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CBG09880 CBG09880 CBG09850 CBG09850 CBG09820 CBG09820 cox-6b cox-6b CBG09291 CBG09291 fum-1 fum-1 CBG09051 CBG09051 CBG09080 CBG09080 CBG09091 CBG09091 atp-1 atp-1 CBG02478 CBG02478 cyc-2.2 cyc-2.2 sco-1 sco-1 idhg-2 idhg-2 CBG03983 CBG03983 nduf-5 nduf-5 cox-5b cox-5b cox-7c cox-7c dlat-1 dlat-1 CBG05318 CBG05318 CBG06101 CBG06101 CBG06063 CBG06063 nuaf-3 nuaf-3 CBG06643 CBG06643 nuo-5 nuo-5 CBG06846 CBG06846 pdhk-2 pdhk-2 gas-1 gas-1 ucr-2.2 ucr-2.2 sucl-1 sucl-1 cyc-1 cyc-1 cox-18 cox-18 atp6 atp6 nd1 nd1 cox-2 cox-2 ctb-1 ctb-1 ogdh-1 ogdh-1 cts-1 cts-1 nuaf-1 nuaf-1 mev-1 mev-1 CBG29118 CBG29118 dlst-1 dlst-1 CBG26557 CBG26557 men-1 men-1 CBG27170 CBG27170 CBG28046 CBG28046 CBG26013 CBG26013 CBG25625 CBG25625 atp-5 atp-5 CBG23452 CBG23452 aco-2 aco-2 cox-6a cox-6a sdha-1 sdha-1 CBG22500 CBG22500 sft-1 sft-1 lin-66 lin-66 hpo-18 hpo-18 dld-1 dld-1 nuo-3 nuo-3 coa-6 coa-6 CBG21200 CBG21200 atp-2 atp-2 pdhb-1 pdhb-1 CBG21025 CBG21025 CBG20910 CBG20910 CBG20848 CBG20848 CBG20773 CBG20773 CBG20772 CBG20772 CBG20679 CBG20679 CBG02642 CBG02642 CBG02643 CBG02643 hphd-1 hphd-1 CBG02865 CBG02865 CBG02872 CBG02872 ooc-3 ooc-3 nuo-1 nuo-1 sdhd-1 sdhd-1 ldh-1 ldh-1 CBG03221 CBG03221 CBG02223 CBG02223 CBG01548 CBG01548 isp-1 isp-1 cyc-2.1 cyc-2.1 CBG01746 CBG01746 cox-11 cox-11 sdhb-1 sdhb-1 Cbr-sdhb-1 Cbr-sdhb-1 CBG01005 CBG01005 hsp-75 hsp-75 sucg-1 sucg-1 CBG00422 CBG00422 dlat-2 dlat-2 CBG00301 CBG00301 lsy-22 lsy-22 gst-42 gst-42 CBG24506 CBG24506 CBG24154 CBG24154 pdp-1.1 pdp-1.1 lpd-5 lpd-5 CBG23568 CBG23568 nduf-6 nduf-6 CBG20309 CBG20309 nduf-9 nduf-9 CBG20227 CBG20227 CBG20020 CBG20020 cox-4 cox-4 CBG19690 CBG19690 nduf-2.2 nduf-2.2 let-721 let-721 CBG19435 CBG19435 ucp-4 ucp-4 atp-4 atp-4 CBG18827 CBG18827 ucr-2.3 ucr-2.3 mpc-1 mpc-1 idhg-1 idhg-1 asb-1 asb-1 suca-1 suca-1 CBG17385 CBG17385 CBG17040 CBG17040 CBG16819 CBG16819 CBG16817 CBG16817 nuo-4 nuo-4 CBG16523 CBG16523 CBG16522 CBG16522 ucr-2.1 ucr-2.1 idhb-1 idhb-1 cox-5a cox-5a taco-1 taco-1 CBG15682 CBG15682 CBG15343 CBG15343 par-2 par-2 sucl-2 sucl-2 mdh-2 mdh-2 nnt-1 nnt-1 CBG14786 CBG14786 asb-2 asb-2 CBG14242 CBG14242 CBG13913 CBG13913 pdha-1 pdha-1 nuo-2 nuo-2 idha-1 idha-1 CBG12806 CBG12806 sdha-2 sdha-2 asg-1 asg-1 atp-3 atp-3 nduf-7 nduf-7 fahd-1 fahd-1 pdp-1.2 pdp-1.2 CBG11961 CBG11961 CBG11960 CBG11960 mpc-2 mpc-2 CBG11706 CBG11706 CBG11518 CBG11518 asg-2 asg-2 nuo-6 nuo-6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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CBG09880Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (390 aa)
CBG09850NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (183 aa)
CBG09820Protein CBG09820. (139 aa)
cox-6bProtein CBG09819. (121 aa)
CBG09291Protein CBG09291. (1011 aa)
fum-1Protein CBR-FUM-1. (491 aa)
CBG09051Protein CBG09051. (139 aa)
CBG09080Protein CBG09080. (387 aa)
CBG09091Protein CBG09091. (348 aa)
atp-1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (579 aa)
CBG02478Protein CBG02478. (186 aa)
cyc-2.2Probable cytochrome c 2.2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (135 aa)
sco-1Protein CBR-SCO-1. (318 aa)
idhg-2Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
CBG03983Protein CBG03983. (255 aa)
nduf-5Protein CBR-NDUF-5. (121 aa)
cox-5bProtein CBR-CCO-1. (132 aa)
cox-7cProtein CBG03801. (84 aa)
