Your Input: | |
| | aap-1 | Protein CBR-AAP-1. (522 aa) |
| | plx-2 | Plexin-2; Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis. (1773 aa) |
| | efn-4 | Ephrin-4; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, involved in ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays. Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis; Belongs to the ephrin family. (354 aa) |
| | dhp-2 | Dihydropyrimidinase 2; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (518 aa) |
| | arx-1 | Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (426 aa) |
| | daf-21 | Heat shock protein 90; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...] (706 aa) |
| | arx-2 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (393 aa) |
| | dhp-1 | Dihydropyrimidinase 1. (489 aa) |
| | mab-20 | Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (656 aa) |
| | age-1 | Phosphatidylinositol 3-kinase age-1; Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the [...] (1159 aa) |
| | Cbr-sax-7 | Protein CBR-SAX-7. (1402 aa) |
| | spe-4 | Protein CBR-SPE-4. (483 aa) |
| | CBG16668 | Protein CBG16668. (2334 aa) |
| | CBG25184 | Protein CBG25184. (1573 aa) |
| | CBG25355 | Protein CBG25355. (201 aa) |
| | CBG25604 | Protein CBG25604. (262 aa) |
| | CBG21718 | Protein CBG21718. (1544 aa) |
| | aph-1 | Protein CBR-APH-1. (330 aa) |
| | sma-1 | Protein CBR-SMA-1. (4156 aa) |
| | CBG23363 | Protein CBG23363. (206 aa) |
| | tln-1 | Protein CBG22153. (1036 aa) |
| | drag-1 | Protein CBR-DRAG-1. (414 aa) |
| | spe-48 | Protein CBG22135. (329 aa) |
| | gap-3 | Protein CBG22075. (960 aa) |
| | aph-2 | Protein CBR-APH-2. (721 aa) |
| | cdk-5 | Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa) |
| | mpk-1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa) |
| | mapk-15 | Mitogen-activated protein kinase. (458 aa) |
| | clic-1 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (217 aa) |
| | unc-5 | Protein CBR-UNC-5. (922 aa) |
| | smp-1 | Protein CBR-SMP-1; Belongs to the semaphorin family. (714 aa) |
| | CBG19473 | Protein CBG19473. (96 aa) |
| | unc-70 | Spectrin beta chain; Belongs to the spectrin family. (2370 aa) |
| | arx-3 | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (382 aa) |
| | cdka-1 | Cyclin-dependent kinase 5 activator. (366 aa) |
| | arx-6 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa) |
| | cnt-2 | Protein CBR-CNT-2. (1161 aa) |
| | zig-5 | Protein CBR-ZIG-5. (255 aa) |
| | dgn-1 | Protein CBR-DGN-1. (594 aa) |
| | CBG17392 | Protein CBG17392. (1745 aa) |
| | sem-5 | Protein CBR-SEM-5. (229 aa) |
| | zig-3 | Protein CBR-ZIG-3. (244 aa) |
| | zig-4 | Protein CBR-ZIG-4. (250 aa) |
| | viro-2 | Protein CBG16600. (552 aa) |
| | apa-2 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (925 aa) |
| | dgn-2 | Protein CBR-DGN-2. (395 aa) |
| | CBG16014 | Protein CBG16014. (2753 aa) |
| | him-4 | Protein CBR-HIM-4. (2899 aa) |
| | arx-5 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa) |
| | ral-1 | Protein CBR-RAL-1. (213 aa) |
| | CBG15514 | Protein CBG15514. (232 aa) |
| | unc-33 | Protein CBR-UNC-33. (862 aa) |
| | cdap-2 | Protein CBG14969. (544 aa) |
| | unc-40 | Protein CBR-UNC-40. (1407 aa) |
| | CBG14863 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa) |
| | pak-1 | Non-specific serine/threonine protein kinase. (626 aa) |
