(43 nodes) Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG23770	Protein CBG23770. (299 aa)
	CBG24259	Serine/threonine-protein phosphatase. (353 aa)
	CBG24260	Protein CBG24260. (275 aa)
	CBG00341	Protein CBG00341. (291 aa)
	CBG00433	Serine/threonine-protein phosphatase. (372 aa)
	CBG01025	Protein CBG01025. (223 aa)
	CBG03352	Serine/threonine-protein phosphatase. (363 aa)
	CBG04124	Protein CBG04124. (344 aa)
	CBG04555	Protein CBG04555. (269 aa)
	CBG04580	Protein CBG04580. (362 aa)
	let-92	Serine/threonine-protein phosphatase. (318 aa)
	CBG05769	Protein CBG05769. (570 aa)
	CBG08329	Serine/threonine-protein phosphatase. (381 aa)
	tax-6	Serine/threonine-protein phosphatase. (532 aa)
	CBG09147	Serine/threonine-protein phosphatase. (438 aa)
	pph-1	Protein CBR-PPH-1. (272 aa)
	CBG09394	Serine/threonine-protein phosphatase. (313 aa)
	pph-6	Serine/threonine-protein phosphatase. (330 aa)
	CBG09902	Serine/threonine-protein phosphatase. (325 aa)
	CBG11338	Protein CBG11338. (316 aa)
	CBG11669	Protein CBG11669. (119 aa)
	pph-4.1	Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] (333 aa)
	CBG12546	Serine/threonine-protein phosphatase. (353 aa)
	CBG12555	Serine/threonine-protein phosphatase. (389 aa)
	CBG12586	Serine/threonine-protein phosphatase. (368 aa)
	CBG13388	Serine/threonine-protein phosphatase. (358 aa)
	CBG15204	Serine/threonine-protein phosphatase. (369 aa)
	pef-1	Serine/threonine-protein phosphatase with EF-hands. (722 aa)
	CBG18099	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (319 aa)
	CBG18709	Protein CBG18709. (227 aa)
	CBG18710	Serine/threonine-protein phosphatase. (334 aa)
	CBG20366	Serine/threonine-protein phosphatase. (246 aa)
	CBG20474	Serine/threonine-protein phosphatase. (385 aa)
	pph-5	Protein CBR-PPH-5. (496 aa)
	CBG20631	Protein CBG20631. (588 aa)
	Cbr-gsp-4	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (242 aa)
	CBG21717	Protein CBG21717. (344 aa)
	CBG21670	Protein CBG21670. (231 aa)
	CBG22959	Serine/threonine-protein phosphatase. (551 aa)
	CBG22919	Serine/threonine-protein phosphatase. (339 aa)
	CBG08269	Serine/threonine-protein phosphatase. (458 aa)
	gsp-1	Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation (By similarity); Belongs to the PPP phosphatase family. PP-1 subfamily. (329 aa)
	gsp-2	Serine/threonine-protein phosphatase PP1-beta; Serine/threonine-protein phosphatase essential for chromosomal dynamics during meiosis and mitosis. Antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Also involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Essential for embryogenesis (By similarity). (333 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG04124	CBG04555	A8WW96	A8WXX1	Protein CBG04124.	Protein CBG04555.	0.487
CBG04124	CBG11338	A8WW96	A8XD88	Protein CBG04124.	Protein CBG11338.	0.454
CBG04124	CBG21717	A8WW96	A8Y0N1	Protein CBG04124.	Protein CBG21717.	0.490
CBG04555	CBG04124	A8WXX1	A8WW96	Protein CBG04555.	Protein CBG04124.	0.487
CBG04555	CBG11338	A8WXX1	A8XD88	Protein CBG04555.	Protein CBG11338.	0.423
CBG04580	CBG09902	A8WXZ4	A8X9X7	Protein CBG04580.	Serine/threonine-protein phosphatase.	0.475
CBG04580	CBG13388	A8WXZ4	A8XHV8	Protein CBG04580.	Serine/threonine-protein phosphatase.	0.482
CBG04580	CBG18099	A8WXZ4	A8XT11	Protein CBG04580.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.492
CBG04580	CBG18709	A8WXZ4	A8XTY6	Protein CBG04580.	Protein CBG18709.	0.506
CBG04580	CBG20631	A8WXZ4	A8XY91	Protein CBG04580.	Protein CBG20631.	0.451
CBG05769	CBG21717	A8X1P0	A8Y0N1	Protein CBG05769.	Protein CBG21717.	0.489
CBG09902	CBG04580	A8X9X7	A8WXZ4	Serine/threonine-protein phosphatase.	Protein CBG04580.	0.475
CBG09902	CBG13388	A8X9X7	A8XHV8	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase.	0.441
CBG09902	CBG20631	A8X9X7	A8XY91	Serine/threonine-protein phosphatase.	Protein CBG20631.	0.403
CBG11338	CBG04124	A8XD88	A8WW96	Protein CBG11338.	Protein CBG04124.	0.454
CBG11338	CBG04555	A8XD88	A8WXX1	Protein CBG11338.	Protein CBG04555.	0.423
CBG11338	CBG18709	A8XD88	A8XTY6	Protein CBG11338.	Protein CBG18709.	0.410
CBG11338	CBG21717	A8XD88	A8Y0N1	Protein CBG11338.	Protein CBG21717.	0.525
CBG11338	CBG24260	A8XD88	A8WKB8	Protein CBG11338.	Protein CBG24260.	0.445
CBG13388	CBG04580	A8XHV8	A8WXZ4	Serine/threonine-protein phosphatase.	Protein CBG04580.	0.482