STRINGSTRING
tbx-9 tbx-9 alp-1 alp-1 arx-4 arx-4 CBG24079 CBG24079 Cbr-tbx-11 Cbr-tbx-11 sea-1.3 sea-1.3 hmbx-1 hmbx-1 gap-3 gap-3 hlh-2 hlh-2 ceh-49.3 ceh-49.3 ceh-49.2 ceh-49.2 ceh-49.6 ceh-49.6 ceh-49.8 ceh-49.8 aph-2 aph-2 cdk-5 cdk-5 mpk-1 mpk-1 mapk-15 mapk-15 cog-1 cog-1 tbx-37 tbx-37 clic-1 clic-1 unc-5 unc-5 ceh-49.7 ceh-49.7 smp-1 smp-1 hmp-2 hmp-2 CBG19500 CBG19500 CBG19497 CBG19497 CBG19489 CBG19489 CBG19488 CBG19488 CBG19473 CBG19473 lipl-2 lipl-2 drap-1 drap-1 swt-5 swt-5 odr-2 odr-2 unc-70 unc-70 egl-46 egl-46 lipl-4 lipl-4 CBG18431 CBG18431 arx-3 arx-3 cdka-1 cdka-1 arx-6 arx-6 cnt-2 cnt-2 zig-5 zig-5 ntl-9 ntl-9 dgn-1 dgn-1 CBG17392 CBG17392 CBG17314 CBG17314 CBG17250 CBG17250 CBG17261 CBG17261 sem-5 sem-5 zig-3 zig-3 zig-4 zig-4 viro-2 viro-2 ceh-20 ceh-20 gei-8 gei-8 apa-2 apa-2 dgn-2 dgn-2 CBG16014 CBG16014 him-4 him-4 arx-5 arx-5 ral-1 ral-1 CBG15514 CBG15514 tbx-43 tbx-43 CBG15067 CBG15067 ceh-49.1 ceh-49.1 ceh-49.5 ceh-49.5 CBG15045 CBG15045 unc-33 unc-33 cdap-2 cdap-2 unc-40 unc-40 CBG14863 CBG14863 pak-1 pak-1 aps-2 aps-2 dpy-23 dpy-23 nck-1 nck-1 sax-3 sax-3 CBG14206 CBG14206 spc-1 spc-1 ngn-1 ngn-1 CBG13916 CBG13916 plx-1 plx-1 CBG13865 CBG13865 CBG13862 CBG13862 CBG13699 CBG13699 CBG13668 CBG13668 rho-1 rho-1 CBG13434 CBG13434 vab-1 vab-1 pen-2 pen-2 tbx-38 tbx-38 CBG12765 CBG12765 let-381 let-381 ceh-6 ceh-6 CBG12470 CBG12470 mef-2 mef-2 hop-1 hop-1 CBG12078 CBG12078 unc-73 unc-73 smp-2 smp-2 CBG11796 CBG11796 sea-1.4 sea-1.4 sea-1.2 sea-1.2 spe-48 spe-48 ceh-38 ceh-38 unc-6 unc-6 ceh-60 ceh-60 ets-4 ets-4 bar-1 bar-1 aap-1 aap-1 CBG10797 CBG10797 vab-2 vab-2 CBG10702 CBG10702 lipl-3 lipl-3 unc-16 unc-16 ceh-44 ceh-44 chc-1 chc-1 unc-44.1 unc-44.1 unc-44.2 unc-44.2 lipl-1 lipl-1 akt-1 akt-1 ceh-22 ceh-22 ceh-13 ceh-13 CBG08958 CBG08958 CBG09014 CBG09014 tbx-7 tbx-7 ubq-1 ubq-1 mig-21 mig-21 sma-4 sma-4 soc-1 soc-1 ceh-45 ceh-45 rskn-2 rskn-2 daf-3 daf-3 CBG08105 CBG08105 sel-12 sel-12 gsk-3 gsk-3 CBG07897 CBG07897 CBG07284 CBG07284 efn-3 efn-3 CBG07560 CBG07560 slt-1 slt-1 unc-3 unc-3 CBG07744 CBG07744 unc-60 unc-60 CBG06508 CBG06508 CBG06505 CBG06505 ceh-48 ceh-48 let-60 let-60 pha-4 pha-4 CBG05575 CBG05575 ceh-40 ceh-40 CBG05212 CBG05212 shc-1 shc-1 hot-1 hot-1 lipl-8 lipl-8 sdn-1 sdn-1 abl-1 abl-1 tbx-11 tbx-11 efn-2 efn-2 ebax-1 ebax-1 CBG04338 CBG04338 CBG04336 CBG04336 zig-1 zig-1 CBG04202 CBG04202 arx-7 arx-7 mek-2 mek-2 CBG04106 CBG04106 lim-7 lim-7 CBG03641 CBG03641 CBG03490 CBG03490 lipl-7 lipl-7 lin-22 lin-22 lad-2 lad-2 mpk-2 mpk-2 CBG02328 CBG02328 nmr-1 nmr-1 zig-10 zig-10 max-2 max-2 Cbr-max-2 Cbr-max-2 pmk-3 pmk-3 pmk-2 pmk-2 pmk-1 pmk-1 wsp-1 wsp-1 CBG01565 CBG01565 lipl-5 lipl-5 CBG01147 CBG01147 CBG01035 CBG01035 vab-9 vab-9 itsn-1 itsn-1 sea-1.1 sea-1.1 ttx-3 ttx-3 CBG00206 CBG00206 CBG00197 CBG00197 tbx-8 tbx-8 CBG00135 CBG00135 mdt-22 mdt-22 plx-2 plx-2 