(20 nodes) Voltage-dependent channel domain superfamily network (Caenorhabditis briggsae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	kvs-3	Protein CBR-KVS-3; Belongs to the potassium channel family. (443 aa)
	kqt-2	Protein CBR-KQT-2; Belongs to the potassium channel family. (638 aa)
	CBG26471	Protein CBG26471. (100 aa)
	CBG22329	Protein CBG22329. (208 aa)
	shw-1	Protein CBR-SHW-1; Belongs to the potassium channel family. (775 aa)
	shk-1	Protein CBG01037; Belongs to the potassium channel family. (490 aa)
	unc-2	Protein CBR-UNC-2. (1536 aa)
	shl-1	Protein CBG05460; Belongs to the potassium channel family. (596 aa)
	unc-77	Protein CBR-NCA-1. (1883 aa)
	egl-19	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1780 aa)
	kvs-2	Protein CBG09661; Belongs to the potassium channel family. (589 aa)
	shw-3	Protein CBR-SHW-3; Belongs to the potassium channel family. (479 aa)
	exp-2	Protein CBR-EXP-2; Belongs to the potassium channel family. (531 aa)
	kvs-5	Protein CBR-KVS-5; Belongs to the potassium channel family. (508 aa)
	kqt-1	Protein CBR-KQT-1; Belongs to the potassium channel family. (824 aa)
	slo-1	Protein CBR-SLO-1. (1165 aa)
	kvs-1	Protein CBR-KVS-1; Belongs to the potassium channel family. (472 aa)
	cca-1	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1921 aa)
	nca-2	Protein CBR-NCA-2. (1809 aa)
	kvs-4	Protein CBR-KVS-4; Belongs to the potassium channel family. (497 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cca-1	egl-19	A8XPX1	A8X1H0	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.781
cca-1	exp-2	A8XPX1	A8X9J4	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-EXP-2; Belongs to the potassium channel family.	0.657
cca-1	kvs-1	A8XPX1	A8XPS0	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-KVS-1; Belongs to the potassium channel family.	0.533
cca-1	nca-2	A8XPX1	A8XS56	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-NCA-2.	0.729
cca-1	shk-1	A8XPX1	A8WP18	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBG01037; Belongs to the potassium channel family.	0.643
cca-1	slo-1	A8XPX1	A8XGP3	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-SLO-1.	0.403
cca-1	unc-2	A8XPX1	A8WRW6	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-UNC-2.	0.761
cca-1	unc-77	A8XPX1	A8X017	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	Protein CBR-NCA-1.	0.612
egl-19	cca-1	A8X1H0	A8XPX1	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.781
egl-19	exp-2	A8X1H0	A8X9J4	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Protein CBR-EXP-2; Belongs to the potassium channel family.	0.654
egl-19	shk-1	A8X1H0	A8WP18	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Protein CBG01037; Belongs to the potassium channel family.	0.775
egl-19	slo-1	A8X1H0	A8XGP3	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Protein CBR-SLO-1.	0.842
egl-19	unc-2	A8X1H0	A8WRW6	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	Protein CBR-UNC-2.	0.662
exp-2	cca-1	A8X9J4	A8XPX1	Protein CBR-EXP-2; Belongs to the potassium channel family.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.657
exp-2	egl-19	A8X9J4	A8X1H0	Protein CBR-EXP-2; Belongs to the potassium channel family.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.654
exp-2	kqt-2	A8X9J4	A8Y310	Protein CBR-EXP-2; Belongs to the potassium channel family.	Protein CBR-KQT-2; Belongs to the potassium channel family.	0.513
exp-2	unc-2	A8X9J4	A8WRW6	Protein CBR-EXP-2; Belongs to the potassium channel family.	Protein CBR-UNC-2.	0.405
kqt-1	shk-1	A8XC51	A8WP18	Protein CBR-KQT-1; Belongs to the potassium channel family.	Protein CBG01037; Belongs to the potassium channel family.	0.423
kqt-1	shl-1	A8XC51	A8WZX5	Protein CBR-KQT-1; Belongs to the potassium channel family.	Protein CBG05460; Belongs to the potassium channel family.	0.400
kqt-2	exp-2	A8Y310	A8X9J4	Protein CBR-KQT-2; Belongs to the potassium channel family.	Protein CBR-EXP-2; Belongs to the potassium channel family.	0.513