STRINGSTRING
CBG04113 CBG04113 cye-1 cye-1 cyd-1 cyd-1 cic-1 cic-1 cyl-1 cyl-1 cit-1.2 cit-1.2 cit-1.1 cit-1.1 CBG22965 CBG22965 CBG20098 CBG20098 CBG19101 CBG19101 cyy-1 cyy-1 cdka-1 cdka-1 cyh-1 cyh-1 cyb-1 cyb-1 CBG17731 CBG17731 CBG15501 CBG15501 brf-1 brf-1 cya-1 cya-1 ttb-1 ttb-1 cyb-3 cyb-3 CBG05210 CBG05210 ccnk-1 ccnk-1 lin-35 lin-35
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG04113Protein CBG04113. (775 aa)
cye-1G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] (518 aa)
cyd-1Protein CBR-CYD-1; Belongs to the cyclin family. (427 aa)
cic-1Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase cdk-8 that phosphoryl [...] (298 aa)
cyl-1Protein CBR-CYL-1; Belongs to the cyclin family. (209 aa)
cit-1.2Protein CBR-CIT-1.2. (792 aa)
cit-1.1Protein CBR-CIT-1.1. (161 aa)
CBG22965Protein CBG22965. (281 aa)
CBG20098Protein CBG20098; Belongs to the cyclin family. (397 aa)
CBG19101Protein CBG19101. (318 aa)
cyy-1Protein CBR-CYY-1; Belongs to the cyclin family. (357 aa)
cdka-1Cyclin-dependent kinase 5 activator. (366 aa)
cyh-1Protein CBR-CYH-1. (320 aa)
cyb-1Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa)
CBG17731Protein CBG17731. (339 aa)
CBG15501Protein CBG15501. (583 aa)
brf-1Protein CBR-BRF-1. (781 aa)
cya-1Protein CBG06936; Belongs to the cyclin family. (467 aa)
ttb-1Protein CBR-TTB-1. (306 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
CBG05210Protein CBG05210; Belongs to the cyclin family. (290 aa)
ccnk-1Protein CBG04574; Belongs to the cyclin family. (260 aa)
lin-35Protein CBR-LIN-35. (956 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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