Your Input: | |||||
CBG23584 | Protein CBG23584. (252 aa) | ||||
nud-2 | Protein CBR-NUD-2. (281 aa) | ||||
npp-6 | Protein CBR-NPP-6. (1549 aa) | ||||
CBG23770 | Protein CBG23770. (299 aa) | ||||
CBG23920 | Protein CBG23920; Belongs to the AAA ATPase family. (268 aa) | ||||
rpn-11 | Protein CBR-RPN-11. (312 aa) | ||||
rpn-2 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa) | ||||
nud-1 | Protein CBR-NUD-1. (311 aa) | ||||
CBG24546 | Protein CBG24546. (299 aa) | ||||
rfc-4 | Protein CBR-RFC-4.2. (335 aa) | ||||
CBG00041 | Protein CBG00041; Belongs to the protein kinase superfamily. (296 aa) | ||||
emb-27 | Protein CBR-EMB-27. (669 aa) | ||||
zyg-9 | Protein CBR-ZYG-9. (1427 aa) | ||||
CBG00525 | Protein CBG00525; Belongs to the protein kinase superfamily. (296 aa) | ||||
CBG01828 | Protein CBG01828. (433 aa) | ||||
rfc-3 | Protein CBR-RFC-3. (354 aa) | ||||
dli-1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (441 aa) | ||||
pas-5 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (258 aa) | ||||
rmh-1 | Protein CBG02237. (944 aa) | ||||
CBG02222 | Protein CBG02222. (436 aa) | ||||
mus-101 | Protein CBR-MUS-101. (1175 aa) | ||||
ska-1 | Spindle and kinetochore-associated protein 1 homolog; Component of the ska-1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The ska-1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtu [...] (239 aa) | ||||
dna-2 | Protein CBR-DNA-2. (1123 aa) | ||||
ebp-2 | Protein CBR-EBP-2. (306 aa) | ||||
orc-2 | Protein CBR-ORC-2. (544 aa) | ||||
mat-2 | Protein CBR-MAT-2. (1853 aa) | ||||
rpn-9 | Protein CBR-RPN-9. (382 aa) | ||||
rpn-12 | Protein CBR-RPN-12. (250 aa) | ||||
hpr-17 | Protein CBR-HPR-17. (497 aa) | ||||
wrn-1 | Protein CBR-WRN-1. (1061 aa) | ||||
pbs-3 | Proteasome subunit beta. (204 aa) | ||||
CBG03383 | Protein CBG03383. (567 aa) | ||||
npp-18 | Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus; Belongs to the WD repeat SEC13 family. (366 aa) | ||||
brc-1 | Protein CBR-BRC-1. (498 aa) | ||||
mcm-4 | DNA helicase; Belongs to the MCM family. (830 aa) | ||||
CBG03913 | Protein CBG03913. (215 aa) | ||||
cdc-7 | Protein CBR-CDC-7; Belongs to the protein kinase superfamily. (409 aa) | ||||
npp-2 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (614 aa) | ||||
hsr-9 | Protein CBR-HSR-9. (1165 aa) | ||||
CBG03866 | Protein CBG03866. (1794 aa) | ||||
icp-1 | Protein CBR-ICP-1. (516 aa) | ||||
rpn-5 | Protein CBR-RPN-5. (491 aa) | ||||
pas-1 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa) | ||||
CBG04772 | Protein CBG04772; Belongs to the AAA ATPase family. (426 aa) | ||||
paa-1 | Protein CBR-PAA-1. (606 aa) | ||||
dyci-1 | Protein CBR-DYCI-1. (663 aa) | ||||
dlc-5 | Protein CBR-DLC-5. (186 aa) | ||||
cyb-3 | Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa) | ||||
ebp-1 | Protein CBR-EBP-1. (303 aa) | ||||
let-92 | Serine/threonine-protein phosphatase. (318 aa) | ||||
par-5 | Protein CBR-PAR-5; Belongs to the 14-3-3 family. (248 aa) | ||||
rpn-1 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (992 aa) | ||||
