STRINGSTRING
rpn-2 rpn-2 lin-23 lin-23 mom-4 mom-4 CBG06585 CBG06585 tap-1 tap-1 pbs-2 pbs-2 ubq-1 ubq-1 pas-6 pas-6 malt-1 malt-1 rpn-8 rpn-8 CBG12102 CBG12102 pas-4 pas-4 rpt-5 rpt-5 ubq-2 ubq-2 zak-1 zak-1 CBG17796 CBG17796 kxd-1 kxd-1 pbs-5 pbs-5 ubl-1 ubl-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpn-226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa)
lin-23Protein CBR-LIN-23. (682 aa)
mom-4Mitogen-activated protein kinase kinase kinase mom-4; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Stimulates the wrm-1/lit-1-dependent phosphorylation of pop-1 and plays a role in the initial nuclear accumulation of wrm-1 (By similarity). (545 aa)
CBG06585Protein CBG06585. (534 aa)
tap-1Protein CBR-TAP-1. (389 aa)
pbs-2Proteasome subunit beta. (277 aa)
ubq-1Protein CBR-UBQ-1. (770 aa)
pas-6Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa)
malt-1Protein CBG11191. (638 aa)
rpn-8Protein CBR-RPN-8. (382 aa)
CBG12102Protein CBG12102. (186 aa)
pas-4Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa)
rpt-5Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa)
ubq-2Protein CBR-UBQ-2. (128 aa)
zak-1Protein CBR-ZAK-1. (769 aa)
CBG17796Protein CBG17796. (53 aa)
kxd-1Protein CBG19105. (130 aa)
pbs-5Protein CBR-PBS-5. (284 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the N-terminal section; belongs to the ubiquitin family. (163 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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