STRINGSTRING
CBG22514 CBG22514 cdh-10 cdh-10 pin-2 pin-2 tln-1 tln-1 zig-11 zig-11 rig-6 rig-6 hmp-2 hmp-2 zoo-1 zoo-1 cdh-4 cdh-4 clc-1 clc-1 clc-4 clc-4 zig-3 zig-3 nsy-4 nsy-4 clc-2 clc-2 cdh-9 cdh-9 CBG16382 CBG16382 crb-1 crb-1 CBG16014 CBG16014 him-4 him-4 unc-71 unc-71 CBG15736 CBG15736 cdh-1 cdh-1 zig-12 zig-12 unc-40 unc-40 unc-97 unc-97 dlg-1 dlg-1 CBG14602 CBG14602 glit-1 glit-1 sax-3 sax-3 clc-3 clc-3 jac-1 jac-1 frk-1 frk-1 cdh-3 cdh-3 cdh-5 cdh-5 CBG24230 CBG24230 cdh-12 cdh-12 cdh-7 cdh-7 rig-3 rig-3 bar-1 bar-1 cdh-8 cdh-8 Cbr-fmi-1 Cbr-fmi-1 mics-1 mics-1 ceh-13 ceh-13 wrm-1 wrm-1 let-413 let-413 ncam-1 ncam-1 CBG25184 CBG25184 igcm-1 igcm-1 hmr-1 hmr-1 nlg-1 nlg-1 syg-2 syg-2 CBG06953 CBG06953 pat-2 pat-2 ina-1 ina-1 igdb-3 igdb-3 zig-1 zig-1 zig-7 zig-7 casy-1 casy-1 vab-23 vab-23 CBG11732 CBG11732 CBG29115 CBG29115 CBG24714 CBG24714 vha-12 vha-12 CBG21718 CBG21718 zyx-1 zyx-1 syg-1 syg-1 igcm-3 igcm-3 vab-9 vab-9 hmp-1 hmp-1 wrk-1 wrk-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG22514Protein CBG22514. (887 aa)
cdh-10Protein CBR-CDH-10. (1388 aa)
pin-2Protein CBR-PIN-2. (328 aa)
tln-1Protein CBG22153. (1036 aa)
zig-11Protein CBG21818. (306 aa)
rig-6Protein CBR-RIG-6. (1297 aa)
hmp-2Protein CBR-HMP-2. (686 aa)
zoo-1Protein CBR-ZOO-1. (1208 aa)
cdh-4Protein CBR-CDH-4. (4389 aa)
clc-1Protein CBR-CLC-1. (182 aa)
clc-4Protein CBR-CLC-4. (192 aa)
zig-3Protein CBR-ZIG-3. (244 aa)
nsy-4Protein CBR-NSY-4. (302 aa)
clc-2Protein CBR-CLC-2. (254 aa)
cdh-9Protein CBR-CDH-9. (624 aa)
CBG16382Protein CBG16382. (529 aa)
crb-1Protein CBR-CRB-1. (1750 aa)
CBG16014Protein CBG16014. (2753 aa)
him-4Protein CBR-HIM-4. (2899 aa)
unc-71Protein CBR-UNC-71. (1045 aa)
CBG15736Protein CBG15736. (617 aa)
cdh-1Protein CBR-CDH-1. (2212 aa)
zig-12Protein CBG15443. (197 aa)
unc-40Protein CBR-UNC-40. (1407 aa)
unc-97LIM domain-containing protein. (353 aa)
dlg-1Protein CBR-DLG-1; Belongs to the MAGUK family. (1015 aa)
CBG14602Protein CBG14602. (243 aa)
glit-1Protein CBR-GLIT-1. (738 aa)
sax-3Protein CBR-SAX-3. (1295 aa)
clc-3Protein CBR-CLC-3. (222 aa)
jac-1Protein CBR-JAC-1. (1296 aa)
frk-1Tyrosine-protein kinase. (389 aa)
cdh-3Protein CBR-CDH-3. (3207 aa)
cdh-5Protein CBR-CDH-5. (1564 aa)
CBG24230Protein CBG24230. (140 aa)
cdh-12Protein CBR-CDH-12. (2000 aa)
cdh-7Protein CBR-CDH-7. (1397 aa)
rig-3Protein CBR-RIG-3. (531 aa)
bar-1Beta-catenin/armadillo-related protein 1; Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development. Functions as a transcriptional activator but is dependent on the interaction with pop-1. Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses. Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling. Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectoderm [...] (808 aa)
cdh-8Protein CBR-CDH-8. (1784 aa)
Cbr-fmi-1Protein CBR-FMI-1. (2592 aa)
mics-1Protein CBR-MICS-1. (292 aa)
ceh-13Protein CBR-CEH-13. (202 aa)
wrm-1Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa)
let-413Protein CBR-LET-413. (702 aa)
ncam-1Protein CBR-NCAM-1. (965 aa)
CBG25184Protein CBG25184. (1573 aa)
igcm-1Protein CBR-IGCM-1. (1145 aa)
hmr-1Protein CBR-HMR-1; Cadherins are calcium-dependent cell adhesion proteins. (3093 aa)
nlg-1Protein CBR-NLG-1. (800 aa)
syg-2Protein CBR-SYG-2. (1270 aa)
CBG06953Protein CBG06953. (139 aa)
pat-2Integrin alpha pat-2; Required for muscle development probably through the regulation of the actin-myosin cytoskeleton. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52. Required for distal tip cell migration and dorsal pathfinding. Required for egg-laying. May play a role in cell motility and cell-cell interactions. (1224 aa)
ina-1Protein CBR-INA-1; Belongs to the integrin alpha chain family. (1147 aa)
igdb-3Protein CBG05054. (533 aa)
zig-1Protein CBR-ZIG-1. (265 aa)
zig-7Protein CBR-ZIG-7. (181 aa)
casy-1Protein CBR-CASY-1. (983 aa)
vab-23Protein CBR-VAB-23. (260 aa)
CBG11732Protein CBG11732. (875 aa)
CBG29115Protein CBG29115. (733 aa)
CBG24714Protein CBG24714. (40 aa)
vha-12Probable V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Required for necrotic cell death and epidermal cell fusion (By similarity). Belongs to the ATPase alpha/beta chains family. (491 aa)
CBG21718Protein CBG21718. (1544 aa)
zyx-1Protein CBR-ZYX-1. (610 aa)
syg-1Protein CBR-SYG-1. (746 aa)
igcm-3Protein CBR-IGCM-3. (589 aa)
vab-9Protein CBR-VAB-9. (170 aa)
hmp-1Protein CBR-HMP-1. (917 aa)
wrk-1Protein CBR-WRK-1. (576 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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