(18 nodes) Glutamate and glutamine metabolism network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nkat-3	Protein CBR-NKAT-3. (441 aa)
	nkat-1	Protein CBG10259. (425 aa)
	CBG10206	Protein CBG10206. (425 aa)
	glna-2	Protein CBR-GLNA-2. (662 aa)
	gln-3	Glutamine synthetase. (385 aa)
	gln-1	Protein CBR-GLN-1; Belongs to the glutamine synthetase family. (385 aa)
	CBG16221	Protein CBG16221. (279 aa)
	Cbr-gln-5	Protein CBR-GLN-5; Belongs to the glutamine synthetase family. (383 aa)
	gln-2.1	Protein CBG20640; Belongs to the glutamine synthetase family. (367 aa)
	oatr-1	Protein CBG09115; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
	got-2.1	Aspartate aminotransferase. (419 aa)
	gln-2.2	Protein CBR-GLN-2; Belongs to the glutamine synthetase family. (367 aa)
	glna-3	Protein CBR-GLNA-3. (600 aa)
	alh-13	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa)
	glna-1	Protein CBR-GLNA-1. (825 aa)
	got-2.2	Aspartate aminotransferase. (414 aa)
	gdh-1	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (536 aa)
	CBG05881	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (298 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG05881	CBG16221	A8X1F4	A8XNV3	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	Protein CBG16221.	0.990
CBG05881	alh-13	A8X1F4	A8WM90	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.957
CBG05881	oatr-1	A8X1F4	E3CU08	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	Protein CBG09115; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.728
CBG10206	alh-13	A8XAV0	A8WM90	Protein CBG10206.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.732
CBG10206	gdh-1	A8XAV0	A8X0P1	Protein CBG10206.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.558
CBG10206	got-2.1	A8XAV0	A8Y1V2	Protein CBG10206.	Aspartate aminotransferase.	0.545
CBG10206	got-2.2	A8XAV0	A8WYZ3	Protein CBG10206.	Aspartate aminotransferase.	0.952
CBG10206	nkat-1	A8XAV0	A8XAR6	Protein CBG10206.	Protein CBG10259.	0.900
CBG10206	nkat-3	A8XAV0	A8X492	Protein CBG10206.	Protein CBR-NKAT-3.	0.901
CBG16221	CBG05881	A8XNV3	A8X1F4	Protein CBG16221.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.990
CBG16221	alh-13	A8XNV3	A8WM90	Protein CBG16221.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.916
CBG16221	oatr-1	A8XNV3	E3CU08	Protein CBG16221.	Protein CBG09115; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.748
Cbr-gln-5	alh-13	A8XWM9	A8WM90	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.930
Cbr-gln-5	gdh-1	A8XWM9	A8X0P1	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.971
Cbr-gln-5	gln-1	A8XWM9	A8XKR8	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Protein CBR-GLN-1; Belongs to the glutamine synthetase family.	0.913
Cbr-gln-5	gln-2.1	A8XWM9	A8XY98	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Protein CBG20640; Belongs to the glutamine synthetase family.	0.921
Cbr-gln-5	gln-2.2	A8XWM9	A8XYH6	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Protein CBR-GLN-2; Belongs to the glutamine synthetase family.	0.921
Cbr-gln-5	gln-3	A8XWM9	A8XIS2	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.913
Cbr-gln-5	glna-1	A8XWM9	A8WX31	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Protein CBR-GLNA-1.	0.947
Cbr-gln-5	glna-2	A8XWM9	A8XHY8	Protein CBR-GLN-5; Belongs to the glutamine synthetase family.	Protein CBR-GLNA-2.	0.947