STRINGSTRING
CBG22562 CBG22562 hgrs-1 hgrs-1 stam-1 stam-1 piki-1 piki-1 epn-1 epn-1 rpn-10 rpn-10 CBG17467 CBG17467 atx-3 atx-3 CBG22703 CBG22703
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG22562Protein CBG22562. (355 aa)
hgrs-1Protein CBR-HGRS-1. (728 aa)
stam-1Protein CBR-STAM-1. (471 aa)
piki-1Protein CBR-PIKI-1; Belongs to the PI3/PI4-kinase family. (1680 aa)
epn-1Protein CBR-EPN-1. (456 aa)
rpn-10Protein CBR-RPN-10. (347 aa)
CBG17467Protein CBG17467. (594 aa)
atx-3Ataxin-3 homolog; Acts as chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway. Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan. Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci. Interacts with key regulators of transcription and represses transcription. Acts as a [...] (319 aa)
CBG22703Protein CBG22703. (914 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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