STRINGSTRING
CBG20887 CBG20887 CBG04553 CBG04553 egl-8 egl-8 ckk-1 ckk-1 acy-3 acy-3 acy-4 acy-4 acy-2 acy-2 CBG13912 CBG13912 CBG14305 CBG14305 kin-2 kin-2 acy-1 acy-1 sel-2 sel-2 zyg-8 zyg-8 plc-2 plc-2 CBG19820 CBG19820 kin-1 kin-1 pde-1 pde-1 pde-3 pde-3 egl-30 egl-30 CBG25427 CBG25427
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG20887Protein CBG20887. (209 aa)
CBG04553Protein CBG04553. (1075 aa)
egl-8Phosphoinositide phospholipase C. (1528 aa)
ckk-1Protein CBR-CKK-1. (538 aa)
acy-3Protein CBR-ACY-3. (1243 aa)
acy-4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1000 aa)
acy-2Protein CBR-ACY-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1132 aa)
CBG13912Protein CBG13912. (271 aa)
CBG14305cAMP-dependent protein kinase, catalytic subunit-like. (385 aa)
kin-2Protein CBR-KIN-2. (366 aa)
acy-1Protein CBR-ACY-1. (1287 aa)
sel-2Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells (By similarity). (2531 aa)
zyg-8Protein CBR-ZYG-8. (822 aa)
plc-2Phosphoinositide phospholipase C. (933 aa)
CBG19820Protein CBG19820. (173 aa)
kin-1cAMP-dependent protein kinase catalytic subunit; Essential for larval development. Controls the rhythmic contraction of enteric muscles probably by regulating G-protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons. Plays a role in the control of oocyte meiotic maturation by gonadal sheath cells. May play a role in the regulation of neuromuscular junctions. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. cAMP subfamily. (374 aa)
pde-1Phosphodiesterase. (662 aa)
pde-3Phosphodiesterase. (504 aa)
egl-30Protein CBR-EGL-30. (388 aa)
CBG25427Protein CBG25427. (69 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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