STRINGSTRING
marc-3 marc-3 crt-1 crt-1 ubl-1 ubl-1 sta-2 sta-2 CBG23361 CBG23361 uggt-2 uggt-2 CBG22020 CBG22020 marc-4 marc-4 mans-4 mans-4 marc-5 marc-5 aagr-3 aagr-3 kxd-1 kxd-1 CBG17796 CBG17796 uggt-1 uggt-1 ubq-2 ubq-2 mans-3 mans-3 marc-6 marc-6 CBG12102 CBG12102 cnx-1 cnx-1 ubq-1 ubq-1 aagr-4 aagr-4 CBG03437 CBG03437 CBG01952 CBG01952
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
marc-3Protein CBG03739. (462 aa)
crt-1Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress- induced neurodegeneration (By similarity). (396 aa)
ubl-1Ubiquitin-like protein 1-40S ribosomal protein S27a; In the N-terminal section; belongs to the ubiquitin family. (163 aa)
sta-2Protein CBR-STA-2. (771 aa)
CBG23361alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (775 aa)
uggt-2Protein CBG22023. (1280 aa)
CBG22020Protein CBG22020. (79 aa)
marc-4Protein CBG22019. (255 aa)
mans-4alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (527 aa)
marc-5Protein CBG20937. (473 aa)
aagr-3Protein CBG19359; Belongs to the glycosyl hydrolase 31 family. (924 aa)
kxd-1Protein CBG19105. (130 aa)
CBG17796Protein CBG17796. (53 aa)
uggt-1Protein CBG16703. (1495 aa)
ubq-2Protein CBR-UBQ-2. (128 aa)
mans-3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (589 aa)
marc-6Protein CBR-MARC-6. (1097 aa)
CBG12102Protein CBG12102. (186 aa)
cnx-1Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death (By similarity). (623 aa)
ubq-1Protein CBR-UBQ-1. (770 aa)
aagr-4Protein CBG08162; Belongs to the glycosyl hydrolase 31 family. (920 aa)
CBG03437alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (568 aa)
CBG01952alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (954 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (28%) [HD]