| | aps-2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa) |
| | dpy-23 | Protein CBR-DPY-23; Belongs to the adaptor complexes medium subunit family. (435 aa) |
| | nck-1 | Protein CBR-NCK-1. (393 aa) |
| | sax-3 | Protein CBR-SAX-3. (1295 aa) |
| | spc-1 | Protein CBR-SPC-1. (2467 aa) |
| | CBG13916 | Protein CBG13916. (1173 aa) |
| | plx-1 | Protein CBR-PLX-1. (1959 aa) |
| | CBG13699 | Protein CBG13699. (277 aa) |
| | rho-1 | Protein CBR-RHO-1. (192 aa) |
| | vab-1 | Protein CBR-VAB-1. (1118 aa) |
| | pen-2 | Protein CBR-PEN-2. (101 aa) |
| | CBG12765 | Protein CBG12765. (713 aa) |
| | CBG12470 | Protein CBG12470. (171 aa) |
| | hop-1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa) |
| | CBG12078 | Protein CBG12078. (812 aa) |
| | unc-73 | Protein CBR-UNC-73. (1618 aa) |
| | smp-2 | Protein CBR-SMP-2; Belongs to the semaphorin family. (689 aa) |
| | CBG10797 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (215 aa) |
| | vab-2 | Protein CBR-VAB-2; Belongs to the ephrin family. (242 aa) |
| | chc-1 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1660 aa) |
| | unc-44.1 | Protein CBG09456. (1857 aa) |
| | unc-44.2 | Protein CBG09473. (5237 aa) |
| | ubq-1 | Protein CBR-UBQ-1. (770 aa) |
| | mig-21 | Protein CBR-MIG-21. (297 aa) |
| | soc-1 | Protein CBR-SOC-1. (510 aa) |
| | rskn-2 | Ribosomal protein S6 kinase. (772 aa) |
| | CBG08105 | Protein CBG08105. (210 aa) |
| | sel-12 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa) |
| | gsk-3 | Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa) |
| | CBG07284 | Protein CBG07284. (251 aa) |
| | efn-3 | Protein CBR-EFN-3; Belongs to the ephrin family. (200 aa) |
| | CBG07560 | Protein CBG07560; Belongs to the protein kinase superfamily. (367 aa) |
| | slt-1 | Protein CBR-SLT-1. (1376 aa) |
| | unc-60 | Protein CBR-UNC-60; Belongs to the actin-binding proteins ADF family. (293 aa) |
| | let-60 | Protein CBR-LET-60. (184 aa) |
| | shc-1 | Protein CBR-SHC-1. (317 aa) |
| | sdn-1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (298 aa) |
| | efn-2 | Protein CBR-EFN-2; Belongs to the ephrin family. (219 aa) |
| | ebax-1 | Protein CBR-PQN-55. (1703 aa) |
| | zig-1 | Protein CBR-ZIG-1. (265 aa) |
| | arx-7 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (152 aa) |
| | mek-2 | Protein CBR-MEK-2; Belongs to the protein kinase superfamily. (387 aa) |
| | lim-7 | Protein CBR-LIM-7. (458 aa) |
| | CBG03641 | Protein CBG03641. (153 aa) |
| | lad-2 | Protein CBR-LAD-2. (1216 aa) |
| | mpk-2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (573 aa) |
| | CBG02328 | Protein CBG02328. (438 aa) |
| | nmr-1 | Protein CBR-NMR-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1064 aa) |
| | zig-10 | Protein CBG02647. (320 aa) |
| | max-2 | Protein CBG02801. (317 aa) |
| | Cbr-max-2 | Protein CBR-MAX-2; Belongs to the protein kinase superfamily. (422 aa) |
| | pmk-3 | Mitogen-activated protein kinase. (466 aa) |
| | pmk-2 | Mitogen-activated protein kinase. (392 aa) |
| | pmk-1 | Mitogen-activated protein kinase. (377 aa) |
| | wsp-1 | Protein CBR-WSP-1. (785 aa) |
| | CBG01565 | Protein CBG01565. (188 aa) |
| | CBG01035 | Protein CBG01035. (422 aa) |
| | itsn-1 | Protein CBR-ITSN-1. (1099 aa) |
| | ttx-3 | Protein CBR-TTX-3. (380 aa) |
| | alp-1 | Protein CBR-ALP-1. (2170 aa) |
| | arx-4 | Protein CBR-ARX-4. (539 aa) |
