STRINGSTRING
smg-1 smg-1 trr-1 trr-1 let-363 let-363 atl-1 atl-1 atm-1 atm-1 CBG25377 CBG25377
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
smg-1Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2 (By similarity); Belongs to the PI3/PI4-kinase family. (2313 aa)
trr-1Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions. Required for spermatogenesis and embryonic development. Acts with tra-2 to promote expression of fog-3 and control male tail development. Involved in the negative regulation of vulval development (By similarity). (4115 aa)
let-363Serine/threonine-protein kinase TOR. (1721 aa)
atl-1Protein CBR-ATL-1; Belongs to the PI3/PI4-kinase family. (2556 aa)
atm-1Protein CBR-ATM-1; Belongs to the PI3/PI4-kinase family. (639 aa)
CBG25377Protein CBG25377; Belongs to the PI3/PI4-kinase family. (916 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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