STRINGSTRING
mec-10 mec-10 mec-4 mec-4 unc-119 unc-119 unc-54 unc-54 egl-46 egl-46 mec-2 mec-2 trp-4 trp-4 asic-1 asic-1 unc-8 unc-8 pab-1 pab-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mec-10Degenerin mec-10; Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (724 aa)
mec-4Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (768 aa)
unc-119Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system (By similarity). Belongs to the PDE6D/unc-119 family. (217 aa)
unc-54Protein CBR-UNC-54; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2004 aa)
egl-46Protein CBR-EGL-46. (283 aa)
mec-2Protein CBR-MEC-2. (317 aa)
trp-4Protein CBR-TRP-4; Belongs to the transient receptor (TC 1.A.4) family. (2002 aa)
asic-1Protein CBR-ASIC-1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (842 aa)
unc-8Protein CBR-UNC-8; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (834 aa)
pab-1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (666 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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