STRINGSTRING
CBG11917 CBG11917 CBG11828 CBG11828 unc-52 unc-52 CBG10901 CBG10901 gei-15 gei-15 dyc-1 dyc-1 pat-2 pat-2 unc-132 unc-132 unc-112 unc-112 CBG03662 CBG03662 pat-3 pat-3 trx-3 trx-3 ced-3 ced-3 CBG00891 CBG00891 CBG00230 CBG00230 CBG24504 CBG24504 stn-1 stn-1 ced-4 ced-4 smo-1 smo-1 CBG25832 CBG25832 CBG26587 CBG26587 clp-1 clp-1 cpl-1 cpl-1 pat-6 pat-6 mks-1 mks-1 dyb-1 dyb-1 unc-70 unc-70 CBG17636 CBG17636 egl-15 egl-15 sur-7 sur-7 Cbr-pat-4 Cbr-pat-4 Cbr-dys-1 Cbr-dys-1 dys-1 dys-1 cav-1 cav-1 bet-1 bet-1 unc-97 unc-97 lfi-1 lfi-1 Cbr-kel-10 Cbr-kel-10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG11917Protein CBG11917. (165 aa)
CBG11828Protein CBG11828. (55 aa)
unc-52Protein CBR-UNC-52. (2481 aa)
CBG10901Protein CBG10901. (360 aa)
gei-15Protein CBR-GEI-15. (408 aa)
dyc-1Protein CBR-DYC-1. (985 aa)
pat-2Integrin alpha pat-2; Required for muscle development probably through the regulation of the actin-myosin cytoskeleton. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52. Required for distal tip cell migration and dorsal pathfinding. Required for egg-laying. May play a role in cell motility and cell-cell interactions. (1224 aa)
unc-132Protein CBR-UNC-132. (474 aa)
unc-112Protein CBR-UNC-112. (720 aa)
CBG03662Protein CBG03662. (149 aa)
pat-3Integrin beta; Belongs to the integrin beta chain family. (818 aa)
trx-3Protein CBR-TRX-3. (157 aa)
ced-3Protein CBR-CED-3; Belongs to the peptidase C14A family. (508 aa)
CBG00891Protein CBG00891. (150 aa)
CBG00230Protein CBG00230. (598 aa)
CBG24504Protein CBG24504. (288 aa)
stn-1Protein CBR-STN-1. (422 aa)
ced-4Cell death protein 4; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to induce caspase ced-3 autoproteolytic cleavage and activation. Also forms an holoenzyme with processed ced-3 enhancing ced-3 activity. Component of the egl-1, ced-9, ced-4 and ced- 3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During [...] (569 aa)
smo-1Small ubiquitin-related modifier. (95 aa)
CBG25832Protein CBG25832. (61 aa)
CBG26587Protein CBG26587. (599 aa)
clp-1Protein CBR-CLP-1; Belongs to the peptidase C2 family. (938 aa)
cpl-1Protein CBR-CPL-1; Belongs to the peptidase C1 family. (336 aa)
pat-6Protein CBR-PAT-6. (379 aa)
mks-1Protein CBR-MKS-1. (384 aa)
dyb-1Dystrobrevin. (622 aa)
unc-70Spectrin beta chain; Belongs to the spectrin family. (2370 aa)
CBG17636Protein CBG17636; Belongs to the peptidase C2 family. (173 aa)
egl-15Receptor protein-tyrosine kinase. (1192 aa)
sur-7Protein CBR-SUR-7. (365 aa)
Cbr-pat-4Protein CBR-PAT-4. (278 aa)
Cbr-dys-1Protein CBR-DYS-1. (2353 aa)
dys-1Protein CBG15371. (1276 aa)
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
bet-1Protein CBR-BET-1. (772 aa)
unc-97LIM domain-containing protein. (353 aa)
lfi-1Protein CBR-LFI-1. (2488 aa)
Cbr-kel-10Protein CBR-KEL-10. (524 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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