STRINGSTRING
CBG09063 CBG09063 CBG20786 CBG20786 hsp-70 hsp-70 hda-3 hda-3 CBG15416 CBG15416 hda-2 hda-2 top-3 top-3 hda-1 hda-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG09063Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
CBG20786DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (591 aa)
hsp-70Protein CBR-HSP-70; Belongs to the heat shock protein 70 family. (651 aa)
hda-3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (462 aa)
CBG15416Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (470 aa)
hda-2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (503 aa)
top-3DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (774 aa)
hda-1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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