rpn-6.2 | Probable 26S proteasome regulatory subunit rpn-6.2; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family. (411 aa) | ||||
CBG06911 | Protein CBG06911. (254 aa) | ||||
cya-1 | Protein CBG06936; Belongs to the cyclin family. (467 aa) | ||||
CBG07148 | Protein CBG07148. (700 aa) | ||||
CBG07147 | Protein CBG07147. (318 aa) | ||||
CBG07138 | Protein CBG07138. (178 aa) | ||||
rpt-4 | Protein CBR-RPT-4; Belongs to the AAA ATPase family. (398 aa) | ||||
gfi-3 | Protein CBR-GFI-3. (794 aa) | ||||
pbs-2 | Proteasome subunit beta. (277 aa) | ||||
CBG08524 | Protein CBG08524. (1917 aa) | ||||
CBG08884 | Protein CBG08884. (289 aa) | ||||
CBG08885 | Protein CBG08885. (257 aa) | ||||
rpt-3 | Protein CBR-RPT-3; Belongs to the AAA ATPase family. (417 aa) | ||||
him-10 | Protein CBR-HIM-10. (637 aa) | ||||
ubq-1 | Protein CBR-UBQ-1. (770 aa) | ||||
npp-10 | Protein CBR-NPP-10. (1684 aa) | ||||
evl-18 | Protein CBG09214. (997 aa) | ||||
pas-2 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (231 aa) | ||||
mre-11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (727 aa) | ||||
apc-10 | Protein CBR-APC-10. (144 aa) | ||||
pas-6 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa) | ||||
rpt-2 | Protein CBR-RPT-2; Belongs to the AAA ATPase family. (443 aa) | ||||
bub-1 | Protein CBR-BUB-1. (971 aa) | ||||
clip-1 | Protein CBG10142. (961 aa) | ||||
CBG10242 | Protein CBG10242. (358 aa) | ||||
CBG10241 | Protein CBG10241. (289 aa) | ||||
CBG10240 | Protein CBG10240; Belongs to the protein kinase superfamily. (295 aa) | ||||
CBG10664 | Protein CBG10664. (295 aa) | ||||
CBG10679 | Protein CBG10679. (409 aa) | ||||
pas-3 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa) | ||||
CBG10818 | Histone H2B; Belongs to the histone H2B family. (123 aa) | ||||
mat-1 | Protein CBR-MAT-1. (746 aa) | ||||
psmd-9 | Protein CBG11181. (196 aa) | ||||
bir-2 | Protein CBR-BIR-2. (306 aa) | ||||
mcm-3 | Protein CBR-MCM-3; Belongs to the MCM family. (812 aa) | ||||
rpt-6 | Protein CBR-RPT-6; Belongs to the AAA ATPase family. (417 aa) | ||||
hus-1 | Checkpoint protein; Belongs to the HUS1 family. (207 aa) | ||||
pbs-4 | Proteasome subunit beta. (196 aa) | ||||
CBG12075 | Protein CBG12075. (611 aa) | ||||
rpn-8 | Protein CBR-RPN-8. (382 aa) | ||||
CBG12102 | Protein CBG12102. (186 aa) | ||||
cdc-6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (531 aa) | ||||
ran-2 | Protein CBR-RAN-2. (975 aa) | ||||
npp-15 | Protein CBR-NPP-15. (1146 aa) | ||||
mcm-5 | DNA helicase; Belongs to the MCM family. (771 aa) | ||||
CBG12411 | Protein CBG12411. (518 aa) | ||||
pbs-7 | Proteasome subunit beta; Belongs to the peptidase T1B family. (251 aa) | ||||
pas-4 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa) | ||||
rpn-10 | Protein CBR-RPN-10. (347 aa) | ||||
rpt-5 | Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa) | ||||
mat-3 | Protein CBR-MAT-3. (667 aa) | ||||
san-1 | Protein CBR-SAN-1. (390 aa) | ||||
cki-1 | Protein CBR-CKI-1. (187 aa) | ||||
mcm-10 | Protein CBG13203. (659 aa) | ||||
mrt-2 | Protein CBR-MRT-2. (267 aa) | ||||
CBG13260 | Protein CBG13260. (251 aa) | ||||
