STRINGSTRING
casy-1 casy-1 ggr-1 ggr-1 acr-7 acr-7 mgl-2 mgl-2 CBG02060 CBG02060 unc-2 unc-2 moc-1 moc-1 wsp-1 wsp-1 CBG01565 CBG01565 CBG01593 CBG01593 acr-16 acr-16 acr-15 acr-15 glr-5 glr-5 gras-1 gras-1 unc-63 unc-63 acr-6 acr-6 CBG24089 CBG24089 itsn-1 itsn-1 acr-14 acr-14 CBG00939 CBG00939 lev-1 lev-1 syd-1 syd-1 eat-2 eat-2 acr-21.1 acr-21.1 deg-3 deg-3 glr-3 glr-3 glc-2 glc-2 unc-38 unc-38 unc-122 unc-122 CBG18952 CBG18952 moc-2 moc-2 glr-1 glr-1 unc-49 unc-49 dbn-1 dbn-1 dgn-1 dgn-1 lev-8 lev-8 acr-8 acr-8 glr-2 glr-2 apa-2 apa-2 lgc-4 lgc-4 gab-1 gab-1 acc-4 acc-4 acr-21.2 acr-21.2 syx-3 syx-3 acr-10 acr-10 glr-4 glr-4 slo-1 slo-1 acr-11 acr-11 acr-19 acr-19 unc-29 unc-29 Cbr-unc-13 Cbr-unc-13 unc-13 unc-13 sol-1 sol-1 nab-1 nab-1 unc-11 unc-11 acr-5 acr-5 snf-6 snf-6 lgc-46 lgc-46 nmr-2 nmr-2 sphk-1 sphk-1 glr-6 glr-6 acr-3 acr-3 acr-2 acr-2 unc-10 unc-10 dat-1 dat-1 lin-33 lin-33 lin-46 lin-46 lgc-50 lgc-50 syx-4 syx-4 snn-1 snn-1 dop-4 dop-4 syx-2 syx-2 acr-9 acr-9 acr-12 acr-12 pde-2 pde-2 acr-25 acr-25 gar-1 gar-1 unc-64 unc-64
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
casy-1Protein CBR-CASY-1. (983 aa)
ggr-1Protein CBR-GGR-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
acr-7Protein CBR-ACR-7; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (539 aa)
mgl-2Protein CBR-MGL-2. (1083 aa)
CBG02060Protein CBG02060. (342 aa)
unc-2Protein CBR-UNC-2. (1536 aa)
moc-1Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (448 aa)
wsp-1Protein CBR-WSP-1. (785 aa)
CBG01565Protein CBG01565. (188 aa)
CBG01593Protein CBG01593; Belongs to the G-protein coupled receptor 3 family. (1395 aa)
acr-16Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. A subunit of the levamisole-insensitive nicotinic receptor (By similarity); Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. (499 aa)
acr-15Protein CBR-ACR-15. (483 aa)
glr-5Protein CBR-GLR-5. (1149 aa)
gras-1Protein CBG23728. (245 aa)
unc-63Protein CBR-UNC-63. (502 aa)
acr-6Protein CBR-ACR-6. (567 aa)
CBG24089Protein CBG24089; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (247 aa)
itsn-1Protein CBR-ITSN-1. (1099 aa)
acr-14Protein CBR-ACR-14. (520 aa)
CBG00939Protein CBG00939. (578 aa)
lev-1Protein CBR-LEV-1. (506 aa)
syd-1Rho GTPase-activating protein syd-1; Probable GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Regulates the localization and assembly of presynaptic components during presynaptic development and is required for specifying the identity of axons during initial polarity acquisition. In these roles it is thought to act cell autonomously downstream of syg-1 and syg-2 and upstream of syd-2, possibly as a positive regulator of the latter. Required for the control of movement, egg-laying and the correct localization of elks-1 (By similarity). (962 aa)
eat-2Neuronal acetylcholine receptor subunit eat-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity (By similarity). (481 aa)
acr-21.1Protein CBG24892. (450 aa)
deg-3Protein CBR-DEG-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (522 aa)
glr-3Protein CBR-GLR-3. (946 aa)
glc-2Protein CBR-GLC-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa)
unc-38Protein CBR-UNC-38. (510 aa)
unc-122Protein CBR-UNC-122. (555 aa)
CBG18952Protein CBG18952. (188 aa)
moc-2Protein CBR-MOC-2. (170 aa)
glr-1Protein CBR-GLR-1. (978 aa)
unc-49Protein CBR-UNC-49; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (1043 aa)
dbn-1Protein CBG18266. (672 aa)
dgn-1Protein CBR-DGN-1. (594 aa)
lev-8Protein CBR-LEV-8. (545 aa)
acr-8Protein CBR-ACR-8. (453 aa)
glr-2Protein CBR-GLR-2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (967 aa)
apa-2AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (925 aa)
lgc-4Ligand-gated ion channel 4; Acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (636 aa)
gab-1Protein CBR-GAB-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (553 aa)
acc-4Protein CBR-ACC-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (412 aa)
acr-21.2Protein CBR-ACR-21. (576 aa)
syx-3Protein CBR-SYX-3; Belongs to the syntaxin family. (305 aa)
acr-10Protein CBR-ACR-10. (556 aa)
glr-4Protein CBR-GLR-4. (1007 aa)
slo-1Protein CBR-SLO-1. (1165 aa)
acr-11Protein CBR-ACR-11. (460 aa)
acr-19Protein CBR-ACR-19. (555 aa)
unc-29Protein CBR-UNC-29. (491 aa)
Cbr-unc-13Protein CBG11945. (394 aa)
unc-13Protein CBR-UNC-13. (2250 aa)
sol-1Protein CBR-SOL-1. (596 aa)
nab-1Protein CBR-NAB-1. (742 aa)
unc-11Protein CBR-UNC-11. (710 aa)
acr-5Protein CBR-ACR-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (592 aa)
snf-6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (709 aa)
lgc-46Protein CBR-LGC-46; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (509 aa)
nmr-2Protein CBR-NMR-2. (1001 aa)
sphk-1Protein CBR-SPHK-1. (423 aa)
glr-6Protein CBR-GLR-6. (844 aa)
acr-3Protein CBR-ACR-3. (461 aa)
acr-2Protein CBR-ACR-2. (577 aa)
unc-10Protein CBR-UNC-10. (1636 aa)
dat-1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (622 aa)
lin-33Protein CBR-LIN-33. (246 aa)
lin-46Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (413 aa)
lgc-50Protein CBR-LGC-50; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (448 aa)
syx-4Protein CBR-SYX-4; Belongs to the syntaxin family. (293 aa)
snn-1Protein CBR-SNN-1. (448 aa)
dop-4Protein CBR-DOP-4. (509 aa)
syx-2Protein CBR-SYX-2; Belongs to the syntaxin family. (295 aa)
acr-9Protein CBR-ACR-9. (548 aa)
acr-12Protein CBR-ACR-12. (576 aa)
pde-2Phosphodiesterase. (959 aa)
acr-25Protein CBR-ACR-25. (509 aa)
gar-1Protein CBR-GAR-1; Belongs to the G-protein coupled receptor 1 family. (712 aa)
unc-64Syntaxin-1A; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent s [...] (293 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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