2	A8WUE3	A8WXR6	Protein CBR-CLR-1.	Protein CBR-SYD-2.	0.685
clr-1	unc-40	A8WUE3	A8XKZ7	Protein CBR-CLR-1.	Protein CBR-UNC-40.	0.582
cyy-1	cdk-5	A8XT42	A8XZM0	Protein CBR-CYY-1; Belongs to the cyclin family.	Protein CBR-CDK-5; Belongs to the protein kinase superfamily.	0.778
daf-16	CBG15618	A8XFP9	A8XME2	Protein CBR-DAF-16.	Protein CBG15618.	0.641
daf-16	akt-1	A8XFP9	A8X8T0	Protein CBR-DAF-16.	Non-specific serine/threonine protein kinase.	0.992
daf-16	daf-2	A8XFP9	A8XMN1	Protein CBR-DAF-16.	Protein CBR-DAF-2.	0.996