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CBG00653 CBG00653 pxf-1 pxf-1 CBG05010 CBG05010 egl-2 egl-2 CBG06931 CBG06931 tax-4 tax-4 CBG06970 CBG06970 egl-4 egl-4 epac-1 epac-1 CBG09990 CBG09990 cng-1 cng-1 tax-2 tax-2 CBG00142 CBG00142 hgo-1 hgo-1 CBG13458 CBG13458 kin-2 kin-2 cnnm-2 cnnm-2 pkg-2 pkg-2 cng-2 cng-2 CBG17881 CBG17881 CBG19118 CBG19118 unc-103 unc-103 CBG25106 CBG25106 CBG22517 CBG22517 cdo-1 cdo-1 haao-1 haao-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG00653Protein CBG00653. (1366 aa)
pxf-1Protein CBR-PXF-1. (1469 aa)
CBG05010Protein CBG05010. (190 aa)
egl-2Protein CBR-EGL-2. (950 aa)
CBG06931Protein CBG06931. (1334 aa)
tax-4Protein CBR-TAX-4. (726 aa)
CBG069701,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog 2; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene); Belongs to the acireductone dioxygenase (ARD) family. (159 aa)
egl-4cGMP-dependent protein kinase egl-4; Promotes chemoreceptor gene expression in response to increased cGMP levels by antagonizing the gene repression functions of the class II HDAC hda-4 and the mef-2 transcription factor. Regulates gene expression via recruitment of a histone deacetylase complex containing hda-2, saeg-1 and saeg-2. Represses body size and lifespan through the dbl-1 and insulin pathways, respectively. May also signal through daf-3 and/or daf-5. Role in egg-laying, dauer formation and motility. Regulates behavioral responses to various chemosensory stimuli in sensory neu [...] (749 aa)
epac-1Protein CBR-EPAC-1. (1101 aa)
CBG09990Mannose-6-phosphate isomerase. (409 aa)
cng-1Protein CBR-CNG-1. (682 aa)
tax-2Protein CBR-TAX-2. (810 aa)
CBG001421,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (178 aa)
hgo-1Protein CBR-HGO-1. (445 aa)
CBG134581,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog 3; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene); Belongs to the acireductone dioxygenase (ARD) family. (158 aa)
kin-2Protein CBR-KIN-2. (366 aa)
cnnm-2Protein CBG15463. (773 aa)
pkg-2Protein CBR-PKG-2. (616 aa)
cng-2Protein CBG16807. (814 aa)
CBG17881Protein CBG17881. (235 aa)
CBG19118Protein CBG19118. (468 aa)
unc-103Protein CBR-UNC-103.2. (801 aa)
CBG25106Protein CBG25106. (639 aa)
CBG22517Protein CBG22517. (661 aa)
cdo-1Cysteine dioxygenase; Belongs to the cysteine dioxygenase family. (190 aa)
haao-13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (281 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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