(58 nodes) Formation of the ternary complex, and subsequently, the 43S complex network (Caenorhabditis briggsae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	rps-24	Protein CBR-RPS-24. (131 aa)
	eif-3.E	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (311 aa)
	rps-15	Protein CBR-RPS-15; Belongs to the universal ribosomal protein uS19 family. (151 aa)
	rps-22	Protein CBR-RPS-22; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	CBG23661	Protein CBG23661. (255 aa)
	CBG23663	Protein CBG23663. (127 aa)
	rps-3	Protein CBR-RPS-3; Belongs to the universal ribosomal protein uS3 family. (247 aa)
	eif-3.G.1	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (261 aa)
	egl-45	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1098 aa)
	CBG01389	Protein CBG01389. (192 aa)
	cif-1	COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulat [...] (390 aa)
	rps-9	Protein CBR-RPS-9; Belongs to the universal ribosomal protein uS4 family. (189 aa)
	rps-23	Protein CBR-RPS-23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	eif-3.I	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (327 aa)
	eif-3.H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (365 aa)
	rps-19	Protein CBR-RPS-19. (146 aa)
	eif-3.C	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (894 aa)
	eif-2gamma	Protein CBG03884. (469 aa)
	eif-3.B	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (716 aa)
	rps-11	Protein CBR-RPS-11; Belongs to the universal ribosomal protein uS17 family. (155 aa)
	rps-5	Protein CBR-RPS-5; Belongs to the universal ribosomal protein uS7 family. (210 aa)
	CBG05978	Protein CBG05978. (89 aa)
	rps-8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	rps-4	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (259 aa)
	rps-27	Protein CBR-RPS-27. (83 aa)
	eif-3.D	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (574 aa)
	CBG06962	Protein CBG06962. (559 aa)
	eif-3.L	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (537 aa)
	eif-3.j	Protein CBG08014. (60 aa)
	eif-2beta	Protein CBR-IFTB-1. (250 aa)
	rps-20	Protein CBR-RPS-20. (117 aa)
	rps-12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (153 aa)
	CBG09497	Protein CBG09497. (958 aa)
	inx-7	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (551 aa)
	rps-25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (117 aa)
	rps-16	Protein CBR-RPS-16; Belongs to the universal ribosomal protein uS9 family. (144 aa)
	eif-1.a	Protein CBG11654; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (215 aa)
	eif-3.K	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (240 aa)
	rps-21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (88 aa)
	CBG25345	Protein CBG25345. (135 aa)
	CBG26383	Protein CBG26383. (359 aa)
	pqn-42	Protein CBR-PQN-42. (546 aa)
	rps-10	Protein CBR-RPS-10. (149 aa)
	eif-2alpha	Protein CBG22041. (342 aa)
	CBG21521	Protein CBG21521. (151 aa)
	rps-18	Protein CBR-RPS-18; Belongs to the universal ribosomal protein uS13 family. (154 aa)
	rps-7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	eif-3.f	Protein CBR-EIF-3.F; Belongs to the eIF-3 subunit F family. (251 aa)
	rps-26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (117 aa)
	rps-13	Protein CBR-RPS-13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	rps-1	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (257 aa)
	rps-0	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (278 aa)
	rps-2	Protein CBR-RPS-2. (85 aa)
	rps-29	Protein CBR-RPS-29. (138 aa)
	CBG14760	Protein CBG14760. (343 aa)
	rps-6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (260 aa)
	rps-28	Protein CBR-RPS-28. (65 aa)
	rps-17	Protein CBR-RPS-17. (130 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG01389	CBG05978	A8WQA8	A8X170	Protein CBG01389.	Protein CBG05978.	0.882
CBG01389	CBG06962	A8WQA8	A8X416	Protein CBG01389.	Protein CBG06962.	0.761
CBG01389	CBG09497	A8WQA8	A8X8Z3	Protein CBG01389.	Protein CBG09497.	0.777
CBG01389	CBG14760	A8WQA8	A8XKL9	Protein CBG01389.	Protein CBG14760.	0.580
CBG01389	CBG21521	A8WQA8	A8Y0B0	Protein CBG01389.	Protein CBG21521.	0.889
CBG01389	CBG23661	A8WQA8	A8WJ15	Protein CBG01389.	Protein CBG23661.	0.718
CBG01389	CBG23663	A8WQA8	A8WJ17	Protein CBG01389.	Protein CBG23663.	0.718
CBG01389	CBG25345	A8WQA8	B6IIK9	Protein CBG01389.	Protein CBG25345.	0.757
CBG01389	CBG26383	A8WQA8	B6IFE2	Protein CBG01389.	Protein CBG26383.	0.953
CBG01389	cif-1	A8WQA8	A8WQY8	Protein CBG01389.	COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulat [...]	0.823
CBG01389	egl-45	A8WQA8	A8WM57	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.934
CBG01389	eif-2alpha	A8WQA8	A8Y1E3	Protein CBG01389.	Protein CBG22041.	0.981
CBG01389	eif-2beta	A8WQA8	A8X625	Protein CBG01389.	Protein CBR-IFTB-1.	0.980
CBG01389	eif-2gamma	A8WQA8	A8WX01	Protein CBG01389.	Protein CBG03884.	0.968
CBG01389	eif-3.B	A8WQA8	A8WX15	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.934
CBG01389	eif-3.C	A8WQA8	A8WWU0	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.930
CBG01389	eif-3.D	A8WQA8	A8X371	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.	0.925
CBG01389	eif-3.E	A8WQA8	A8XFH3	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.922
CBG01389	eif-3.G.1	A8WQA8	A8WLV5	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.930
CBG01389	eif-3.H	A8WQA8	A8WVY9	Protein CBG01389.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.796