STRINGSTRING
pms-2 pms-2 CBG25497 CBG25497 xol-1 xol-1 daf-21 daf-21 crn-5 crn-5 gfm-1 gfm-1 top-2 top-2 CBG03843 CBG03843 exos-7 exos-7 arx-4 arx-4 CBG24397 CBG24397 hsp-75 hsp-75 exos-4.1 exos-4.1 enpl-1 enpl-1 impt-1 impt-1 eftu-2 eftu-2 exos-8 exos-8 CBG11440 CBG11440 rps-16 rps-16 lonp-1 lonp-1 CBG15144 CBG15144 CBG15142 CBG15142 mlh-1 mlh-1 mrps-9 mrps-9 exos-9 exos-9 eef-2 eef-2 rps-2 rps-2 CBG18156 CBG18156 CBG20661 CBG20661 mvk-1 mvk-1 Cbr-tag-96 Cbr-tag-96 lonp-2 lonp-2 mrps-5 mrps-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pms-2Protein CBR-PMS-2. (838 aa)
CBG25497Protein CBG25497. (841 aa)
xol-1XO lethal protein 1 homolog; Belongs to the GHMP kinase family. Xol-1 subfamily. (426 aa)
daf-21Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] (706 aa)
crn-5Protein CBR-CRN-5. (214 aa)
gfm-1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (724 aa)
top-2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1482 aa)
CBG03843Protein CBG03843. (909 aa)
exos-7Protein CBR-EXOS-7. (307 aa)
arx-4Protein CBR-ARX-4. (539 aa)
CBG24397Protein CBG24397. (193 aa)
hsp-75Protein CBG00585. (672 aa)
exos-4.1Putative exosome complex component RRP41; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. (240 aa)
enpl-1Protein CBG06014. (776 aa)
impt-1Protein CBG08009. (258 aa)
eftu-2Protein CBR-EFTU-2. (990 aa)
exos-8Protein CBR-EXOS-8. (361 aa)
CBG11440Protein CBG11440. (868 aa)
rps-16Protein CBR-RPS-16; Belongs to the universal ribosomal protein uS9 family. (144 aa)
lonp-1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (960 aa)
CBG15144Protein CBG15144. (729 aa)
CBG15142Protein CBG15142. (802 aa)
mlh-1Protein CBR-MLH-1. (761 aa)
mrps-9Protein CBR-MRPS-9. (392 aa)
exos-9Protein CBR-EXOS-9. (434 aa)
eef-2Protein CBR-EFT-2. (862 aa)
rps-2Protein CBR-RPS-2. (85 aa)
CBG18156DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1207 aa)
CBG20661Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (372 aa)
mvk-1Protein CBR-MVK-1. (715 aa)
Cbr-tag-96Protein CBR-TAG-96. (423 aa)
lonp-2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. (773 aa)
mrps-5Putative 28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family. (415 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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