such-1 | Protein CBR-SUCH-1. (769 aa) | ||||
top-3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (774 aa) | ||||
pas-7 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa) | ||||
CBG13581 | Protein CBG13581. (651 aa) | ||||
pbs-1 | Proteasome subunit beta. (239 aa) | ||||
dlc-3 | Dynein light chain. (136 aa) | ||||
npp-20 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat; Belongs to the WD repeat SEC13 family. (306 aa) | ||||
mdf-2 | Protein CBR-MDF-2. (203 aa) | ||||
mltn-13 | Protein CBR-MLTN-13. (752 aa) | ||||
klp-13 | Protein CBR-KLP-13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (602 aa) | ||||
CBG14893 | Protein CBG14893. (521 aa) | ||||
npp-7 | Protein CBR-NPP-7. (1226 aa) | ||||
CBG15275 | Protein CBG15275. (342 aa) | ||||
CBG15203 | Protein CBG15203. (648 aa) | ||||
ubq-2 | Protein CBR-UBQ-2. (128 aa) | ||||
CBG15809 | Protein CBG15809. (626 aa) | ||||
CBG16303 | Protein CBG16303. (552 aa) | ||||
rpn-6.1 | Protein CBR-RPN-6.1. (404 aa) | ||||
Cbr-rfc-4.1 | Protein CBR-RFC-4.1. (340 aa) | ||||
rod-1 | Protein CBR-ROD-1. (2213 aa) | ||||
mksr-2 | Protein CBR-MKSR-2. (175 aa) | ||||
clsp-1 | Protein CBG16944. (676 aa) | ||||
CBG17207 | Protein CBG17207. (455 aa) | ||||
ftt-2 | Protein CBR-FTT-2; Belongs to the 14-3-3 family. (248 aa) | ||||
czw-1 | Protein CBR-CZW-1. (778 aa) | ||||
cyb-1 | Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa) | ||||
orc-5 | Protein CBR-ORC-5. (398 aa) | ||||
CBG17796 | Protein CBG17796. (53 aa) | ||||
CBG17880 | Protein CBG17880. (678 aa) | ||||
com-1 | Protein CBR-COM-1. (641 aa) | ||||
klp-7 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (743 aa) | ||||
CBG18333 | Protein CBG18333. (497 aa) | ||||
orc-1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (651 aa) | ||||
orc-4 | Protein CBR-ORC-4. (384 aa) | ||||
hpr-9 | Protein CBR-HPR-9. (513 aa) | ||||
mel-28 | Protein CBR-MEL-28. (1559 aa) | ||||
apc-11 | Protein CBR-APC-11. (134 aa) | ||||
CBG18037 | Protein CBG18037. (490 aa) | ||||
rpn-3 | Protein CBR-RPN-3. (506 aa) | ||||
mcm-2 | DNA helicase; Belongs to the MCM family. (892 aa) | ||||
kxd-1 | Protein CBG19105. (130 aa) | ||||
glo-4 | Protein CBR-GLO-4. (1392 aa) | ||||
mdf-1 | Protein CBR-MDF-1. (681 aa) | ||||
CBG19304 | Histone H2B; Belongs to the histone H2B family. (122 aa) | ||||
atl-1 | Protein CBR-ATL-1; Belongs to the PI3/PI4-kinase family. (2556 aa) | ||||
CBG19367 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (239 aa) | ||||
rmh-2 | Protein CBG19410. (602 aa) | ||||
dlc-1 | Dynein light chain. (89 aa) | ||||
npp-4 | Protein CBR-NPP-4. (515 aa) | ||||
pbs-5 | Protein CBR-PBS-5. (284 aa) | ||||
chk-2 | Protein CBR-CHK-2. (289 aa) | ||||
xpo-1 | Protein CBR-XPO-1. (1075 aa) | ||||
bub-3 | Protein CBR-BUB-3. (342 aa) | ||||
CBG20697 | Protein CBG20697. (173 aa) | ||||
lis-1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (390 aa) | ||||
exo-1 | Protein CBR-EXO-1. (647 aa) | ||||
CBG21459 | Protein CBG21459. (655 aa) | ||||
rpn-7 | Protein CBR-RPN-7. (409 aa) | ||||
CBG21690 | Protein CBG21690. (1974 aa) | ||||
pezo-1 | Protein CBG21689. (862 aa) | ||||
