(45 nodes) Metal ion SLC transporters network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	zipt-2.4	Protein CBG14913. (443 aa)
	cdf-2	Protein CBR-CDF-2. (360 aa)
	zipt-7.1	Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels (By similarity). Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (By similarity). Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (By similarity). The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable [...] (392 aa)
	zipt-17	Protein CBR-TAG-141. (347 aa)
	CBG00805	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (78 aa)
	CBG01808	Protein CBG01808. (463 aa)
	CBG01705	Protein CBG01705. (499 aa)
	CBG01586	Protein CBG01586. (505 aa)
	CBG01948	Protein CBG01948. (249 aa)
	ssr-2	Protein CBR-SSR-2. (323 aa)
	zipt-3	Protein CBG02486. (364 aa)
	cdf-1	Protein CBR-CDF-1. (545 aa)
	CBG06567	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (468 aa)
	fpn-1.2	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (500 aa)
	zipt-7.2	Zinc transporter zipt-7.2; Zinc transporter; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (476 aa)
	CBG08664	Protein CBG08664. (130 aa)
	CBG08742	Protein CBG08742. (746 aa)
	CBG09737	Protein CBG09737. (395 aa)
	CBG10409	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (408 aa)
	smf-2	Protein CBR-SMF-2. (545 aa)
	smf-1	Protein CBR-SMF-1. (577 aa)
	CBG11156	Protein CBG11156. (162 aa)
	CBG12308	Protein CBG12308. (257 aa)
	zipt-15	Protein CBG13990. (421 aa)
	smf-3	Protein CBR-SMF-3. (560 aa)
	CBG15477	Protein CBG15477. (297 aa)
	rig-1	Protein CBR-RIG-1. (1170 aa)
	ttm-1	Protein CBR-TTM-1. (388 aa)
	CBG16370	Protein CBG16370. (284 aa)
	zipt-2.1	Protein CBG17638. (346 aa)
	zipt-1	Protein CBG19738. (323 aa)
	CBG20077	Protein CBG20077. (165 aa)
	CBG20078	Protein CBG20078. (137 aa)
	CBG20079	Protein CBG20079. (361 aa)
	CBG20346	Protein CBG20346. (533 aa)
	zipt-2.3	Protein CBG20732. (319 aa)
	CBG20975	Protein CBG20975. (270 aa)
	toc-1	Protein CBR-TOC-1. (413 aa)
	fpn-1.1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (499 aa)
	CBG22300	Protein CBG22300. (289 aa)
	zipt-16	Protein CBR-TAG-140. (511 aa)
	CBG23207	Protein CBG23207. (419 aa)
	CBG25193	Protein CBG25193. (141 aa)
	zipt-2.2	Protein CBG21041. (234 aa)
	CBG24005	Protein CBG24005. (193 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00805	smf-3	A8WNV7	A8XJ43	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Protein CBR-SMF-3.	0.593
CBG06567	smf-1	A8X2J8	A8XC68	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Protein CBR-SMF-1.	0.645
CBG06567	smf-2	A8X2J8	A8XC67	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Protein CBR-SMF-2.	0.646
CBG06567	smf-3	A8X2J8	A8XJ43	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Protein CBR-SMF-3.	0.666
CBG08742	cdf-1	A8X7A2	A8WZ45	Protein CBG08742.	Protein CBR-CDF-1.	0.475
CBG08742	zipt-1	A8X7A2	A8XWF6	Protein CBG08742.	Protein CBG19738.	0.785
CBG08742	zipt-2.3	A8X7A2	A8XYH1	Protein CBG08742.	Protein CBG20732.	0.749
CBG08742	zipt-7.1	A8X7A2	A8WMY3	Protein CBG08742.	Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels (By similarity). Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (By similarity). Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (By similarity). The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable [...]	0.711
CBG08742	zipt-7.2	A8X7A2	A8X482	Protein CBG08742.	Zinc transporter zipt-7.2; Zinc transporter; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.	0.506
CBG10409	smf-3	A8XB51	A8XJ43	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Protein CBR-SMF-3.	0.593
cdf-1	CBG08742	A8WZ45	A8X7A2	Protein CBR-CDF-1.	Protein CBG08742.	0.475
cdf-1	cdf-2	A8WZ45	A8WMB8	Protein CBR-CDF-1.	Protein CBR-CDF-2.	0.475
cdf-1	ttm-1	A8WZ45	A8XMR5	Protein CBR-CDF-1.	Protein CBR-TTM-1.	0.504
cdf-1	zipt-15	A8WZ45	A8XIW1	Protein CBR-CDF-1.	Protein CBG13990.	0.688
cdf-1	zipt-17	A8WZ45	A8WN00	Protein CBR-CDF-1.	Protein CBR-TAG-141.	0.412
cdf-1	zipt-2.3	A8WZ45	A8XYH1	Protein CBR-CDF-1.	Protein CBG20732.	0.654
cdf-1	zipt-7.1	A8WZ45	A8WMY3	Protein CBR-CDF-1.	Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels (By similarity). Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (By similarity). Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (By similarity). The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable [...]	0.498
cdf-1	zipt-7.2	A8WZ45	A8X482	Protein CBR-CDF-1.	Zinc transporter zipt-7.2; Zinc transporter; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.	0.530
cdf-2	cdf-1	A8WMB8	A8WZ45	Protein CBR-CDF-2.	Protein CBR-CDF-1.	0.475
cdf-2	toc-1	A8WMB8	A8XZN0	Protein CBR-CDF-2.	Protein CBR-TOC-1.	0.516