STRINGSTRING
rba-1 rba-1 dma-1 dma-1 Cbr-hpo-40 Cbr-hpo-40 lin-22 lin-22 vhp-1 vhp-1 rig-6 rig-6 cdc-14.2 cdc-14.2 pmk-3 pmk-3 cif-1 cif-1 ref-1 ref-1 gld-1 gld-1 cdc-14.1 cdc-14.1 vha-19 vha-19 cnd-1 cnd-1 nfm-1 nfm-1 cdk-5 cdk-5 CBG21739 CBG21739 oma-2 oma-2 lin-41 lin-41 gsa-1 gsa-1 pin-2 pin-2 CBG22476 CBG22476 CBG23464 CBG23464 rnp-1 rnp-1 CBG13515 CBG13515 CBG26587 CBG26587 CBG25825 CBG25825 CBG02851 CBG02851 Cbr-sax-7 Cbr-sax-7 unc-53 unc-53 mab-20 mab-20 plx-2 plx-2 fem-3 fem-3 fog-3 fog-3 unc-5 unc-5 smp-1 smp-1 glo-4 glo-4 gck-1 gck-1 mag-1 mag-1 pde-6 pde-6 fsn-1 fsn-1 cyy-1 cyy-1 rnp-4 rnp-4 ppm-2 ppm-2 atx-2 atx-2 dbn-1 dbn-1 CBG16766 CBG16766 mek-1 mek-1 kpc-1 kpc-1 pgrn-1 pgrn-1 unc-40 unc-40 kin-2 kin-2 unc-97 unc-97 mls-2 mls-2 CBG14420 CBG14420 ceh-18 ceh-18 lin-32 lin-32 CBG14033 CBG14033 ngn-1 ngn-1 mak-2 mak-2 plx-1 plx-1 efa-6 efa-6 grdn-1 grdn-1 sig-7 sig-7 tyr-1.1 tyr-1.1 tyr-1.2 tyr-1.2 tiam-1 tiam-1 Cbr-unc-13 Cbr-unc-13 unc-13 unc-13 unc-73 unc-73 smp-2 smp-2 zag-1 zag-1 lin-52 lin-52 cpi-2 cpi-2 mlk-1 mlk-1 CBG08400 CBG08400 slt-1 slt-1 lin-9 lin-9 pam-1 pam-1 mnr-1 mnr-1 CBG04481 CBG04481 vab-3 vab-3 CBG03842 CBG03842
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rba-1Protein CBR-RBA-1. (418 aa)
dma-1Protein CBR-DMA-1. (582 aa)
Cbr-hpo-40Protein CBR-HPO-40. (608 aa)
lin-22Protein CBR-LIN-22. (164 aa)
vhp-1Protein CBR-VHP-1. (672 aa)
rig-6Protein CBR-RIG-6. (1297 aa)
cdc-14.2Protein CBR-CDC-14. (1044 aa)
pmk-3Mitogen-activated protein kinase. (466 aa)
cif-1COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulat [...] (390 aa)
ref-1Protein CBR-REF-1. (375 aa)
gld-1Protein CBR-GLD-1. (467 aa)
cdc-14.1Protein CBG02450. (698 aa)
vha-19Protein CBR-VHA-19. (453 aa)
cnd-1Protein CBR-CND-1. (198 aa)
nfm-1Protein CBR-NFM-1. (690 aa)
cdk-5Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa)
CBG21739Protein CBG21739. (192 aa)
oma-2Protein CBR-OMA-2. (379 aa)
lin-41Protein CBR-LIN-41. (934 aa)
gsa-1Protein CBR-GSA-1. (326 aa)
pin-2Protein CBR-PIN-2. (328 aa)
CBG22476Protein CBG22476. (413 aa)
CBG23464Protein CBG23464. (800 aa)
rnp-1Protein CBR-RNP-1. (286 aa)
CBG13515Protein CBG13515. (589 aa)
CBG26587Protein CBG26587. (599 aa)
CBG25825Protein CBG25825. (145 aa)
CBG02851Protein CBG02851. (560 aa)
Cbr-sax-7Protein CBR-SAX-7. (1402 aa)
unc-53Protein CBR-UNC-53, isoform a. (1778 aa)
mab-20Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (656 aa)
plx-2Plexin-2; Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis. (1773 aa)
fem-3Sex-determination protein fem-3; Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite animals), it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. (409 aa)
fog-3Protein CBR-FOG-3. (261 aa)
unc-5Protein CBR-UNC-5. (922 aa)
smp-1Protein CBR-SMP-1; Belongs to the semaphorin family. (714 aa)
glo-4Protein CBR-GLO-4. (1392 aa)
gck-1Protein CBR-GCK-1. (898 aa)
mag-1Protein CBR-MAG-1. (153 aa)
pde-6Phosphodiesterase. (705 aa)
fsn-1F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
cyy-1Protein CBR-CYY-1; Belongs to the cyclin family. (357 aa)
rnp-4RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (142 aa)
ppm-2Protein CBG18025. (352 aa)
atx-2Protein CBR-ATX-2. (1051 aa)
dbn-1Protein CBG18266. (672 aa)
CBG16766Protein CBG16766. (1020 aa)
mek-1Protein CBR-MEK-1. (463 aa)
kpc-1Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
pgrn-1Protein CBR-PGRN-1. (291 aa)
unc-40Protein CBR-UNC-40. (1407 aa)
kin-2Protein CBR-KIN-2. (366 aa)
unc-97LIM domain-containing protein. (353 aa)
mls-2Protein CBR-MLS-2. (332 aa)
CBG14420Protein CBG14420. (182 aa)
ceh-18POU domain protein. (545 aa)
lin-32Protein CBR-LIN-32. (148 aa)
CBG14033Protein CBG14033. (156 aa)
ngn-1Protein CBR-NGN-1. (200 aa)
mak-2Protein CBR-MAK-2; Belongs to the protein kinase superfamily. (366 aa)
plx-1Protein CBR-PLX-1. (1959 aa)
efa-6Protein CBR-EFA-6. (836 aa)
grdn-1Protein CBG12901. (1474 aa)
sig-7Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (434 aa)
tyr-1.1Protein CBG12272. (594 aa)
tyr-1.2Protein CBR-TYR-1. (618 aa)
tiam-1Protein CBR-CGEF-2. (610 aa)
Cbr-unc-13Protein CBG11945. (394 aa)
unc-13Protein CBR-UNC-13. (2250 aa)
unc-73Protein CBR-UNC-73. (1618 aa)
smp-2Protein CBR-SMP-2; Belongs to the semaphorin family. (689 aa)
zag-1Protein CBR-ZAG-1. (618 aa)
lin-52Protein CBR-LIN-52. (162 aa)
cpi-2Protein CBR-CPI-2. (144 aa)
mlk-1Protein CBR-MLK-1. (1091 aa)
CBG08400Protein CBG08400. (668 aa)
slt-1Protein CBR-SLT-1. (1376 aa)
lin-9Protein CBR-LIN-9. (641 aa)
pam-1Aminopeptidase. (899 aa)
mnr-1Protein CBG05639. (506 aa)
CBG04481Protein CBG04481. (254 aa)
vab-3Protein CBR-VAB-3. (290 aa)
CBG03842Protein CBG03842. (438 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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