him-6 | Protein CBR-HIM-6. (1005 aa) | ||||
CBG21674 | Protein CBG21674. (171 aa) | ||||
mcm-7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (729 aa) | ||||
CBG21913 | Protein CBG21913. (618 aa) | ||||
wee-1.1 | Protein CBG21908; Belongs to the protein kinase superfamily. (419 aa) | ||||
CBG21906 | Protein CBG21906. (185 aa) | ||||
CBG22011 | Protein CBG22011. (228 aa) | ||||
CBG22013 | Protein CBG22013. (1122 aa) | ||||
atm-1 | Protein CBR-ATM-1; Belongs to the PI3/PI4-kinase family. (639 aa) | ||||
pptr-1 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (531 aa) | ||||
rfc-2 | Protein CBR-RFC-2. (329 aa) | ||||
apc-2 | Protein CBR-APC-2; Belongs to the cullin family. (700 aa) | ||||
CBG22959 | Serine/threonine-protein phosphatase. (551 aa) | ||||
mdt-30 | Protein CBR-MDT-30. (524 aa) | ||||
CBG23443 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa) | ||||
rad-50 | Protein CBR-RAD-50. (1354 aa) | ||||
CBG23414 | Protein CBG23414. (1631 aa) | ||||
rpt-1 | Protein CBR-RPT-1; Belongs to the AAA ATPase family. (435 aa) | ||||
bir-1 | Protein CBR-BIR-1. (158 aa) | ||||
ndc-80 | Protein CBR-NDC-80. (599 aa) | ||||
pptr-2 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (556 aa) | ||||
CBG26344 | Protein CBG26344. (129 aa) | ||||
CBG25885 | Protein CBG25885. (307 aa) | ||||
CBG25886 | Protein CBG25886. (111 aa) | ||||
CBG26841 | Protein CBG26841. (245 aa) | ||||
CBG22319 | Protein CBG22319. (306 aa) | ||||
his-64 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
CBG01507 | Histone H2B; Belongs to the histone H2B family. (122 aa) | ||||
cki-2 | Protein CBR-CKI-2.1. (256 aa) | ||||
CBG20339 | Protein CBG20339; Belongs to the AAA ATPase family. (415 aa) | ||||
CBG24469 | Protein CBG24469. (272 aa) | ||||
rpa-1 | Probable replication factor A 73 kDa subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (658 aa) | ||||
zwl-1 | Protein zwilch homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of [...] (639 aa) | ||||
ubl-1 | Ubiquitin-like protein 1-40S ribosomal protein S27a; In the N-terminal section; belongs to the ubiquitin family. (163 aa) | ||||
mcm-6 | DNA replication licensing factor mcm-6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentia [...] (810 aa) | ||||
cls-2 | Protein CLASP-2; Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming (By similarity). (791 aa) | ||||
CBG09173 | Protein CLASP-1; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules; Belongs to the CLASP family. (1333 aa) | ||||
cls-3 | Protein CLASP-3; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules; Belongs to the CLASP family. (970 aa) | ||||
chk-1 | Serine/threonine-protein kinase chk-1; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Required for checkpoint mediated cell cycle arrest in response to DNA damage in germline cells. Essential for embryogenesis (By similarity); Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily. (493 aa) | ||||
wee-1.3 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. (656 aa) | ||||
cye-1 | G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] (518 aa) |