efn-4 efn-4 dhp-2 dhp-2 arx-1 arx-1 daf-21 daf-21 arx-2 arx-2 mdt-18 mdt-18 mdt-21 mdt-21 mdt-11 mdt-11 dhp-1 dhp-1 mab-20 mab-20 hlh-1 hlh-1 age-1 age-1 Cbr-sax-7 Cbr-sax-7 spe-4 spe-4 mdt-26 mdt-26 CBG16668 CBG16668 CBG02851 CBG02851 CBG25184 CBG25184 CBG26166 CBG26166 CBG26082 CBG26082 CBG25355 CBG25355 ceh-23 ceh-23 CBG27575 CBG27575 CBG25604 CBG25604 CBG21718 CBG21718 aph-1 aph-1 hmp-1 hmp-1 bus-18 bus-18 sma-1 sma-1 CBG23363 CBG23363 tln-1 tln-1 drag-1 drag-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tbx-9Protein CBR-TBX-9. (317 aa)
alp-1Protein CBR-ALP-1. (2170 aa)
arx-4Protein CBR-ARX-4. (539 aa)
CBG24079Protein CBG24079. (90 aa)
Cbr-tbx-11Protein CBR-TBX-11. (350 aa)
sea-1.3Protein CBG11640. (526 aa)
hmbx-1Protein CBR-HMBX-1. (422 aa)
gap-3Protein CBG22075. (960 aa)
hlh-2Protein CBR-HLH-2. (426 aa)
ceh-49.3Protein CBG21593. (240 aa)
ceh-49.2Protein CBG21591. (189 aa)
ceh-49.6One cut domain family member. (292 aa)
ceh-49.8Protein CBG21587. (203 aa)
aph-2Protein CBR-APH-2. (721 aa)
cdk-5Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa)
mpk-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
mapk-15Mitogen-activated protein kinase. (458 aa)
cog-1Protein CBR-COG-1. (261 aa)
tbx-37Protein CBG20877. (294 aa)
clic-1Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa)
unc-5Protein CBR-UNC-5. (922 aa)
ceh-49.7One cut domain family member. (350 aa)
smp-1Protein CBR-SMP-1; Belongs to the semaphorin family. (714 aa)
hmp-2Protein CBR-HMP-2. (686 aa)
CBG19500One cut domain family member. (168 aa)
CBG19497Protein CBG19497. (91 aa)
CBG19489DNA-binding protein SATB. (735 aa)
CBG19488DNA-binding protein SATB. (701 aa)
CBG19473Protein CBG19473. (96 aa)
lipl-2Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (382 aa)
drap-1Protein CBR-DRAP-1. (301 aa)
swt-5Sugar transporter SWEET; Mediates sugar transport across membranes. Belongs to the SWEET sugar transporter family. (238 aa)
odr-2Protein CBR-ODR-2. (173 aa)
unc-70Spectrin beta chain; Belongs to the spectrin family. (2370 aa)
egl-46Protein CBR-EGL-46. (283 aa)
lipl-4Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (423 aa)
CBG18431Protein CBG18431. (188 aa)
arx-3Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (382 aa)
cdka-1Cyclin-dependent kinase 5 activator. (366 aa)
arx-6Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
cnt-2Protein CBR-CNT-2. (1161 aa)
zig-5Protein CBR-ZIG-5. (255 aa)
ntl-9Protein CBR-NTL-9. (314 aa)
dgn-1Protein CBR-DGN-1. (594 aa)
CBG17392Protein CBG17392. (1745 aa)
CBG17314Protein CBG17314. (1151 aa)
CBG17250Protein CBG17250. (212 aa)
CBG17261Protein CBG17261. (312 aa)
sem-5Protein CBR-SEM-5. (229 aa)
zig-3Protein CBR-ZIG-3. (244 aa)
zig-4Protein CBR-ZIG-4. (250 aa)
viro-2Protein CBG16600. (552 aa)
ceh-20Protein CBR-CEH-20. (338 aa)
gei-8Protein CBR-GEI-8. (1819 aa)
apa-2AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (925 aa)
