STRINGSTRING
trr-1 trr-1 CBG03566 CBG03566 piki-1 piki-1 pifk-1 pifk-1 vps-34 vps-34 age-1 age-1 smg-1 smg-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
trr-1Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions. Required for spermatogenesis and embryonic development. Acts with tra-2 to promote expression of fog-3 and control male tail development. Involved in the negative regulation of vulval development (By similarity). (4115 aa)
CBG03566Protein CBG03566; Belongs to the PI3/PI4-kinase family. (2096 aa)
piki-1Protein CBR-PIKI-1; Belongs to the PI3/PI4-kinase family. (1680 aa)
pifk-1Protein CBG08090; Belongs to the PI3/PI4-kinase family. (682 aa)
vps-34Phosphatidylinositol 3-kinase catalytic subunit type 3. (895 aa)
age-1Phosphatidylinositol 3-kinase age-1; Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the [...] (1159 aa)
smg-1Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2 (By similarity); Belongs to the PI3/PI4-kinase family. (2313 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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