STRINGSTRING
jip-1 jip-1 ubr-5 ubr-5 eya-1 eya-1 ubc-12 ubc-12 CBG18697 CBG18697 fsn-1 fsn-1 ula-1 ula-1 pdr-1 pdr-1 pxn-2 pxn-2 mek-1 mek-1 rfl-1 rfl-1 CBG16442 CBG16442 parg-2 parg-2 CBG16219 CBG16219 CBG16281 CBG16281 CBG16282 CBG16282 CBG16285 CBG16285 CBG15077 CBG15077 cav-1 cav-1 tns-1 tns-1 octr-1 octr-1 ddr-1 ddr-1 glit-1 glit-1 tsp-17 tsp-17 ddr-2 ddr-2 mak-2 mak-2 manf-1 manf-1 efa-6 efa-6 ubh-4 ubh-4 swsn-7 swsn-7 CBG13303 CBG13303 ned-8 ned-8 let-607 let-607 gei-17 gei-17 CBG11949 CBG11949 lin-44 lin-44 polh-1 polh-1 CBG11256 CBG11256 CBG11284 CBG11284 svh-2 svh-2 pdi-6 pdi-6 ubql-1 ubql-1 emb-9 emb-9 unc-16 unc-16 sqv-3 sqv-3 zmp-2 zmp-2 cni-1 cni-1 ppm-1.a ppm-1.a CBG09061 CBG09061 scc-3 scc-3 mlk-1 mlk-1 CBG08098 CBG08098 gale-1 gale-1 tap-1 tap-1 CBG07602 CBG07602 pqn-85 pqn-85 nol-2 nol-2 CBG07104 CBG07104 CBG06875 CBG06875 egl-8 egl-8 jnk-1 jnk-1 flp-13 flp-13 CBG06087 CBG06087 shc-1 shc-1 pept-1 pept-1 abl-1 abl-1 CBG04461 CBG04461 CBG04453 CBG04453 pat-3 pat-3 vhp-1 vhp-1 CBG02464 CBG02464 CBG02604 CBG02604 npp-5 npp-5 rtel-1 rtel-1 nlp-2 nlp-2 pmk-3 pmk-3 faah-1 faah-1 tpa-1 tpa-1 wapl-1 wapl-1 CBG01796 CBG01796 smk-1 smk-1 pxn-1 pxn-1 CBG01375 CBG01375 CBG01365 CBG01365 CBG01364 CBG01364 CBG01362 CBG01362 rhy-1 rhy-1 CBG24830 CBG24830 CBG24829 CBG24829 CBG24757 CBG24757 goa-1 goa-1 nmad-1 nmad-1 trf-2 trf-2 CBG23700 CBG23700 CBG23609 CBG23609 rbx-1 rbx-1 CBG19457 CBG19457 set-1 set-1 CBG20238 CBG20238 CBG20324 CBG20324 CBG20333 CBG20333 CBG21002 CBG21002 prmt-5 prmt-5 trf-1 trf-1 praf-3 praf-3 ulp-1 ulp-1 CBG21334 CBG21334 CBG21463 CBG21463 CBG21964 CBG21964 plep-1 plep-1 CBG22010 CBG22010 egl-30 egl-30 CBG22453 CBG22453 CBG22502 CBG22502 dmsr-1 dmsr-1 efhd-1 efhd-1 CBG13515 CBG13515 CBG27374 CBG27374 CBG27110 CBG27110 CBG26587 CBG26587 CBG25215 CBG25215 CBG26279 CBG26279 CBG00051 CBG00051 CBG27040 CBG27040 crt-1 crt-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
jip-1Protein CBR-JIP-1. (385 aa)
ubr-5Protein CBG18920. (2963 aa)
eya-1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (483 aa)
ubc-12Protein CBR-UBC-12; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
CBG18697Protein CBG18697. (355 aa)
fsn-1F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
ula-1NEDD8-activating enzyme E1 regulatory subunit. (550 aa)
pdr-1E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (385 aa)
pxn-2Protein CBR-PXN-2. (1366 aa)
mek-1Protein CBR-MEK-1. (463 aa)
rfl-1Protein CBR-RFL-1. (430 aa)
CBG16442Protein CBG16442. (80 aa)
parg-2Protein CBR-PME-3. (331 aa)
CBG16219Protein CBG16219. (458 aa)
CBG16281Protein CBG16281. (224 aa)
CBG16282Protein CBG16282. (184 aa)
CBG16285Protein CBG16285. (205 aa)
CBG15077Protein CBG15077. (454 aa)
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
tns-1Protein CBR-TAG-163. (938 aa)
octr-1Protein CBR-OCTR-1; Belongs to the G-protein coupled receptor 1 family. (406 aa)
ddr-1Protein CBR-DDR-1. (821 aa)
glit-1Protein CBR-GLIT-1. (738 aa)
tsp-17Tetraspanin. (277 aa)
ddr-2Protein CBR-DDR-2. (898 aa)
mak-2Protein CBR-MAK-2; Belongs to the protein kinase superfamily. (366 aa)
manf-1Protein CBG13529. (169 aa)
efa-6Protein CBR-EFA-6. (836 aa)
ubh-4Ubiquitin carboxyl-terminal hydrolase. (326 aa)
swsn-7Protein CBR-SWSN-7. (1221 aa)
CBG13303Protein CBG13303. (602 aa)
ned-8Protein CBR-NED-8. (76 aa)
let-607Protein CBR-LET-607. (686 aa)
gei-17Protein CBR-GEI-17. (675 aa)
CBG11949Protein CBG11949; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
lin-44Abnormal cell lineage protein 44; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Affects male tail development, vulval precursor cell specification and egg laying. Involved in morphogenesis by influencing polarity of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites. Controls spindle orientation in B-gamma cell division during male copulatory spicule development. Involved in specification of the P7.p lineage during vulval development. Has a role in providing polarity and default lin-17 [...] (341 aa)