dgn-2Protein CBR-DGN-2. (395 aa)
CBG16014Protein CBG16014. (2753 aa)
him-4Protein CBR-HIM-4. (2899 aa)
arx-5Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
ral-1Protein CBR-RAL-1. (213 aa)
CBG15514Protein CBG15514. (232 aa)
tbx-43Protein CBR-TBX-43. (301 aa)
CBG15067Protein CBG15067. (253 aa)
ceh-49.1One cut domain family member. (351 aa)
ceh-49.5One cut domain family member. (351 aa)
CBG15045Protein CBG15045. (111 aa)
unc-33Protein CBR-UNC-33. (862 aa)
cdap-2Protein CBG14969. (544 aa)
unc-40Protein CBR-UNC-40. (1407 aa)
CBG14863Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
pak-1Non-specific serine/threonine protein kinase. (626 aa)
aps-2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
dpy-23Protein CBR-DPY-23; Belongs to the adaptor complexes medium subunit family. (435 aa)
nck-1Protein CBR-NCK-1. (393 aa)
sax-3Protein CBR-SAX-3. (1295 aa)
CBG14206Protein CBG14206. (297 aa)
spc-1Protein CBR-SPC-1. (2467 aa)
ngn-1Protein CBR-NGN-1. (200 aa)
CBG13916Protein CBG13916. (1173 aa)
plx-1Protein CBR-PLX-1. (1959 aa)
CBG13865One cut domain family member. (538 aa)
CBG13862Homeobox protein cut-like. (827 aa)
CBG13699Protein CBG13699. (277 aa)
CBG13668One cut domain family member. (688 aa)
rho-1Protein CBR-RHO-1. (192 aa)
CBG13434Protein CBG13434. (191 aa)
vab-1Protein CBR-VAB-1. (1118 aa)
pen-2Protein CBR-PEN-2. (101 aa)
tbx-38Protein CBR-TBX-37. (308 aa)
CBG12765Protein CBG12765. (713 aa)
let-381Protein CBR-LET-381. (363 aa)
ceh-6POU domain protein. (569 aa)
CBG12470Protein CBG12470. (171 aa)
mef-2Protein CBR-MEF-2. (343 aa)
hop-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
CBG12078Protein CBG12078. (812 aa)
unc-73Protein CBR-UNC-73. (1618 aa)
smp-2Protein CBR-SMP-2; Belongs to the semaphorin family. (689 aa)
CBG11796One cut domain family member. (419 aa)
sea-1.4Protein CBG11646. (438 aa)
sea-1.2Protein CBR-SEA-1. (566 aa)
spe-48Protein CBG22135. (329 aa)
ceh-38One cut domain family member. (626 aa)
unc-6Protein CBR-UNC-6. (621 aa)
ceh-60Protein CBR-CEH-60. (386 aa)
ets-4Protein CBR-ETS-4. (450 aa)
bar-1Beta-catenin/armadillo-related protein 1; Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development. Functions as a transcriptional activator but is dependent on the interaction with pop-1. Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses. Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling. Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectoderm [...] (808 aa)
aap-1Protein CBR-AAP-1. (522 aa)
CBG10797Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (215 aa)
vab-2Protein CBR-VAB-2; Belongs to the ephrin family. (242 aa)
CBG10702One cut domain family member. (419 aa)
lipl-3Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (407 aa)
unc-16Protein CBR-UNC-16. (1158 aa)
ceh-44Homeobox protein cut-like. (1537 aa)