dlat-1Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (507 aa)
CBG05318Protein CBG05318. (577 aa)
CBG06101Protein CBG06101. (210 aa)
CBG06063Protein CBG06063. (305 aa)
nuaf-3Protein CBR-NUAF-3. (208 aa)
CBG06643L-2-hydroxyglutarate dehydrogenase, mitochondrial. (434 aa)
nuo-5Protein CBR-NUO-5; Belongs to the complex I 75 kDa subunit family. (725 aa)
CBG06846Protein CBG06846. (190 aa)
pdhk-2Protein-serine/threonine kinase. (486 aa)
gas-1Protein CBR-GAS-1; Belongs to the complex I 49 kDa subunit family. (482 aa)
ucr-2.2Protein CBR-UCR-2.2. (483 aa)
sucl-1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (322 aa)
cyc-1Protein CBR-CYC-1. (285 aa)
cox-18Protein CBG08423. (311 aa)
atp6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (199 aa)
nd1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (291 aa)
cox-2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (231 aa)
ctb-1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa)
ogdh-12-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (1027 aa)
cts-1Probable citrate synthase, mitochondrial. (468 aa)
nuaf-1Probable complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Required for normal growth and reproduction (By similarity). Belongs to the CIA30 family. (340 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mediates resistance to enteropathogenic E.coli infection (By similarity); Belongs to the cytochrome b560 family. (184 aa)
CBG29118Protein CBG29118. (160 aa)
dlst-1Protein CBR-DLST-1. (474 aa)
CBG26557Protein CBG26557. (159 aa)
men-1Malic enzyme. (620 aa)
CBG27170Protein CBG27170. (200 aa)
CBG28046Protein CBG28046. (156 aa)
CBG26013Protein CBG26013. (430 aa)
CBG25625Protein CBG25625. (220 aa)
atp-5Protein CBR-ATP-5. (191 aa)
CBG23452Protein CBG23452. (107 aa)
aco-2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
cox-6aCytochrome c oxidase subunit 6A, mitochondrial. (129 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (645 aa)
CBG22500Protein CBG22500. (300 aa)
sft-1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (317 aa)
lin-66Protein CBR-LIN-66. (600 aa)
hpo-18Protein CBR-HPO-18. (54 aa)
dld-1Dihydrolipoyl dehydrogenase. (495 aa)
nuo-3Protein CBR-NUO-3. (131 aa)
coa-6Protein CBG21348. (555 aa)
CBG21200Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa)
atp-2ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (537 aa)
pdhb-1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (352 aa)
CBG21025Protein CBG21025. (259 aa)
CBG20910Protein CBG20910. (325 aa)
CBG20848Protein CBG20848. (354 aa)
CBG20773Protein CBG20773. (90 aa)
CBG20772Protein CBG20772. (164 aa)
CBG20679Protein CBG20679. (199 aa)
CBG02642Protein CBG02642. (102 aa)
CBG02643Protein CBG02643. (161 aa)
hphd-1Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG. Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily. (465 aa)
CBG02865Protein CBG02865. (486 aa)
CBG02872Protein CBG02872. (492 aa)
ooc-3Protein CBR-OOC-3. (412 aa)
nuo-1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa)
sdhd-1Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (145 aa)
ldh-1L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
CBG03221Protein CBG03221. (103 aa)
CBG02223Protein CBG02223. (260 aa)
CBG01548Protein CBG01548. (177 aa)
isp-1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa)
cyc-2.1Cytochrome c 2.1; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (112 aa)