polh-1Protein CBR-POLH-1. (594 aa)
CBG11256Protein CBG11256. (254 aa)
CBG11284Protein CBG11284. (426 aa)
svh-2Protein CBG10839; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1120 aa)
pdi-6Protein CBR-TAG-320; Belongs to the protein disulfide isomerase family. (437 aa)
ubql-1Protein CBG10788. (525 aa)
emb-9Protein CBR-EMB-9. (1759 aa)
unc-16Protein CBR-UNC-16. (1158 aa)
sqv-3Protein CBR-SQV-3. (285 aa)
zmp-2Protein CBG09830. (489 aa)
cni-1Protein CBR-CNIH-2. (145 aa)
ppm-1.aProtein CBR-PPM-1. (468 aa)
CBG09061Protein CBG09061. (248 aa)
scc-3Protein CBR-SCC-3. (1122 aa)
mlk-1Protein CBR-MLK-1. (1091 aa)
CBG08098Protein CBG08098. (395 aa)
gale-1UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (369 aa)
tap-1Protein CBR-TAP-1. (389 aa)
CBG07602Protein CBG07602. (452 aa)
pqn-85Nipped-B protein. (2140 aa)
nol-2Protein CBR-NOL-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (678 aa)
CBG07104Protein CBG07104. (529 aa)
CBG06875Protein CBG06875. (310 aa)
egl-8Phosphoinositide phospholipase C. (1528 aa)
jnk-1Mitogen-activated protein kinase. (464 aa)
flp-13Protein CBR-FLP-13. (160 aa)
CBG06087Protein CBG06087. (233 aa)
shc-1Protein CBR-SHC-1. (317 aa)
pept-1Protein CBR-PEPT-1. (838 aa)
abl-1Tyrosine-protein kinase. (1211 aa)
CBG04461Protein CBG04461. (433 aa)
CBG04453Protein CBG04453. (452 aa)
pat-3Integrin beta; Belongs to the integrin beta chain family. (818 aa)
vhp-1Protein CBR-VHP-1. (672 aa)
CBG02464Protein CBG02464. (857 aa)
CBG02604Protein CBG02604. (922 aa)
npp-5Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (827 aa)
rtel-1Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (994 aa)
nlp-2Protein CBR-NLP-2. (161 aa)
pmk-3Mitogen-activated protein kinase. (466 aa)
faah-1Protein CBR-FAAH-1. (572 aa)
tpa-1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
wapl-1Protein CBG01692. (742 aa)
CBG01796Protein CBG01796. (564 aa)
smk-1Protein CBR-SMK-1. (1124 aa)
pxn-1Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. (1288 aa)
CBG01375Protein CBG01375. (504 aa)
CBG01365Protein CBG01365. (484 aa)
CBG01364Protein CBG01364. (468 aa)
CBG01362Protein CBG01362. (461 aa)
rhy-1Protein CBR-RHY-1. (504 aa)
CBG24830Protein CBG24830. (451 aa)
CBG24829Protein CBG24829. (235 aa)
CBG24757Protein CBG24757. (616 aa)
goa-1Protein CBR-GOA-1. (323 aa)
nmad-1Protein CBG24043. (291 aa)
trf-2Protein CBG23748. (294 aa)
CBG23700Protein CBG23700. (246 aa)
CBG23609Protein CBG23609. (413 aa)
rbx-1Protein CBR-RBX-1. (110 aa)
CBG19457Protein CBG19457. (152 aa)
set-1Protein CBR-SET-1. (227 aa)
CBG20238Protein CBG20238. (157 aa)
CBG20324Protein CBG20324. (353 aa)
CBG20333Protein CBG20333. (211 aa)
CBG21002Protein CBG21002. (1108 aa)
prmt-5Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (729 aa)
trf-1Protein CBR-TRF-1. (439 aa)
praf-3PRA1 family protein. (189 aa)
ulp-1Protein CBR-ULP-1. (710 aa)
CBG21334Protein CBG21334. (102 aa)
CBG21463Protein CBG21463. (562 aa)
CBG21964Protein CBG21964. (465 aa)
plep-1Protein CBG21963. (508 aa)
CBG22010Sulfhydryl oxidase. (162 aa)
egl-30Protein CBR-EGL-30. (388 aa)
CBG22453Protein CBG22453. (463 aa)
CBG22502Protein CBG22502. (675 aa)
dmsr-1Protein CBR-DMSR-1. (508 aa)
efhd-1Protein CBG02826. (721 aa)
CBG13515Protein CBG13515. (589 aa)
CBG27374Protein CBG27374. (172 aa)
CBG27110Protein CBG27110. (104 aa)
CBG26587Protein CBG26587. (599 aa)
CBG25215Protein CBG25215. (112 aa)
CBG26279Protein CBG26279. (303 aa)
CBG00051Protein CBG00051. (907 aa)
CBG27040Protein CBG27040. (268 aa)
crt-1Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress- induced neurodegeneration (By similarity). (396 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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