STRINGSTRING
sol-2 sol-2 CBG20827 CBG20827 trf-1 trf-1 Cbr-try-10 Cbr-try-10 eat-2 eat-2 stg-1 stg-1 trf-2 trf-2 gbb-1 gbb-1 daf-1 daf-1 nmr-1 nmr-1 pat-3 pat-3 CBG04248 CBG04248 CBG04600 CBG04600 ina-1 ina-1 pat-2 pat-2 CBG07404 CBG07404 molo-1 molo-1 daf-4 daf-4 sol-1 sol-1 CBG14815 CBG14815 daf-2 daf-2 gbb-2 gbb-2 CBG01732 CBG01732 CBG01733 CBG01733 Cbr-pat-4 Cbr-pat-4 glr-1 glr-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sol-2Protein CBG19743. (299 aa)
CBG20827Protein CBG20827. (362 aa)
trf-1Protein CBR-TRF-1. (439 aa)
Cbr-try-10Protein CBG29112. (378 aa)
eat-2Neuronal acetylcholine receptor subunit eat-2; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity (By similarity). (481 aa)
stg-1Protein CBR-STG-1. (843 aa)
trf-2Protein CBG23748. (294 aa)
gbb-1Protein CBG02016. (933 aa)
daf-1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (665 aa)
nmr-1Protein CBR-NMR-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1064 aa)
pat-3Integrin beta; Belongs to the integrin beta chain family. (818 aa)
CBG04248Protein CBG04248. (325 aa)
CBG04600Protein CBG04600. (262 aa)
ina-1Protein CBR-INA-1; Belongs to the integrin alpha chain family. (1147 aa)
pat-2Integrin alpha pat-2; Required for muscle development probably through the regulation of the actin-myosin cytoskeleton. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52. Required for distal tip cell migration and dorsal pathfinding. Required for egg-laying. May play a role in cell motility and cell-cell interactions. (1224 aa)
CBG07404Protein CBG07404. (214 aa)
molo-1Protein CBG08983. (289 aa)
daf-4Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (742 aa)
sol-1Protein CBR-SOL-1. (596 aa)
CBG14815Protein CBG14815. (399 aa)
daf-2Protein CBR-DAF-2. (1840 aa)
gbb-2Protein CBG01699; Belongs to the G-protein coupled receptor 3 family. (738 aa)
CBG01732Protein CBG01732. (549 aa)
CBG01733Protein CBG01733. (299 aa)
Cbr-pat-4Protein CBR-PAT-4. (278 aa)
glr-1Protein CBR-GLR-1. (978 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.