chc-1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1660 aa)
unc-44.1Protein CBG09456. (1857 aa)
unc-44.2Protein CBG09473. (5237 aa)
lipl-1Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (405 aa)
akt-1Non-specific serine/threonine protein kinase. (605 aa)
ceh-22Protein CBR-CEH-22. (356 aa)
ceh-13Protein CBR-CEH-13. (202 aa)
CBG08958Protein CBG08958. (357 aa)
CBG09014Protein CBG09014. (305 aa)
tbx-7Protein CBR-TBX-7. (289 aa)
ubq-1Protein CBR-UBQ-1. (770 aa)
mig-21Protein CBR-MIG-21. (297 aa)
sma-4Dwarfin sma. (603 aa)
soc-1Protein CBR-SOC-1. (510 aa)
ceh-45Protein CBR-CEH-45. (232 aa)
rskn-2Ribosomal protein S6 kinase. (772 aa)
daf-3Dwarfin sma. (1043 aa)
CBG08105Protein CBG08105. (210 aa)
sel-12Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
gsk-3Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa)
CBG07897One cut domain family member. (483 aa)
CBG07284Protein CBG07284. (251 aa)
efn-3Protein CBR-EFN-3; Belongs to the ephrin family. (200 aa)
CBG07560Protein CBG07560; Belongs to the protein kinase superfamily. (367 aa)
slt-1Protein CBR-SLT-1. (1376 aa)
unc-3Protein CBR-UNC-3. (491 aa)
CBG07744Protein CBG07744. (308 aa)
unc-60Protein CBR-UNC-60; Belongs to the actin-binding proteins ADF family. (293 aa)
CBG06508Protein CBG06508. (525 aa)
CBG06505Protein CBG06505. (671 aa)
ceh-48One cut domain family member. (481 aa)
let-60Protein CBR-LET-60. (184 aa)
pha-4Protein CBR-PHA-4. (477 aa)
CBG05575Protein CBG05575. (166 aa)
ceh-40Protein CBG05292. (312 aa)
CBG05212Protein CBG05212. (352 aa)
shc-1Protein CBR-SHC-1. (317 aa)
hot-1Protein CBR-HOT-1. (190 aa)
lipl-8Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
sdn-1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (298 aa)
abl-1Tyrosine-protein kinase. (1211 aa)
tbx-11Protein CBG04534. (348 aa)
efn-2Protein CBR-EFN-2; Belongs to the ephrin family. (219 aa)
ebax-1Protein CBR-PQN-55. (1703 aa)
CBG04338Protein CBG04338. (312 aa)
CBG04336Protein CBG04336. (614 aa)
zig-1Protein CBR-ZIG-1. (265 aa)
CBG04202Protein CBG04202. (675 aa)
arx-7Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (152 aa)
mek-2Protein CBR-MEK-2; Belongs to the protein kinase superfamily. (387 aa)
CBG04106Protein CBG04106. (812 aa)
lim-7Protein CBR-LIM-7. (458 aa)
CBG03641Protein CBG03641. (153 aa)
CBG03490Protein CBG03490. (158 aa)
lipl-7Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (408 aa)
lin-22Protein CBR-LIN-22. (164 aa)
lad-2Protein CBR-LAD-2. (1216 aa)
mpk-2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (573 aa)
CBG02328Protein CBG02328. (438 aa)
nmr-1Protein CBR-NMR-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1064 aa)
zig-10Protein CBG02647. (320 aa)
max-2Protein CBG02801. (317 aa)
Cbr-max-2Protein CBR-MAX-2; Belongs to the protein kinase superfamily. (422 aa)
pmk-3Mitogen-activated protein kinase. (466 aa)
pmk-2Mitogen-activated protein kinase. (392 aa)