CBG01746Protein CBG01746. (348 aa)
cox-11Protein CBG01804. (426 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (282 aa)
Cbr-sdhb-1Protein CBG00873. (442 aa)
CBG01005Protein CBG01005. (153 aa)
hsp-75Protein CBG00585. (672 aa)
sucg-1Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (415 aa)
CBG00422Protein CBG00422. (153 aa)
dlat-2Protein CBG00405. (338 aa)
CBG00301Protein CBG00301. (331 aa)
lsy-22Protein CBR-LSY-22. (306 aa)
gst-42Protein CBR-GST-42; Belongs to the GST superfamily. (215 aa)
CBG24506Protein CBG24506. (202 aa)
CBG24154Protein CBG24154. (212 aa)
pdp-1.1Protein CBG23932. (451 aa)
lpd-5Protein CBR-LPD-5. (176 aa)
CBG23568Protein CBG23568. (130 aa)
nduf-6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (140 aa)
CBG20309Protein CBG20309; Belongs to the GST superfamily. (223 aa)
nduf-9Protein CBG20301. (428 aa)
CBG20227Protein CBG20227. (240 aa)
CBG20020Protein CBG20020. (150 aa)
cox-4Protein CBG19770. (175 aa)
CBG19690Protein CBG19690; Belongs to the complex I LYR family. (163 aa)
nduf-2.2Protein CBR-NDUF-2.2; Belongs to the complex I 49 kDa subunit family. (474 aa)
let-721Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (597 aa)
CBG19435Protein CBG19435. (333 aa)
ucp-4Protein CBR-UCP-4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa)
atp-4Protein CBR-ATP-4. (129 aa)
CBG18827Protein CBG18827. (92 aa)
ucr-2.3Protein CBR-UCR-2.3. (433 aa)
mpc-1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (154 aa)
idhg-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
asb-1Protein CBR-ASB-1. (301 aa)
suca-1Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (435 aa)
CBG17385Protein CBG17385. (296 aa)
CBG17040Protein CBG17040. (663 aa)
CBG16819Protein CBG16819. (93 aa)
CBG16817Protein CBG16817. (266 aa)
nuo-4NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (436 aa)
CBG16523Protein CBG16523. (101 aa)
CBG16522Protein CBG16522. (138 aa)
ucr-2.1Protein CBR-UCR-2.1. (410 aa)
idhb-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
cox-5aProtein CBR-CCO-2. (174 aa)
taco-1Protein CBG15714. (280 aa)
CBG15682Protein CBG15682. (462 aa)
CBG15343Protein CBG15343. (298 aa)
par-2Protein CBR-PAR-2. (647 aa)
sucl-2Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (321 aa)
mdh-2Malate dehydrogenase. (341 aa)
nnt-1Protein CBR-NNT-1. (1089 aa)
CBG14786Protein CBG14786. (83 aa)
asb-2Protein CBR-ASB-2. (305 aa)
CBG14242Protein CBG14242. (298 aa)
CBG13913NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa)
pdha-1Protein CBR-PDHA-1. (300 aa)
nuo-2Protein CBR-NUO-2; Belongs to the complex I 30 kDa subunit family. (399 aa)
idha-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (360 aa)
CBG12806Protein CBG12806. (171 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
asg-1Protein CBR-ASG-1. (131 aa)
atp-3Protein CBR-ATP-3. (207 aa)
nduf-7Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa)
fahd-1Protein CBG12264. (216 aa)
pdp-1.2Protein CBG12191. (499 aa)
CBG11961Protein CBG11961. (498 aa)
CBG11960Protein CBG11960. (123 aa)
mpc-2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (132 aa)
CBG11706ATP synthase lipid-binding protein, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (116 aa)
CBG11518Protein CBG11518. (239 aa)
asg-2Protein CBR-ASG-2. (131 aa)
nuo-6Protein CBR-NUO-6. (172 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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