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gld-1 | Protein CBR-GLD-1. (467 aa) | ||||
trr-1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions. Required for spermatogenesis and embryonic development. Acts with tra-2 to promote expression of fog-3 and control male tail development. Involved in the negative regulation of vulval development (By similarity). (4115 aa) | ||||
lin-3 | Protein CBR-LIN-3. (450 aa) | ||||
nurf-1 | Protein CBR-NURF-1. (1674 aa) | ||||
she-1 | F-box protein she-1; Sex-determining factor which regulates hermaphrodite development. (830 aa) | ||||
nath-10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1077 aa) | ||||
dpy-18 | Protein CBR-DPY-18. (1008 aa) | ||||
tra-4 | Protein CBR-TRA-4. (529 aa) | ||||
isw-1 | Protein CBR-ISW-1. (1019 aa) | ||||
fem-1 | Protein CBR-FEM-1. (660 aa) | ||||
spe-4 | Protein CBR-SPE-4. (483 aa) | ||||
tra-2 | Sex-determining transformer protein 2; Plays a major role in controlling sexual cell fates. Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote female development (By similarity). In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1 (By similarity). Negatively regulates male development when bound to fem-3 and is required together with tra-1 for prom [...] (1489 aa) | ||||
tra-1 | Sex-determining transformer protein 1; Plays a major role in controlling sexual phenotype. Terminal global regulator in a well-characterized cascade of sex-determining genes (By similarity). Promotes female development (By similarity). Interacts with tra-2 to promote spermatogenesis. Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development. Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2 (By similarity). With trr-1, activates the fog-3 gene to determ [...] (1165 aa) | ||||
lin-53 | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. (416 aa) | ||||
fog-1 | Protein CBR-FOG-1. (647 aa) | ||||
fog-3 | Protein CBR-FOG-3. (261 aa) |