STRINGSTRING
rgs-1 rgs-1 CBG20722 CBG20722 Cbr-rgs-4 Cbr-rgs-4 axl-1 axl-1 rgs-7 rgs-7 rgs-6 rgs-6 grk-2 grk-2 rgs-2 rgs-2 pry-1 pry-1 grk-1 grk-1 CBG25672 CBG25672 egl-10 egl-10 snx-14 snx-14 CBG20725 CBG20725 CBG20723 CBG20723 CBG20724 CBG20724 snx-13 snx-13 rgs-3 rgs-3 eat-16 eat-16 rhgf-1 rhgf-1 rgs-5 rgs-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rgs-1Protein CBR-RGS-1. (215 aa)
CBG20722Protein CBG20722. (176 aa)
Cbr-rgs-4Protein CBR-RGS-4. (191 aa)
axl-1Axin-like protein 1; Works in parallel with pry-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Shown to have a role in excretory cell development (By similarity). (395 aa)
rgs-7Protein CBR-RGS-7. (892 aa)
rgs-6Protein CBR-RGS-6. (750 aa)
grk-2Protein CBR-GRK-2. (377 aa)
rgs-2Protein CBR-RGS-2. (174 aa)
pry-1Axin-like protein pry-1; Works in parallel with axl-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Inhibits Wnt signaling, which affects tissue specific expression of Hox genes, egl- 5, lin-39 and mab-5. This in turn affects QR (postembryonic neuroblast) cell migration, vulval cell fate specification, and the development of sensory structures by the seam cell lineage. Has a role in alae V cell patterning, ray formation in the male tail and axon guidance. Does not affect B cell polarity (By similarity). (625 aa)
grk-1G protein-coupled receptor kinase 1; Specifically phosphorylates the activated forms of G protein- coupled receptors; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (640 aa)
CBG25672Protein CBG25672. (72 aa)
egl-10Protein CBR-EGL-10. (549 aa)
snx-14Protein CBG20763. (979 aa)
CBG20725Protein CBG20725. (188 aa)
CBG20723Protein CBG20723. (160 aa)
CBG20724Protein CBG20724. (162 aa)
snx-13Protein CBG00428. (962 aa)
rgs-3Protein CBR-RGS-3. (364 aa)
eat-16Protein CBR-EAT-16. (485 aa)
rhgf-1Protein CBR-RHGF-1. (1376 aa)
rgs-5Protein CBR-RGS-5. (486 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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