pmk-1Mitogen-activated protein kinase. (377 aa)
wsp-1Protein CBR-WSP-1. (785 aa)
CBG01565Protein CBG01565. (188 aa)
lipl-5Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (404 aa)
CBG01147Protein CBG01147. (320 aa)
CBG01035Protein CBG01035. (422 aa)
vab-9Protein CBR-VAB-9. (170 aa)
itsn-1Protein CBR-ITSN-1. (1099 aa)
sea-1.1Protein CBG00340. (614 aa)
ttx-3Protein CBR-TTX-3. (380 aa)
CBG00206Protein CBG00206; Belongs to the protein kinase superfamily. (350 aa)
CBG00197Protein CBG00197. (258 aa)
tbx-8Protein CBR-TBX-8. (308 aa)
CBG00135Probable calcium-binding mitochondrial carrier CBG00135; Calcium-dependent mitochondrial solute carrier. Belongs to the mitochondrial carrier (TC 2.A.29) family. (532 aa)
mdt-22Mediator of RNA polymerase II transcription subunit 22; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (153 aa)
plx-2Plexin-2; Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis. (1773 aa)
efn-4Ephrin-4; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, involved in ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays. Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis; Belongs to the ephrin family. (354 aa)
dhp-2Dihydropyrimidinase 2; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (518 aa)
arx-1Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (426 aa)
daf-21Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] (706 aa)
arx-2Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (393 aa)
mdt-18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (227 aa)
mdt-21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (130 aa)
mdt-11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (193 aa)
dhp-1Dihydropyrimidinase 1. (489 aa)
mab-20Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (656 aa)
hlh-1Myoblast determination protein 1 homolog; Accumulation defines the body wall muscle cell fate during embryogenesis. (329 aa)
age-1Phosphatidylinositol 3-kinase age-1; Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the [...] (1159 aa)
Cbr-sax-7Protein CBR-SAX-7. (1402 aa)
spe-4Protein CBR-SPE-4. (483 aa)
mdt-26Protein CBG02468. (546 aa)
CBG16668Protein CBG16668. (2334 aa)
CBG02851Protein CBG02851. (560 aa)
CBG25184Protein CBG25184. (1573 aa)
CBG26166One cut domain family member. (531 aa)
CBG26082Protein CBG26082. (345 aa)
CBG25355Protein CBG25355. (201 aa)
ceh-23Protein CBG26055. (300 aa)
CBG27575Protein CBG27575. (40 aa)
CBG25604Protein CBG25604. (262 aa)
CBG21718Protein CBG21718. (1544 aa)
aph-1Protein CBR-APH-1. (330 aa)
hmp-1Protein CBR-HMP-1. (917 aa)
bus-18Protein CBR-BUS-18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (834 aa)
sma-1Protein CBR-SMA-1. (4156 aa)
CBG23363Protein CBG23363. (206 aa)
tln-1Protein CBG22153. (1036 aa)
drag-1Protein CBR-DRAG-1. (414 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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