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cox-2 cox-2 nd1 nd1 lpd-5 lpd-5 CBG24154 CBG24154 lsy-22 lsy-22 CBG00301 CBG00301 CBG00422 CBG00422 hsp-75 hsp-75 cox-11 cox-11 CBG01746 CBG01746 cyc-2.1 cyc-2.1 isp-1 isp-1 CBG01548 CBG01548 CBG02223 CBG02223 cox-7c cox-7c cox-5b cox-5b nduf-5 nduf-5 CBG03983 CBG03983 sco-1 sco-1 CBG02478 CBG02478 CBG02872 CBG02872 CBG23568 CBG23568 ooc-3 ooc-3 nuo-1 nuo-1 CBG03221 CBG03221 CBG06063 CBG06063 CBG06101 CBG06101 CBG05318 CBG05318 nuaf-3 nuaf-3 nuo-5 nuo-5 CBG06846 CBG06846 gas-1 gas-1 ucr-2.2 ucr-2.2 cyc-1 cyc-1 cox-18 cox-18 cyc-2.2 cyc-2.2 CBG09291 CBG09291 cox-6b cox-6b CBG09820 CBG09820 CBG09850 CBG09850 CBG09880 CBG09880 nuo-6 nuo-6 CBG11518 CBG11518 CBG11960 CBG11960 CBG11961 CBG11961 nduf-7 nduf-7 CBG12806 CBG12806 nuo-2 nuo-2 CBG13913 CBG13913 CBG14242 CBG14242 CBG14786 CBG14786 taco-1 taco-1 cox-5a cox-5a ucr-2.1 ucr-2.1 CBG16522 CBG16522 CBG16523 CBG16523 nuo-4 nuo-4 CBG16817 CBG16817 CBG16819 CBG16819 CBG17040 CBG17040 ucr-2.3 ucr-2.3 CBG18827 CBG18827 CBG19435 CBG19435 let-721 let-721 nduf-2.2 nduf-2.2 CBG19690 CBG19690 cox-4 cox-4 CBG20020 CBG20020 CBG20227 CBG20227 nduf-9 nduf-9 nduf-6 nduf-6 CBG20679 CBG20679 CBG20772 CBG20772 CBG20773 CBG20773 CBG20848 CBG20848 CBG21200 CBG21200 coa-6 coa-6 nuo-3 nuo-3 lin-66 lin-66 sft-1 sft-1 cox-6a cox-6a CBG26013 CBG26013 CBG28046 CBG28046 CBG26557 CBG26557 CBG29118 CBG29118 nuaf-1 nuaf-1 ctb-1 ctb-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cox-2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (231 aa)
nd1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (291 aa)
lpd-5Protein CBR-LPD-5. (176 aa)
CBG24154Protein CBG24154. (212 aa)
lsy-22Protein CBR-LSY-22. (306 aa)
CBG00301Protein CBG00301. (331 aa)
CBG00422Protein CBG00422. (153 aa)
hsp-75Protein CBG00585. (672 aa)
cox-11Protein CBG01804. (426 aa)
CBG01746Protein CBG01746. (348 aa)
cyc-2.1Cytochrome c 2.1; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (112 aa)
isp-1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa)
CBG01548Protein CBG01548. (177 aa)
CBG02223Protein CBG02223. (260 aa)
cox-7cProtein CBG03801. (84 aa)
cox-5bProtein CBR-CCO-1. (132 aa)
nduf-5Protein CBR-NDUF-5. (121 aa)
CBG03983Protein CBG03983. (255 aa)
sco-1Protein CBR-SCO-1. (318 aa)
CBG02478Protein CBG02478. (186 aa)
CBG02872Protein CBG02872. (492 aa)
CBG23568Protein CBG23568. (130 aa)
ooc-3Protein CBR-OOC-3. (412 aa)
nuo-1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa)
CBG03221Protein CBG03221. (103 aa)
CBG06063Protein CBG06063. (305 aa)
CBG06101Protein CBG06101. (210 aa)
CBG05318Protein CBG05318. (577 aa)
nuaf-3Protein CBR-NUAF-3. (208 aa)
nuo-5Protein CBR-NUO-5; Belongs to the complex I 75 kDa subunit family. (725 aa)
CBG06846Protein CBG06846. (190 aa)
gas-1Protein CBR-GAS-1; Belongs to the complex I 49 kDa subunit family. (482 aa)
ucr-2.2Protein CBR-UCR-2.2. (483 aa)
cyc-1Protein CBR-CYC-1. (285 aa)
cox-18Protein CBG08423. (311 aa)
cyc-2.2Probable cytochrome c 2.2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (135 aa)
CBG09291Protein CBG09291. (1011 aa)
cox-6bProtein CBG09819. (121 aa)
CBG09820Protein CBG09820. (139 aa)
CBG09850NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (183 aa)
CBG09880Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (390 aa)
nuo-6Protein CBR-NUO-6. (172 aa)
CBG11518Protein CBG11518. (239 aa)
CBG11960Protein CBG11960. (123 aa)
CBG11961Protein CBG11961. (498 aa)
nduf-7Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa)
CBG12806Protein CBG12806. (171 aa)
nuo-2Protein CBR-NUO-2; Belongs to the complex I 30 kDa subunit family. (399 aa)
CBG13913NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa)
CBG14242Protein CBG14242. (298 aa)
CBG14786Protein CBG14786. (83 aa)
taco-1Protein CBG15714. (280 aa)
cox-5aProtein CBR-CCO-2. (174 aa)
ucr-2.1Protein CBR-UCR-2.1. (410 aa)
CBG16522Protein CBG16522. (138 aa)
CBG16523Protein CBG16523. (101 aa)
nuo-4NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (436 aa)
CBG16817Protein CBG16817. (266 aa)
CBG16819Protein CBG16819. (93 aa)
CBG17040Protein CBG17040. (663 aa)
ucr-2.3Protein CBR-UCR-2.3. (433 aa)
CBG18827Protein CBG18827. (92 aa)
CBG19435Protein CBG19435. (333 aa)
let-721Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (597 aa)
nduf-2.2Protein CBR-NDUF-2.2; Belongs to the complex I 49 kDa subunit family. (474 aa)
CBG19690Protein CBG19690; Belongs to the complex I LYR family. (163 aa)
cox-4Protein CBG19770. (175 aa)
CBG20020Protein CBG20020. (150 aa)
CBG20227Protein CBG20227. (240 aa)
nduf-9Protein CBG20301. (428 aa)
nduf-6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (140 aa)
CBG20679Protein CBG20679. (199 aa)
CBG20772Protein CBG20772. (164 aa)
CBG20773Protein CBG20773. (90 aa)
CBG20848Protein CBG20848. (354 aa)
CBG21200Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa)
coa-6Protein CBG21348. (555 aa)
nuo-3Protein CBR-NUO-3. (131 aa)
lin-66Protein CBR-LIN-66. (600 aa)
sft-1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (317 aa)
cox-6aCytochrome c oxidase subunit 6A, mitochondrial. (129 aa)
CBG26013Protein CBG26013. (430 aa)
CBG28046Protein CBG28046. (156 aa)
CBG26557Protein CBG26557. (159 aa)
CBG29118Protein CBG29118. (160 aa)
nuaf-1Probable complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Required for normal growth and reproduction (By similarity). Belongs to the CIA30 family. (340 aa)
ctb-1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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