(21 nodes) Synthesis of bile acids and bile salts network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	obr-2	Oxysterol-binding protein; Belongs to the OSBP family. (430 aa)
	CBG00232	Protein CBG00232. (345 aa)
	CBG02443	Protein CBG02443. (310 aa)
	CBG02441	Protein CBG02441. (317 aa)
	CBG06958	Protein CBG06958. (430 aa)
	dhs-6	Protein CBR-DHS-6. (418 aa)
	CBG08033	Protein CBG08033. (293 aa)
	CBG08596	Protein CBG08596. (323 aa)
	CBG08841	Protein CBG08841. (353 aa)
	CBG10451	Protein CBG10451. (415 aa)
	CBG10452	Protein CBG10452. (428 aa)
	CBG10453	Protein CBG10453. (428 aa)
	CBG10454	Protein CBG10454. (432 aa)
	CBG10455	Protein CBG10455. (252 aa)
	dhs-28	Protein CBR-DHS-28; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (448 aa)
	maoc-1	Protein CBR-MAOC-1. (298 aa)
	obr-1	Oxysterol-binding protein; Belongs to the OSBP family. (762 aa)
	nlt-1	Protein CBR-NLT-1. (118 aa)
	daf-22	Protein CBG20965; Belongs to the thiolase-like superfamily. Thiolase family. (372 aa)
	CBG22797	Protein CBG22797. (293 aa)
	CBG08110	Protein CBG08110. (360 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00232	CBG06958	A8WMI4	A8X420	Protein CBG00232.	Protein CBG06958.	0.915
CBG00232	daf-22	A8WMI4	A8XZ23	Protein CBG00232.	Protein CBG20965; Belongs to the thiolase-like superfamily. Thiolase family.	0.454
CBG00232	dhs-28	A8WMI4	A8XC82	Protein CBG00232.	Protein CBR-DHS-28; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.616
CBG00232	dhs-6	A8WMI4	A8X421	Protein CBG00232.	Protein CBR-DHS-6.	0.915
CBG00232	maoc-1	A8WMI4	A8XH22	Protein CBG00232.	Protein CBR-MAOC-1.	0.612
CBG00232	nlt-1	A8WMI4	A8XHX6	Protein CBG00232.	Protein CBR-NLT-1.	0.575
CBG02441	maoc-1	A8WUB4	A8XH22	Protein CBG02441.	Protein CBR-MAOC-1.	0.416
CBG02443	maoc-1	A8WUB3	A8XH22	Protein CBG02443.	Protein CBR-MAOC-1.	0.416
CBG06958	CBG00232	A8X420	A8WMI4	Protein CBG06958.	Protein CBG00232.	0.915
CBG06958	daf-22	A8X420	A8XZ23	Protein CBG06958.	Protein CBG20965; Belongs to the thiolase-like superfamily. Thiolase family.	0.685
CBG06958	dhs-6	A8X420	A8X421	Protein CBG06958.	Protein CBR-DHS-6.	0.691
CBG06958	maoc-1	A8X420	A8XH22	Protein CBG06958.	Protein CBR-MAOC-1.	0.731
CBG08033	maoc-1	A8X5M3	A8XH22	Protein CBG08033.	Protein CBR-MAOC-1.	0.412
CBG08110	maoc-1	G2J670	A8XH22	Protein CBG08110.	Protein CBR-MAOC-1.	0.416
CBG08841	maoc-1	A8X7I4	A8XH22	Protein CBG08841.	Protein CBR-MAOC-1.	0.416
CBG10451	CBG10452	A8XB90	A8XB91	Protein CBG10451.	Protein CBG10452.	0.901
CBG10451	CBG10453	A8XB90	A8XB92	Protein CBG10451.	Protein CBG10453.	0.901
CBG10451	CBG10454	A8XB90	A8XB93	Protein CBG10451.	Protein CBG10454.	0.902
CBG10452	CBG10451	A8XB91	A8XB90	Protein CBG10452.	Protein CBG10451.	0.901
CBG10452	CBG10453	A8XB91	A8XB92	Protein CBG10452.	Protein CBG10453.	0.900